Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adrian M. Harris"'
Autor:
Quoc D. Mac, Anirudh Sivakumar, Hathaichanok Phuengkham, Congmin Xu, James R. Bowen, Fang-Yi Su, Samuel Z. Stentz, Hyoungjun Sim, Adrian M. Harris, Tonia T. Li, Peng Qiu, Gabriel A. Kwong
Publikováno v:
Nat Biomed Eng
Immune checkpoint blockade (ICB) therapy does not benefit the majority of treated patients, and those who respond to the therapy can become resistant to it. Here we report the design and performance of systemically administered protease activity sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1d27abf6230ff6f87aadaea1551a7b
https://europepmc.org/articles/PMC8957521/
https://europepmc.org/articles/PMC8957521/
Autor:
Lena Gamboa, Ali H. Zamat, Daryll Vanover, Chloé A. Thiveaud, Hannah E. Peck, Hathaichanok Phuengkham, Anirudh Sivakumar, Adrian M. Harris, Shreyas N. Dahotre, Fang-Yi Su, Philip J. Santangelo, Gabriel A. Kwong
CAR T cell immunotherapy relies on CAR targeting of tumor-associated antigens, yet heterogenous antigen expression, interpatient variation, and off-tumor expression by healthy cells remain barriers. Here, we develop synthetic antigens to sensitize so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dbbada2c580ebfbc394cd30ecd7998
https://doi.org/10.1101/2021.12.11.472238
https://doi.org/10.1101/2021.12.11.472238
Autor:
Anirudh Sivakumar, Gabriel A. Kwong, Quoc D. Mac, Fang-Yi Su, Hathaichanok Phuengkham, Samuel Z Stentz, Bowen, Peng Qiu, Adrian M Harris, Li Tt, Congmin Xu, Sim H
Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, yet most patients do not derive clinical benefit and responders can acquire resistance to therapy. Noninvasive biomarkers are needed to indicate early on-treatment response an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fdd4f523f40ad879519f12c30cf096a
https://doi.org/10.1101/2020.12.10.420265
https://doi.org/10.1101/2020.12.10.420265
Autor:
Adrian M Harris, Samuel Z Stentz, Gabriel A. Kwong, Anirudh Sivakumar, Quoc D. Mac, Hathaichanok Phuengkham, Tonia Li, Peng Qiu, James Bowen, Hyoung Sim, Fang-Yi Su, Congmin Xu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Despite the curative potential of immune checkpoint blockade (ICB) therapy, only small subsets of patients achieve tumor regression while many responders relapse and acquire resistance. Monitoring treatment response and detecting the onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112d0b5023b91280cd60085261e019b5
https://doaj.org/article/fe831172323f470499bff3d2f5063dea
https://doaj.org/article/fe831172323f470499bff3d2f5063dea
Autor:
Ian C. Miller, Saul J. Priceman, Gabriel A. Kwong, Hathaichanok Phuengkham, Jason Yang, Adrian M Harris, John P. Murad, Lee-Kai Sun, Ali Zamat, Lena Gamboa
Publikováno v:
Nat Biomed Eng
Treating solid malignancies with chimeric antigen receptor (CAR) T cells typically results in poor responses. Immunomodulatory biologics delivered systemically can augment the cells’ activity, but off-target toxicity narrows the therapeutic window.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c71a24664fbc2f8673572ecb2aeaa7
https://pubmed.ncbi.nlm.nih.gov/34385695
https://pubmed.ncbi.nlm.nih.gov/34385695
The limited ability to control anti-tumor activity within tumor sites contributes to poor CAR T cell responses against solid malignancies. Systemic delivery of biologic drugs such as cytokines can augment CAR T cell activity despite off-target toxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18204f8ed585268e8089c7bcd9d910
https://doi.org/10.1101/2020.04.26.062703
https://doi.org/10.1101/2020.04.26.062703
Publikováno v:
Injury. 35:1303-1305
Grease gun trauma often involves subcutaneous injection of the grease because of the high pressures required for its industrial application. The case is presented of a man who developed a pneumonitis shortly after sustaining a grease gun injury, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1241f84ff6361da8e3c71e41ec503fd
https://doi.org/10.1016/j.injury.2003.09.008
https://doi.org/10.1016/j.injury.2003.09.008
Publikováno v:
JSLS : Journal of the Society of Laparoendoscopic Surgeons
The management of common bile duct stones has traditionally required open laparotomy and bile duct exploration. With the advent of endoscopic and laparoscopic technology in the latter half of the last century, endoscopic retrograde cholangiopancreato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42003b7ff1a8d870bdd58d029a930482
https://pubmed.ncbi.nlm.nih.gov/17651582
https://pubmed.ncbi.nlm.nih.gov/17651582