Zobrazeno 1 - 10
of 409
pro vyhledávání: '"Adrian J L Clark"'
Autor:
Adrian J L Clark, Simon Buckmaster
Publikováno v:
Endocrine Connections, Vol 10, Iss 11, Pp E3-E4 (2021)
One of the major concerns of any scientific journal is that the research it publishes should be reproducible. There have been many alarming estimates for the lack of reproducibility of work published in the biomedical sciences, which has led to wides
Externí odkaz:
https://doaj.org/article/8b12d1b60f804dba95fd6ec3926e7e38
Autor:
Tatiana V Novoselova, Peter J King, Leonardo Guasti, Louise A Metherell, Adrian J L Clark, Li F Chan
Publikováno v:
Endocrine Connections, Vol 8, Iss 7, Pp R122-R130 (2019)
The melanocortin-2-receptor (MC2R), also known as the ACTH receptor, is a critical component of the hypothalamic–pituitary–adrenal axis. The importance of MC2R in adrenal physiology is exemplified by the condition familial glucocorticoid deficien
Externí odkaz:
https://doaj.org/article/fbbcdc59c9ea49b5af7007e908e78ad9
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82989 (2013)
A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease. The mech
Externí odkaz:
https://doaj.org/article/c0cd203b1328412fb78b61adefcd1680
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9237 (2010)
Adverse events in pregnancy may 'programme' offspring for the later development of cardiovascular disease and hypertension. Previously, using a rodent model of programmed hypertension we have demonstrated the role of the renin-angiotensin system in t
Externí odkaz:
https://doaj.org/article/1c780f5766bb48539b367f8a5fe30606
Autor:
Jarl E. S. Wikberg, Jeffrey B. Tatro, Helgi Schiöth, Colin Pouton, Kathleen G. Mountjoy, Victor J. Hruby, Carrie Haskell-Luevano, Ira Gantz, Tung M. Fong, Sadaf Farooqi, Alex N. Eberle, Roger D. Cone, Adrian J. L. Clark, Biao-Xin Chai, Vanni Caruso
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogenous anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8e1dd58e2809f3d3ee0d5953002ec11
https://doi.org/10.2218/gtopdb/f38/2023.1
https://doi.org/10.2218/gtopdb/f38/2023.1
Autor:
Simon Buckmaster, Adrian J. L. Clark
Publikováno v:
Endocrine Connections
Endocrine Connections, Vol 10, Iss 11, Pp E3-E4 (2021)
Endocrine Connections, Vol 10, Iss 11, Pp E3-E4 (2021)
One of the major concerns of any scientific journal is that the research it publishes should be reproducible. There have been many alarming estimates for the lack of reproducibility of work published in the biomedical sciences, which has led to wides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22976b8b0fe19c68105959e9fe480ab8
https://pubmed.ncbi.nlm.nih.gov/34586081
https://pubmed.ncbi.nlm.nih.gov/34586081
Autor:
Helgi B. Schiöth, Alex N. Eberle, Sadaf Farooqi, Biaoxin Chai, Roger D. Cone, Colin W. Pouton, Jeffrey B. Tatro, Vanni Caruso, Jarl E. S. Wikberg, Adrian J. L. Clark, Tung M. Fong, Carrie Haskell-Luevano, Victor J. Hruby, Kathleen G. Mountjoy, Ira Gantz
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogenous anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad2ace4b81cb4715932d98c70bb99013
https://doi.org/10.2218/gtopdb/f38/2021.3
https://doi.org/10.2218/gtopdb/f38/2021.3
Autor:
Bruno Ferraz-de-Souza, Katrin Koehler, Elizabeth Crowne, Charles R. Buchanan, Nils Krone, Jeremy Allgrove, Edward T Andrews, P. K. Shah, N. Simon Thomas, Jenifer P. Suntharalingham, Tony Hulse, Angela Huebner, John C. Achermann, Adrian J. L. Clark, Peter E. Clayton, John Gregory, Tim Cheetham, Louise A. Metherell, Rathi Prasad, Avinaash Maharaj, M Guftar Shaikh, Peter C. Hindmarsh, Mehul T. Dattani, Catherine Roberts, Li F. Chan, Claire Hughes, Justin H Davies, Younus Qamar, Lin Lin, Federica Buonocore
Publikováno v:
Journal of the Endocrine Society
Context Although primary adrenal insufficiency (PAI) in children and young people is often due to congenital adrenal hyperplasia (CAH) or autoimmunity, other genetic causes occur. The relative prevalence of these conditions is poorly understood. Obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f105e0c59c3ea1cbc41e68b56ac8a909
http://europepmc.org/articles/PMC8266051
http://europepmc.org/articles/PMC8266051
Autor:
Ian A. Mason, Adrian J. L. Clark
Publikováno v:
Journal of Endocrinology. 251:E1-E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c0b762d665ddb0fb5030f8510bbf888
https://doi.org/10.1530/joe-21-0360
https://doi.org/10.1530/joe-21-0360
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 32:93-106
The melanocortin receptors (MCRs) and their accessory proteins (MRAPs) are involved in regulation of a diverse range of endocrine pathways. Genetic variants of these components result in phenotypic variation and disease. The MC1R is expressed in skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7309b9ccfedcc83874235ac9de0e266f
https://doi.org/10.1016/j.beem.2018.02.002
https://doi.org/10.1016/j.beem.2018.02.002