Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adrian López García de Lomana"'
Autor:
Serdar Turkarslan, Arjun V Raman, Anne W Thompson, Christina E Arens, Mark A Gillespie, Frederick vonNetzer, Kristina L Hillesland, Sergey Stolyar, Adrian López García de Lomana, David J Reiss, Drew Gorman‐Lewis, Grant M Zane, Jeffrey A Ranish, Judy D Wall, David A Stahl, Nitin S Baliga
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp n/a-n/a (2017)
Abstract Managing trade‐offs through gene regulation is believed to confer resilience to a microbial community in a fluctuating resource environment. To investigate this hypothesis, we imposed a fluctuating environment that required the sulfate‐r
Externí odkaz:
https://doaj.org/article/a655ac4e70d1467cac12e10d18846903
Autor:
Ulrike Kusebauch, Alan P. R. Lorenzetti, David S. Campbell, Min Pan, David Shteynberg, Charu Kapil, Mukul K. Midha, Adrián López García de Lomana, Nitin S. Baliga, Robert L. Moritz
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-14 (2023)
Abstract Data-Independent Acquisition (DIA) is a mass spectrometry-based method to reliably identify and reproducibly quantify large fractions of a target proteome. The peptide-centric data analysis strategy employed in DIA requires a priori generate
Externí odkaz:
https://doaj.org/article/43933e8e04844f75b041f4a5e2a61de9
Autor:
James H. Park, Abdullah H. Feroze, Samuel N. Emerson, Anca B. Mihalas, C. Dirk Keene, Patrick J. Cimino, Adrian Lopez Garcia de Lomana, Kavya Kannan, Wei-Ju Wu, Serdar Turkarslan, Nitin S. Baliga, Anoop P. Patel
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-13 (2022)
Abstract Glioblastoma (GBM) is a heterogeneous tumor made up of cell states that evolve over time. Here, we modeled tumor evolutionary trajectories during standard-of-care treatment using multi-omic single-cell analysis of a primary tumor sample, cor
Externí odkaz:
https://doaj.org/article/59df0ff277134bfbac1c8ddba33352e3
Autor:
Aristotelis Kotronoulas, Adrián López García de Lomana, Helga Kristín Einarsdóttir, Hilmar Kjartansson, Randolph Stone, Óttar Rolfsson
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2076 (2023)
Burn wound healing is a complex process orchestrated through successive biochemical events that span from weeks to months depending on the depth of the wound. Here, we report an untargeted metabolomics discovery approach to capture metabolic changes
Externí odkaz:
https://doaj.org/article/04c745511c3c40fbaafbe03fe346c4c7
Autor:
Selva Rupa Christinal Immanuel, Mario L. Arrieta-Ortiz, Rene A. Ruiz, Min Pan, Adrian Lopez Garcia de Lomana, Eliza J. R. Peterson, Nitin S. Baliga
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The ability of Mycobacterium tuberculosis (Mtb) to adopt heterogeneous physiological states underlies its success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenotypes are a major reason why the tuberculosi
Externí odkaz:
https://doaj.org/article/19f9589264d743d8835653ceef70aa7a
Autor:
Matthew A. Wall, Serdar Turkarslan, Wei-Ju Wu, Samuel A. Danziger, David J. Reiss, Mike J. Mason, Andrew P. Dervan, Matthew W. B. Trotter, Douglas Bassett, Robert M. Hershberg, Adrián López García de Lomana, Alexander V. Ratushny, Nitin S. Baliga
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-15 (2021)
Abstract Despite recent advancements in the treatment of multiple myeloma (MM), nearly all patients ultimately relapse and many become refractory to multiple lines of therapies. Therefore, we not only need the ability to predict which patients are at
Externí odkaz:
https://doaj.org/article/8be0e48133514e37800ac2c098080257
Autor:
Adrián López García de Lomana, Arnar Ingi Vilhjálmsson, Sarah McGarrity, Rósa Sigurðardóttir, Ósk Anuforo, Alexía Rós Viktorsdóttir, Aris Kotronoulas, Andreas Bergmann, Leifur Franzson, Haraldur Halldórsson, Hanne H. Henriksen, Charles E. Wade, Pär Ingemar Johansson, Óttar Rolfsson
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3162 (2022)
Disruption to endothelial cell homeostasis results in an extensive variety of human pathologies that are particularly relevant to major trauma. Circulating catecholamines, such as adrenaline and noradrenaline, activate endothelial adrenergic receptor
Externí odkaz:
https://doaj.org/article/cab676367f2749a5891e196438cbe300
Autor:
Adrián López García de Lomana, Ulrike Kusebauch, Arjun V. Raman, Min Pan, Serdar Turkarslan, Alan P. R. Lorenzetti, Robert L. Moritz, Nitin S. Baliga
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT When organisms encounter an unfavorable environment, they transition to a physiologically distinct, quiescent state wherein abundant transcripts from the previous active growth state continue to persist, albeit their active transcription is
Externí odkaz:
https://doaj.org/article/afdd33dca81b494c9cf8fa5d14208085
Autor:
Jacob J. Valenzuela, Adrián López García de Lomana, Allison Lee, E. V. Armbrust, Mónica V. Orellana, Nitin S. Baliga
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Diatoms account for 40% of marine primary production and their sensitivity to ocean acidification could have ecosystem-wide consequences. Here, the authors developed and applied a stress test, demonstrating that resilience of diatoms increases signif
Externí odkaz:
https://doaj.org/article/dd640bdc14314fa8b0027e5f4b4ae45b
Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells
Autor:
Thora Bjorg Sigmarsdottir, Sarah McGarrity, Adrián López García de Lomana, Aristotelis Kotronoulas, Snaevar Sigurdsson, James T. Yurkovich, Ottar Rolfsson, Olafur Eysteinn Sigurjonsson
Publikováno v:
Bioengineering, Vol 8, Iss 12, p 208 (2021)
Mesenchymal stromal cells (MSCs) are multipotent post-natal stem cells with applications in tissue engineering and regenerative medicine. MSCs can differentiate into osteoblasts, chondrocytes, or adipocytes, with functional differences in cells durin
Externí odkaz:
https://doaj.org/article/f9c9bba015c8413e9c2d45731bcca4fa