Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adrian G. Cadar"'
Autor:
Santiago Angaramo, Sharon Kam, Jacqueline Antoun, Manasa R Bhatta, Pauleatha Diggs Bonds, Adrian G Cadar, Valentine U Chukwuma, Patrick J Donegan, Zachary Feldman, Alan Z Grusky, Veerain K Gupta, Jeremy B Hatcher, Jaclyn Lee, Natalia G Morales, Erin N Vrana, Bronson C Wessinger, Michael Z Zhang, Michael J Fowler, Chase D Hendrickson
Publikováno v:
BMJ Open Quality, Vol 11, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/a0f1921edb6a49b4b51c9b53655f8111
Autor:
Young Wook Chun, Matthew Miyamoto, Charles H. Williams, Leif R. Neitzel, Maya Silver-Isenstadt, Adrian G. Cadar, Daniela T. Fuller, Daniel C. Fong, Hanhan Liu, Robert Lease, Sungseek Kim, Mikako Katagiri, Matthew D. Durbin, Kuo-Chen Wang, Tromondae K. Feaster, Calvin C. Sheng, M. Diana Neely, Urmila Sreenivasan, Marcia Cortes-Gutierrez, Aloke V. Finn, Rachel Schot, Grazia M.S. Mancini, Seth A. Ament, Kevin C. Ess, Aaron B. Bowman, Zhe Han, David P. Bichell, Yan Ru Su, Charles C. Hong
Publikováno v:
Circulation, 147(17), 1291-1303. Lippincott Williams & Wilkins
Background: During cardiomyocyte maturation, the centrosome, which functions as a microtubule organizing center in cardiomyocytes, undergoes dramatic structural reorganization where its components reorganize from being localized at the centriole to t
Autor:
Sharon Kam, Santiago Angaramo, Jacqueline Antoun, Manasa R Bhatta, Pauleatha Diggs Bonds, Adrian G Cadar, Valentine U Chukwuma, Patrick J Donegan, Zachary Feldman, Alan Z Grusky, Veerain K Gupta, Jeremy B Hatcher, Jaclyn Lee, Natalia G Morales, Erin N Vrana, Bronson C Wessinger, Michael Z Zhang, Michael J Fowler, Chase D Hendrickson
Publikováno v:
BMJ Open Quality
BMJ Open Quality, Vol 11, Iss 1 (2022)
BMJ Open Quality, Vol 11, Iss 1 (2022)
BackgroundAnnual albuminuria screening detects the early stages of nephropathy in individuals with diabetes. Because early detection of albuminuria allows for interventions that lower the risk of developing chronic kidney disease, guidelines recommen
Autor:
Chee Chew Lim, Michael Gotthardt, Lili Wang, Joseph A. Balsamo, Charles C. Hong, Dan M. Roden, Bjorn C. Knollmann, Tromondae K. Feaster, Young-Jae Nam, Kevin R. Bersell, Young Wook Chun, Adrian G. Cadar, TingTing Hong, Zhentao Zhang
Publikováno v:
Am J Physiol Cell Physiol
Fluorescence recovery after photobleaching (FRAP) has been useful in delineating cardiac myofilament biology, and innovations in fluorophore chemistry have expanded the array of microscopic assays used. However, one assumption in FRAP is the irrevers
Publikováno v:
Pediatric research
The study of disease pathophysiology has long relied on model systems, including animal models and cultured cells. In 2006, Shinya Yamanaka achieved a breakthrough by reprogramming somatic cells into induced pluripotent stem cells (iPSCs). This revol
Autor:
Lili Wang, Kyungsoo Kim, Huan He, Dmytro O. Kryshtal, Jose R. Pinto, Bjorn C. Knollmann, Adrian G. Cadar, Kevin R. Bersell, Shan Parikh
Publikováno v:
Journal of Molecular and Cellular Cardiology. 114:320-327
Background Mutations in cardiac troponin T (TnT) are linked to increased risk of ventricular arrhythmia and sudden death despite causing little to no cardiac hypertrophy. Studies in mice suggest that the hypertrophic cardiomyopathy (HCM)-associated T
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:1947-1953
From a high content in vivo screen for modulators of developmental patterning in embryonic zebrafish, we previously identified eggmanone (EGM1, 3) as a Hedgehog (Hh) signaling inhibitor functioning downstream of Smoothened. Phenotypic optimization st
Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, significant advances have been made in the basic science and translational realms to better understand human diseases at the cellular level and to develop new therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ed403e49d47516cfa25a69c43d05ec
https://doi.org/10.1016/b978-0-12-801238-3.10919-5
https://doi.org/10.1016/b978-0-12-801238-3.10919-5
Publikováno v:
Biochemical and Biophysical Research Communications. 453:185-191
Titin is the largest known protein and a critical determinant of myofibril elasticity and sarcomere structure in striated muscle. Accumulating evidence that mRNA transcripts are post-transcriptionally regulated by specific motifs located in the flank
Publikováno v:
Current Protocols in Stem Cell Biology
This unit describes the published Matrigel mattress method. Briefly, we describe the preparation of the mattress, replating of the human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) on the Matrigel mattress, and hiPSC-CM mattress m