Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adrian Leistner"'
Autor:
Ruben Pawellek, Jovana Krmar, Adrian Leistner, Nevena Djajić, Biljana Otašević, Ana Protić, Ulrike Holzgrabe
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors that generate a response independent of the analytes’ chemical structure. This study was aimed at accurately predicting the CAD response of homologo
Externí odkaz:
https://doaj.org/article/8a0cdc642f4543929945594110545d92
Autor:
Rasmus Walther, Jovana Krmar, Adrian Leistner, Bojana Svrkota, Biljana Otašević, Andjelija Malenović, Ulrike Holzgrabe, Ana Protić
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 478 (2023)
An alternative to the time-consuming and error-prone pharmacopoeial gas chromatography method for the analysis of fatty acids (FAs) is urgently needed. The objective was therefore to propose a robust liquid chromatography method with charged aerosol
Externí odkaz:
https://doaj.org/article/8ef32e416f0b4464afdde9d101cbad72
Alternative methods to assess the impurity profile of a monographed API using acarbose as an example
Autor:
Adrian Leistner, Ulrike Holzgrabe
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 221
Even though the impurity analysis of the Ph. Eur. is considered well-studied, its methodology should be reviewed periodically to ensure that it is working properly, and all impurities are captured by the section "Related substances" of the monograph.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8795c201fad1679c02206577793548bf
https://pubmed.ncbi.nlm.nih.gov/36150297
https://pubmed.ncbi.nlm.nih.gov/36150297
Autor:
Adrian Leistner, Ulrike Holzgrabe
The GABABreceptor agonist baclofen is a medication commonly used for the treatment of muscle spasticity. It is an amino acid and related to the neurotransmitter GABA. In this study, we developed a new, gradient high-performance liquid chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d093d2c5b6b394bc31adb9354d539d
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-268921
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-268921
Autor:
Adrian Leistner, Ulrike Holzgrabe
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 198
The quality control of active pharmaceutical ingredients (APIs) is a very important aspect for drug products entering the market. However, also for the well-established drugs, there ought to be a state-of-the-art impurity control. Some of the pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498ff91eb157a3db45ed4b75539e7134
https://pubmed.ncbi.nlm.nih.gov/33657522
https://pubmed.ncbi.nlm.nih.gov/33657522
Autor:
Ulrike Holzgrabe, Adrian Leistner, Joerg-Detlef Kreher, Ivonne Becker, Dirk Jung, Stephan Haerling
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 189
Recently, the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA) had reported on "unexpected" impurities in a couple of sartans, ranitidine, and metformin. These events led to a lot of discussion with regard to the risk a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9914b5aa556b9924bd13bd9abcc1b490
https://pubmed.ncbi.nlm.nih.gov/32599488
https://pubmed.ncbi.nlm.nih.gov/32599488