Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adrian Heaps"'
Autor:
Nirupma Kakkar, Charles McSharry, Adrian Heaps, S Hasan, Sharon Cookson, Iona Donnelly, Agnieszka Jozwik, Stephen Todryk, Stephen J. Bourke
Publikováno v:
Allergy. 75:1469-1473
Pigeon Fancier's Lung (PFL) is a form of Hypersensitivity Pneumonitis where lung pathology occurs due to an immune reaction to repeated inhalation of large amounts of feather-derived and droppings-derived dust [1]. The 1μm dust particles penetrate t
Autor:
Denise Darby, Adrian Heaps, Christopher Cockcroft, Jonathan Scargill, Marcus Yee Lu Sim, Tomaz Garcez, Clare Roisin Ellis
Publikováno v:
Annals of clinical biochemistry. 58(6)
Background SARS-CoV-2 serological testing has seen extensive academic and clinical use from investigating correlates of immunity to seroprevalence, convalescent plasma and vaccine trials. Interpretation of these studies will depend on robust validati
Autor:
Tariq El-Shanawany, Stephen Jolles, Rebecca L M Griffiths, Paul Williams, Emily Carne, Adrian Heaps, C. Selwood
Publikováno v:
International Archives of Allergy and Immunology. 172:215-223
Background: Allergy is diagnosed from typical symptoms, and tests are performed to incriminate the suspected precipitant. Skin prick tests (SPTs) are commonly performed, inexpensive, and give immediate results. Laboratory tests (ImmunoCAP) for serum
Autor:
Donna M. Muzny, Stephen Jolles, Asbjørg Stray-Pedersen, Ivan K. Chinn, Jolanta Chmielowiec, Malgorziata Borowiak, Emily M. Mace, Shalini N. Jhangiani, Megan Schmit, Silke Paust, Colin G. Steward, Mo Moody, Philip Connor, Richard A. Gibbs, Matilde I. Conte, Pinaki P. Banerjee, Rachel E. Bradley, Jordan S. Orange, Malini Mukherjee, Zeynep Coban Akdemir, Ryan M. Baxley, Ashley E. Pezzi, Adrian Heaps, James R. Lupski, Anja Katrin Bielinsky, Swetha Tatineni
Human natural killer cell deficiency (NKD) arises from inborn errors of immunity that lead to impaired NK cell development, function or both. Through the understanding of the biological perturbations in individuals with NKD, requirements for the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c924977c37186f489298988f38039d
Autor:
Adrian Heaps, Mo Moody, Grant Hayman, C. Selwood, E. R. Kaminski, Paul Williams, Amolak S Bansal, Sarah Deacock, Joe Unsworth, Nazira Sumar, Tariq El-Shanawany, Sara Carter, Stephen Jolles
Publikováno v:
Clinical and Experimental Immunology. 177:483-490
Summary A diagnosis of idiopathic anaphylaxis following a detailed clinical assessment remains very challenging for patients and clinicians. Risk reduction strategies such as allergen avoidance are not possible. This study investigated whether the (I
Autor:
Graham P. Taylor, Yuetsu Tanaka, Charles R. M. Bangham, Angelina J. Mosley, Becca Asquith, Angela R. McLean, Adrian Heaps
Publikováno v:
Retrovirology, Vol 2, Iss 1, p 75 (2005)
Retrovirology
Retrovirology
BackgroundHTLV-I causes the disabling inflammatory disease HAM/TSP: there is no vaccine, no satisfactory treatment and no means of assessing the risk of disease or prognosis in infected people. Like many immunopathological diseases with a viral etiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9495961d8ec938e9d2b49910b1c9945
https://doi.org/10.1186/1742-4690-2-75
https://doi.org/10.1186/1742-4690-2-75
Publikováno v:
Blood
Evidence from population genetics, gene expression microarrays, and assays of ex vivo T-cell function indicates that the cytotoxic T lymphocyte (CTL) response to human T-lymphotropic virus type 1 (HTLV-1) controls the level of HTLV-1 expression and t
Autor:
Charles R. M. Bangham, Vincenzo Cerundolo, Christopher Chiu, Adrian Heaps, Andrew J. McMichael, Margaret F. C. Callan
Publikováno v:
Blood. 109:1086-1094
Functional studies show that programming of CD8+ T cells occurs early after initial antigen encounter within as little as 2 hours. To define the molecular basis of these events, we transferred TCR transgenic T cells from F5 Rag−/− mice into naive
Autor:
Ceri Phillips, T. El Shanawany, Stephen Jolles, C. Selwood, Kerenza Hood, H. Sharp, P. Williams, Stephen Holding, S. Zouwail, R. Borrell, Mo Moody, Adrian Heaps
Publikováno v:
Clinical and Experimental Immunology
Summary Calculated globulin (total protein – albumin) is usually tested as part of a liver function test profile in both primary and secondary care and determines the serum globulin concentration, of which immunoglobulins are a major component. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fde7269aaf4845489f4487d34b6d3d2
https://cronfa.swan.ac.uk/Record/cronfa18272
https://cronfa.swan.ac.uk/Record/cronfa18272
Autor:
Mark D. Cossburn, Gillian Ingram, Neil Robertson, Trevor Pickersgill, Adrian Heaps, Stephen Jolles, Tariq El-Shanawany, Katharine Harding
Publikováno v:
Neurology. 80(1)
Objective: Alemtuzumab is potentially a highly effective treatment for relapsing multiple sclerosis (MS) acting via complement-mediated lysis of circulating lymphocytes. Variability in posttreatment lymphocyte recovery time is observed, with some pat