Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adrian Häberli"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 53:24-28
An interaction product of aminotadalafil was isolated from an illegal health food product. The structure of the interaction product was elucidated by means of IR, NMR, and mass spectroscopy. The hitherto unknown compound was characterized as condensa
Publikováno v:
Helvetica Chimica Acta. 83:328-335
Autor:
Adrian Häberli, Hanspeter Pfander
Publikováno v:
Helvetica Chimica Acta. 82:696-706
The three apocarotenoids methyl (9Z)-8′-oxo-6,8′-diapocaroten-6-oate (2), methyl (9Z)-10′-oxo-6,10′-diapocaroten-6-oate (4), and methyl (9Z)-14′-oxo-6,14′-diapocaroten-6-oate (5), recently isolated from annatto, were synthesized. The key
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 22:1187-1189
We synthesized pyrrolidino-C-nucleosides, incorporated them into oligodeoxynucleotides and investigated their pairing properties. The thermal duplex and triplex stabilities were measured. While triplex formation is destabilized in the case of pyrroli
Publikováno v:
Angewandte Chemie. 113:3101-3103
Publikováno v:
Angewandte Chemie International Edition. 40:3012-3014
The stabilizing effect of a dG:dC base-pair can also be imparted to a DNA duplex by a non-hydrogen-bonding, non-shape-complementary nucleoside analogue when interstrand stacking interactions come into play. This is the case, for example, with dBP, wh
Autor:
Adrian Häberli, Christian J. Leumann
Publikováno v:
Organic letters. 3(3)
[figure: see text] A novel method for the synthesis of pyrrolidine C-nucleosides has been developed. The key step of the synthesis is the palladium(0)-mediated coupling of a disubstituted N-protected 2-pyrroline and 5-iodouracil. C-Nucleoside 14 and
Publikováno v:
Journal of Natural Products. 64:1254-1255
From the fruits of Asparagus falcatus a novel minor (Z)-carotenoid has been isolated and, on the basis of spectral data interpretation, characterized as (9Z)-capsanthin-5,6-epoxide [(9Z,3S,5R,6S,3'S,5'R)-5,6-epoxy-3,3'-dihydroxy-5,6-dihydro-beta,kapp
Publikováno v:
Organic & Biomolecular Chemistry. 3:1653
Pyrrolidino pseudo-C-nucleosides are isosteres of natural deoxynucleosides which are protonated at the pyrrolidino ring nitrogen under physiological conditions. As constituents of a triplex forming oligodeoxynucleotide (TFO), the positive charge is e
Publikováno v:
Helvetica Chimica Acta. 85:1327