Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adrian Hapca"'
Autor:
Alvin Shrestha, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Christos Rossios, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307268 (2024)
IntroductionUnderstanding genetic contributors to sarcopenia (age-related loss of muscle strength and mass) is key to finding effective therapies. Variants of the bradykinin receptor 2 (BDKRB2) have been linked to athletic and muscle performance. The
Externí odkaz:
https://doaj.org/article/729f9642b39144fe86a84ce912c50d84
Autor:
The LACE study group, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M. Band, Tufail Bashir, Louise A. Burton, Vera Cvoro, Peter T. Donnan, Gordon W. Duncan, Jacob George, Adam L. Gordon, Celia L. Gregson, Adrian Hapca, Emily Henderson, Cheryl Hume, Thomas A. Jackson, Paul Kemp, Simon Kerr, Alixe Kilgour, Veronica Lyell, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C. Roberts, Christos Rossios, Avan A. Sayer, Karen T. Smith, Roy L. Soiza, Claire J. Steves, Allan D. Struthers, Deepa Sumukadas, Divya Tiwari, Julie Whitney, Miles D. Witham
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 858-871 (2022)
Abstract Background This trial aimed to determine the efficacy of leucine and/or perindopril in improving physical function in older people with sarcopenia. Methods Placebo‐controlled, parallel group, double‐blind, randomized two‐by‐two facto
Externí odkaz:
https://doaj.org/article/5f34d75a32554bc08ecdb7f05da3b12d
Autor:
Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Christos Rossios, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294330 (2023)
BackgroundAgeing is associated with changes in body composition including an overall reduction in muscle mass and a proportionate increase in fat mass. Sarcopenia is characterised by losses in both muscle mass and strength. Body composition and muscl
Externí odkaz:
https://doaj.org/article/c30fb2aff4ea4c5a9943bf38e3bcd800
Autor:
Christos Rossios, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292402 (2023)
BackgroundAngiotensin II (AII), has been suggested to promote muscle loss. Reducing AII synthesis, by inhibiting angiotensin converting enzyme (ACE) activity has been proposed as a method to inhibit muscle loss. The LACE clinical trial was designed t
Externí odkaz:
https://doaj.org/article/8651c39bcec645eeb9cc2a0bb488cd15
Autor:
Miles D. Witham, Marcus Achison, Terry J. Aspray, Alison Avenell, Margaret M. Band, Peter T. Donnan, Jacob George, Adrian Hapca, Cheryl Hume, Paul Kemp, Kristina Pilvinyte, Avan A. Sayer, Karen T. Smith, Allan D. Struthers, Deepa Sumukadas
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 2, Pp 93-102 (2021)
Abstract Background Sarcopenia is rarely diagnosed and is not recorded electronically in routine clinical care, posing challenges to trial recruitment. We describe the performance of four components of a strategy to efficiently recruit participants w
Externí odkaz:
https://doaj.org/article/e05c1ceddece461ba519a4e1b66344bf
Autor:
Miles D Witham, Simon Adamson, Alison Avenell, Margaret M Band, Tufail Bashir, Peter T Donnan, Jacob George, Adrian Hapca, Cheryl Hume, Paul Kemp, Emma McKenzie, Kristina Pilvinyte, Christos Rossios, Karen Smith, Allan D Struthers, Deepa Sumukadas
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 9, Iss 8 (2022)
Background: Angiotensin-converting enzyme inhibitors and leucine are promising potential treatments for sarcopenia. Neither has yet been tested in adequately powered randomised trials in patients with sarcopenia. Objectives: To determine the efficacy
Externí odkaz:
https://doaj.org/article/6cbf95e5be004745bf2b2a08f3047014
Autor:
Stephan U Dombrowski, Matthew McDonald, Marjon van der Pol, Mark Grindle, Alison Avenell, Paula Carroll, Eileen Calveley, Andrew Elders, Nicola Glennie, Cindy M Gray, Fiona M Harris, Adrian Hapca, Claire Jones, Frank Kee, Michelle C McKinley, Rebecca Skinner, Martin Tod, Pat Hoddinott
Publikováno v:
Public Health Research, Vol 8, Iss 11 (2020)
Background: In 2016, 26% of UK men were estimated to be obese. Systematic reviews suggest that few men engage in formal weight loss interventions that support weight reduction and improve health. Objective: To co-produce, with patient and public invo
Externí odkaz:
https://doaj.org/article/d68ffef3197b485ebfe4b8aa4c8af7b7
Autor:
Stephan U Dombrowski, Pat Hoddinott, Alison Avenell, Matthew McDonald, Marjon van der Pol, Mark Grindle, Paula Carroll, Eileen Calveley, Nicola Glennie, Fiona M Harris, Adrian Hapca, Michelle C McKinley, Rebecca Skinner, Martin Tod
Publikováno v:
BMJ Open, Vol 10, Iss 2 (2020)
ObjectivesTo examine the acceptability and feasibility of narrative text messages with or without financial incentives to support weight loss for men.DesignIndividually randomised three-arm feasibility trial with 12 months’ follow-up.SettingTwo sit
Externí odkaz:
https://doaj.org/article/d11e8e1a4419430ba0a7037b55e6a593
Autor:
Margaret M. Band, Deepa Sumukadas, Allan D. Struthers, Alison Avenell, Peter T. Donnan, Paul R. Kemp, Karen T. Smith, Cheryl L. Hume, Adrian Hapca, Miles D. Witham
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Sarcopenia (the age-related loss of muscle mass and function) is a major contributor to loss of mobility, falls, loss of independence, morbidity and mortality in older people. Although resistance training is effective in preventin
Externí odkaz:
https://doaj.org/article/85508a4fab3c4ffd9447ae32b01004c2
Autor:
Lewis Beer, Sarah Inglis, Amy Malaguti, Christopher Byrne, Christian Sharkey, Emma Robinson, Kirsty Gillings, Andrew Radley, Adrian Hapca, Brian Stephens, John Dillon
Publikováno v:
Journal of Viral Hepatitis. 29:646-653
Hepatitis C virus (HCV) treatment in people who inject drugs (PWID) is delivered within settings frequented by PWID, such as needle and syringe programs (NSP). The optimal direct-acting antiviral (DAA) dispensing regimen among NSP clients is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b6cf6e8f0148f76dbe5b1871a4a37d
https://doi.org/10.1111/jvh.13701
https://doi.org/10.1111/jvh.13701