Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Adrian G. Zucco"'
Autor:
Christian M. Jensen, Junia C. Costa, Jens C. Nørgaard, Adrian G. Zucco, Bastian Neesgaard, Carsten U. Niemann, Sisse R. Ostrowski, Joanne Reekie, Birgit Holten, Anna Kalhauge, Michael A. Matthay, Jens D. Lundgren, Marie Helleberg, Kasper S. Moestrup
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Spatial resolution in existing chest x-ray (CXR)-based scoring systems for coronavirus disease 2019 (COVID-19) pneumonia is low, and should be increased for better representation of anatomy, and severity of lung involvement. An existing CXR-
Externí odkaz:
https://doaj.org/article/c6143a3479414b7992a3b36d75b64546
Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning
Autor:
Adrian G. Zucco, Rudi Agius, Rebecka Svanberg, Kasper S. Moestrup, Ramtin Z. Marandi, Cameron Ross MacPherson, Jens Lundgren, Sisse R. Ostrowski, Carsten U. Niemann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Interpretable risk assessment of SARS-CoV-2 positive patients can aid clinicians to implement precision medicine. Here we trained a machine learning model to predict mortality within 12 weeks of a first positive SARS-CoV-2 test. By leveragin
Externí odkaz:
https://doaj.org/article/ab4930ae24b141eaa08fd86ddee41197
Autor:
Kirstine K. Rasmussen, Quenia dos Santos, Cameron Ross MacPherson, Adrian G. Zucco, Lars Klingen Gjærde, Emma E. Ilett, Isabelle Lodding, Marie Helleberg, Jens D. Lundgren, Susanne D. Nielsen, Susanne Brix, Henrik Sengeløv, Daniel D. Murray
Publikováno v:
Metabolites, Vol 13, Iss 9, p 968 (2023)
Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation (aHSCT) predisposes one to an elevated risk of cytomegalovirus (CMV) infection. Changes in metabolism have been associated with adverse outcomes, and in this study,
Externí odkaz:
https://doaj.org/article/c0f19a57aa95435990307037ca22b5cd
Autor:
Kasper S Moestrup, Joanne Reekie, Adrian G Zucco, Tomas Ø Jensen, Jens-Ulrik S Jensen, Lothar Wiese, Sisse R Ostrowski, Carsten U Niemann, Cameron MacPherson, Jens Lundgren, Marie Helleberg
Publikováno v:
Clinical Infectious Diseases. 76:e82-e89
Background Many interventional in-patient coronavirus disease 2019 (COVID-19) trials assess primary outcomes through day 28 post-randomization. Since a proportion of patients experience protracted disease or relapse, such follow-up period may not ful
Autor:
Adrian G. Zucco, Marc Bennedbæk, Christina Ekenberg, Migle Gabrielaite, Preston Leung, Mark N. Polizzotto, Virginia Kan, Daniel D. Murray, Jens D. Lundgren, Cameron R. Macpherson
Publikováno v:
AIDS.
Autor:
Daniel D. Murray, Birgit Grund, Cameron R. MacPherson, Christina Ekenberg, Adrian G. Zucco, Joanne Reekie, Lourdes Dominguez-Dominguez, Preston Leung, Dahlene Fusco, Julien Gras, Jan Gerstoft, Marie Helleberg, Álvaro H. Borges, Mark N. Polizzotto, Jens D. Lundgren
Publikováno v:
Murray, D D, Grund, B, Macpherson, C R, Ekenberg, C, Zucco, A G, Reekie, J, Dominguez-Dominguez, L, Leung, P, Fusco, D, Gras, J, Gerstoft, J, Helleberg, M, Borges, Á H, Polizzotto, M N & Lundgren, J D 2023, ' Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV ', AIDS, vol. 37, no. 3, pp. 379-387 . https://doi.org/10.1097/QAD.0000000000003427
Introduction:Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the human gene ten-eleven methylcytosine dioxygenase 2 (TET2) in modulating HIV-pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b5b50e2d72d6a0411ea9f4545e2dec
https://curis.ku.dk/portal/da/publications/association-between-teneleven-methylcytosine-dioxygenase-2-genetic-variation-and-viral-load-in-people-with-hiv(a9044e18-952b-4359-af38-2036ff34020a).html
https://curis.ku.dk/portal/da/publications/association-between-teneleven-methylcytosine-dioxygenase-2-genetic-variation-and-viral-load-in-people-with-hiv(a9044e18-952b-4359-af38-2036ff34020a).html
Autor:
Kasper S, Moestrup, Joanne, Reekie, Adrian G, Zucco, Tomas Ø, Jensen, Jens Ulrik S, Jensen, Lothar, Wiese, Sisse R, Ostrowski, Carsten U, Niemann, Cameron, MacPherson, Jens, Lundgren, Marie, Helleberg
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
Many interventional in-patient COVID-19 trials assess primary outcomes through day 28 post-randomization. Since a proportion of patients experience protracted disease or relapse, such follow-up period may not fully capture the course of the disease,
Autor:
Dan Turner, Huldrych F. Günthard, Mark N. Polizzotto, Rasmus L. Marvig, Sandra E. Safo, James D. Neaton, Migle Gabrielaite, Giota Touloumi, Daniel D Murray, Adrian G. Zucco, Christina Ekenberg, H. Clifford Lane, Alejandro Arenas-Pinto, Linos Vandekerckhove, Virginia L. Kan, Marc Bennedbæk, Jens D Lundgren
Publikováno v:
Gabrielaite, M, Bennedbæk, M, Zucco, A G, Ekenberg, C, Murray, D D, Kan, V L, Touloumi, G, Vandekerckhove, L, Turner, D, Neaton, J, Clifford Lane, H, Safo, S, Arenas-Pinto, A, Polizzotto, M N, Günthard, H F, Lundgren, J D & Marvig, R L 2021, ' Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity ', Journal of Infectious Diseases, vol. 224, no. 12, pp. 2053-2063 . https://doi.org/10.1093/infdis/jiab253
J Infect Dis
J Infect Dis
BackgroundUnderstanding the genetic interplay between human hosts and infectious pathogens is crucial for how we interpret virulence factors. Here, we tested for associations between HIV and host genetics, and interactive genetic effects on viral loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ca9c0e187f83dc25bde01e8e7f6c4a
https://curis.ku.dk/portal/da/publications/human-immunotypes-impose-selection-on-viral-genotypes-through-viral-epitope-specificity(877c7699-abfe-4433-b460-b947a95ac60e).html
https://curis.ku.dk/portal/da/publications/human-immunotypes-impose-selection-on-viral-genotypes-through-viral-epitope-specificity(877c7699-abfe-4433-b460-b947a95ac60e).html
Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning
Autor:
Ramtin Z. Marandi, Carsten Utoft Niemann, Sisse R. Ostrowski, Rudi Agius, Cameron Ross MacPherson, Rebecka Svanberg, Jens D Lundgren, Kasper Sommerlund Moestrup, Adrian G. Zucco
Publikováno v:
Zucco, A G, Agius, R, Svanberg, R, Moestrup, K S, Marandi, R Z, MacPherson, C R, Lundgren, J, Ostrowski, S R & Niemann, C U 2022, ' Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning ', Scientific Reports, vol. 12, 13879 . https://doi.org/10.1038/s41598-022-17953-y
Interpretable risk assessment of SARS-CoV-2 positive patients can aid clinicians to implement precision medicine. Here we trained a machine learning model to predict mortality within 12 weeks of a first positive SARS-CoV-2 test. By leveraging data on
Autor:
Kasper S Moestrup, Adrian G Zucco, Joanne Reekie, Cameron MacPherson, Sisse R Otrowski, Carsten Utoft Niemann, Jens Lundgren, Marie Helleberg
Publikováno v:
Open Forum Infectious Diseases
Background Several interventional Coronavirus Disease 2019 (COVID-19) studies assess outcomes at day 28, but this follow-up time can be too short, since COVID-19 often cause protracted disease. Further, data on mortality and readmissions after discha