Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Adrian Goodey"'
Autor:
Tom Reynders, Sylvie Rottey, Jay A. Grobler, Adrian Goodey, Liesbeth Haspeslagh, Stephanie E. Barrett, S. Aubrey Stoch, Ryan C. Vargo, Saijuan Zhang, Munjal Patel, Randolph P. Matthews, Marian Iwamoto
Publikováno v:
Nature Medicine. 27:1712-1717
Islatravir (MK-8591) is a highly potent type 1 human immunodeficiency virus (HIV-1) nucleoside reverse transcriptase translocation inhibitor with a long intracellular half-life that is in development for the prevention and treatment of HIV-1. We cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73fb991ae5d86fdf9c5e3e033f02be27
https://doi.org/10.1038/s41591-021-01479-3
https://doi.org/10.1038/s41591-021-01479-3
Autor:
Randolph P. Matthews, Xiaowei Zang, Stephanie E. Barrett, Athanas Koynov, Adrian Goodey, Tycho Heimbach, Vanessa L. Weissler, Carlien Leyssens, Tom Reynders, Zhiqing Xu, Sylvie Rottey, Ryan Vargo, Michael N. Robertson, S. Aubrey Stoch, Marian Iwamoto
Publikováno v:
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
Background:Islatravir (MK-8591) is a deoxyadenosine analog in development for the treatment and prevention of HIV-1 infection. An islatravir-eluting implant could provide an additional option for pre-exposure prophylaxis (PrEP).Setting:Previous data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2a4cf0e0e5f6e97e11d5eabdd11bab
https://pubmed.ncbi.nlm.nih.gov/36450129
https://pubmed.ncbi.nlm.nih.gov/36450129
Autor:
Randolph P, Matthews, Munjal, Patel, Stephanie E, Barrett, Liesbeth, Haspeslagh, Tom, Reynders, Saijuan, Zhang, Sylvie, Rottey, Adrian, Goodey, Ryan C, Vargo, Jay A, Grobler, S Aubrey, Stoch, Marian, Iwamoto
Publikováno v:
Nature medicine. 27(10)
Islatravir (MK-8591) is a highly potent type 1 human immunodeficiency virus (HIV-1) nucleoside reverse transcriptase translocation inhibitor with a long intracellular half-life that is in development for the prevention and treatment of HIV-1. We cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c08a9ddf7974514846b1a4c7e8dbd36
https://pubmed.ncbi.nlm.nih.gov/34741157
https://pubmed.ncbi.nlm.nih.gov/34741157
Publikováno v:
AAPS PharmSciTech. 21
Multi-stage cascade impactors (CI) are accepted for the determination of metrics of the drug mass aerodynamic particle size distributions (APSD) of aerosols emitted from orally inhaled products (OIPs). This is particularly important for products wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645eaff21b399335c2c1afaa78d3b509
https://doi.org/10.1208/s12249-020-01720-1
https://doi.org/10.1208/s12249-020-01720-1
Autor:
J . David Christopher, Terrence P. Tougas, Patrik U. Andersson, Adrian Goodey, Svetlana Lyapustina, Jolyon P. Mitchell, Rajni B. Patel, Jorge Quiroz
Publikováno v:
AAPS PharmSciTech. 18:3296-3306
This article reports on results from a two-lab, multiple impactor experiment evaluating the abbreviated impactor measurement (AIM) concept, conducted by the Cascade Impaction Working Group of the International Pharmaceutical Aerosol Consortium on Reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9f138c065011888a568fc4bf4610e2
https://doi.org/10.1208/s12249-017-0814-1
https://doi.org/10.1208/s12249-017-0814-1
Autor:
Adrian Goodey, Terrence P. Tougas, Jolyon P. Mitchell, Stephen W. Stein, Christopher Jd, William H. Doub, Svetlana Lyapustina, Patel Rb
Publikováno v:
AAPS PharmSciTech. 20
The multi-stage cascade impactor (CI) is the mainstay method for the determination of the aerodynamic particle size distribution (APSD) of aerosols emitted from orally inhaled products (OIPs). CIs are designed to operate at a constant flow rate throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a275cd89501374e3fd0d1e256ee3321d
https://doi.org/10.1208/s12249-019-1416-x
https://doi.org/10.1208/s12249-019-1416-x
Publikováno v:
Aerosol Science and Technology. 48:930-938
For nasally delivered medications, it is quite a challenge in the formulation development to characterize the deposition pattern in vivo. An in vitro nose model has been developed recently and adopted in our study to compare the deposition pattern of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6e06286440941884fd65d1d67b1706
https://doi.org/10.1080/02786826.2014.931566
https://doi.org/10.1080/02786826.2014.931566
Publikováno v:
AAPS PharmSciTech. 18(2)
The performance of two quality control (QC) tests for aerodynamic particle size distributions (APSD) of orally inhaled drug products (OIPs) is compared. One of the tests is based on the fine particle dose (FPD) metric currently expected by the Europe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792d21a645631a9b240c5fce18b3a37d
https://pubmed.ncbi.nlm.nih.gov/27068528
https://pubmed.ncbi.nlm.nih.gov/27068528
Autor:
John T. McDevitt, Jason B. Shear, Adrian Goodey, Young Soo Sohn, Dean P. Neikirk, Eric V. Anslyn
Publikováno v:
Sensor Letters. 2:69-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa892dcdbc79363c7e0220822b90c305
https://doi.org/10.1166/sl.2004.027
https://doi.org/10.1166/sl.2004.027
Autor:
Dean P. Neikirk, Adrian Goodey, Andrew D. Ellington, Mehnaaz F. Ali, John T. McDevitt, Marc D. Rodriguez, Romy Kirby
Publikováno v:
Analytical Chemistry. 75:4732-4739
The development of a chip-based sensor array composed of individually addressable agarose microbeads has been demonstrated for the rapid detection of DNA oligonucleotides. Here, a "plug and play" approach allows for the simple incorporation of variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0d5a652314573c2a5be6a35b157560
https://doi.org/10.1021/ac034106z
https://doi.org/10.1021/ac034106z