Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adrian G. Flores"'
Atox1 Contains Positive Residues that Mediate Membrane Association and Aid Subsequent Copper Loading
Autor:
Vinzenz M. Unger, Adrian G. Flores
Publikováno v:
The Journal of Membrane Biology. 246:903-913
Copper chaperones bind intracellular copper and ensure proper trafficking to downstream targets via protein-protein interactions. In contrast to the mechanisms of copper binding and transfer to downstream targets, the mechanisms of initial copper loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ee2086bfe4415be9aaf6f694a67d9a
https://doi.org/10.1007/s00232-013-9592-1
https://doi.org/10.1007/s00232-013-9592-1
Autor:
Mary Frances McMullin, Terence R.J. Lappin, Frank S. Lee, Quan Zhao, Patrick H. Maxwell, Melanie J. Percy, Claire N. Harrison, Adrian G. Flores
Publikováno v:
Proceedings of the National Academy of Sciences. 103:654-659
The number of red blood cells is normally tightly regulated by a classic homeostatic mechanism based on oxygen sensing in the kidney. Decreased oxygen delivery resulting from anemia induces the production of erythropoietin, which increases red cell p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bce88e1456fe409a1c0ba435d959499
https://doi.org/10.1073/pnas.0508423103
https://doi.org/10.1073/pnas.0508423103
Autor:
D Mangoura, Y Sun, D. Singh, David H. Gutmann, M Ahmed, Adrian G. Flores, G Vallianatos, C Li
Publikováno v:
Oncogene. 25:735-745
Children with neurofibromatosis (NF1) typically develop central nervous system (CNS) abnormalities, including aberrant proliferation of astrocytes and formation of benign astrocytomas. The NF1 gene encodes neurofibromin, a Ras-GAP, highly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bdce7f36975ea257da63610ae8ec57
https://doi.org/10.1038/sj.onc.1209113
https://doi.org/10.1038/sj.onc.1209113
Publikováno v:
The FASEB Journal. 28
Critical for cellular function, ions of the transition metal copper need to reach multiple specific destinations inside cells in an efficient manner. That they do is taken for granted. Yet, how exactly does an ion of 11A3 find binding sites of ~1000A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc7c7a9f04836f6be057d79b3e8ea36
https://doi.org/10.1096/fasebj.28.1_supplement.360.3
https://doi.org/10.1096/fasebj.28.1_supplement.360.3
Publikováno v:
Current topics in membranes. 69
Owing to their redox and coordination chemistry copper ions play essential roles in cellular function. Research over the past 20 years has shed much light on the biochemistry of copper homeostasis, and the emergence of high-resolution crystal structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ffc49493ccfde4058d9e34f9a3375b6
https://pubmed.ncbi.nlm.nih.gov/23046648
https://pubmed.ncbi.nlm.nih.gov/23046648
Owing to their redox and coordination chemistry copper ions play essential roles in cellular function. Research over the past 20 years has shed much light on the biochemistry of copper homeostasis, and the emergence of high-resolution crystal structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd37094eb8bc9060d0544f31f8f05356
https://doi.org/10.1016/b978-0-12-394390-3.00004-5
https://doi.org/10.1016/b978-0-12-394390-3.00004-5
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry
Copper ions are essential for life because of their ability to support a number of cellular processes, ranging from respiration to the synthesis of connective tissue. At the same time, the redox and coordination chemistry of copper can be toxic to ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51beeb0384c3969cd3d104184d3df8a8
https://doi.org/10.1002/9781119951438.eibc2121
https://doi.org/10.1002/9781119951438.eibc2121