Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Adrian F, Gombart"'
Autor:
Karim M. Aloul, Josefine Eilsø Nielsen, Erwin B. Defensor, Jennifer S. Lin, John A. Fortkort, Mehrdad Shamloo, Jeffrey D. Cirillo, Adrian F. Gombart, Annelise E. Barron
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 is characterized by hyperactivation by inflammatory cytokines and recruitment of macrophages, neutrophils, and other immune cells, all hallmarks of a strong inflammatory response that can lead to severe complications and multi-organ damage.
Externí odkaz:
https://doaj.org/article/f3906552da204973bf89516b1deb37af
Autor:
Yang Zhang, Gerd Bobe, Cristobal L Miranda, Malcolm B Lowry, Victor L Hsu, Christiane V Lohr, Carmen P Wong, Donald B Jump, Matthew M Robinson, Thomas J Sharpton, Claudia S Maier, Jan F Stevens, Adrian F Gombart
Publikováno v:
eLife, Vol 10 (2021)
We previously reported xanthohumol (XN), and its synthetic derivative tetrahydro-XN (TXN), attenuates high-fat diet (HFD)-induced obesity and metabolic syndrome in C57Bl/6J mice. The objective of the current study was to determine the effect of XN an
Externí odkaz:
https://doaj.org/article/2429acd383fb4e10be829a3c44468c2f
Autor:
Philip C. Calder, Mette M. Berger, Adrian F. Gombart, Grace A. McComsey, Adrian R. Martineau, Manfred Eggersdorfer
Publikováno v:
Vaccines, Vol 10, Iss 4, p 568 (2022)
The world has entered the third year of the coronavirus disease 2019 (COVID-19) pandemic. Vaccination is the primary public health strategy to protect against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in addition to
Externí odkaz:
https://doaj.org/article/1ec850b031594604b0755c3748b6a057
Autor:
Yajuan Su, Gitali Ganguli-Indra, Nilika Bhattacharya, Isabelle E. Logan, Arup K. Indra, Adrian F. Gombart, Shannon L. Wong, Jingwei Xie
Publikováno v:
Molecular Pharmaceutics. 19:974-984
Publikováno v:
Aging Cell, 22(1):e13758. Wiley
Autor:
Isabelle E. Logan, Gerd Bobe, Cristobal L. Miranda, Stephany Vasquez-Perez, Jaewoo Choi, Malcolm B. Lowry, Thomas J. Sharpton, Andrey Morgun, Claudia S. Maier, Jan F. Stevens, Natalia Shulzhenko, Adrian F. Gombart
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 520 (2020)
A calorie-dense diet is a well-established risk factor for obesity and metabolic syndrome (MetS), whereas the role of the intestinal microbiota (IMB) in the development of diet-induced obesity (DIO) is not completely understood. To test the hypothesi
Externí odkaz:
https://doaj.org/article/178af5bf71a84aa290ad54d28a43a9f7
Autor:
Yajuan Su, Navatha Shree Sharma, Johnson V. John, Gitali Ganguli‐Indra, Arup K. Indra, Adrian F. Gombart, Jingwei Xie
Publikováno v:
Advanced Healthcare Materials. 11
Exosomes show great potential in diagnostic and therapeutic applications. Inspired by the human innate immune defense, herein, we report engineered exosomes derived from monocytic cells treated with immunomodulating compounds 1α,25-dihydroxyvitamin
Autor:
Claudia S. Maier, Adrian F. Gombart, Jan F. Stevens, Yuan Jiang, Jeff Morré, Jay Kirkwood, Samanthi I. Wickramasekara, LeeCole Legette, Fereshteh Zandkarimi
Publikováno v:
Metabolites, Vol 3, Iss 3, Pp 701-717 (2013)
This study reports on the use of traveling wave ion mobility quadrupole time-of-flight (ToF) mass spectrometry for plasma metabolomics. Plasma metabolite profiles of obese Zucker fa/fa rats were obtained after the administration of different oral dos
Externí odkaz:
https://doaj.org/article/860bd1d330444a9e93666e52533ff51a
Autor:
Manfred Eggersdorfer, Mette M Berger, Philip C Calder, Adrian F Gombart, Emily Ho, Alessandro Laviano, Simin N Meydani
Publikováno v:
Advances in nutrition (Bethesda, Md.). 13(5)
The immune system is weakened by advancing age, often referred to as immunosenescence, increasing the vulnerability to, and frequently the severity of, infectious diseases in older people. This has become very apparent in the current coronavirus dise
Autor:
Liangpeng Ge, Shixuan Chen, Hongjun Wang, Yan Cheng, Jingwei Xie, Adrian F. Gombart, Larisa Y. Poluektova, Santhi Gorantla
Publikováno v:
Acta Biomaterialia. 97:187-199
Vitamin D3 modulates immune response, induces endogenous antimicrobial peptide production, and enhances innate immunity to defend against infections. These findings suggest that incorporating vitamin D3 into medical devices or scaffolds could positiv