Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adrian D. Sproul"'
Publikováno v:
Molecular Pharmacology. 64:650-658
The molecular mechanisms that couple agonist binding to the gating of Cys-loop ionotropic receptors are not well understood. The crystal structure of the acetylcholine (ACh) binding protein has provided insights into the structure of the extracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a6219a9bcddfcbe475416aed54529c
https://doi.org/10.1124/mol.64.3.650
https://doi.org/10.1124/mol.64.3.650
Publikováno v:
Brain Hypoxia and Ischemia ISBN: 9781603275781
The Na+/K+-ATPase is a transmembrane protein that serves as the primary electrogenic ion transporter in the plasma membrane of all mammalian cells. In addition to this critical ubiquitous function, the Na+/K+-ATPase is also essential for several impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de184aa866f51f575b144ef75dd9c0e3
https://doi.org/10.1007/978-1-60327-579-8_4
https://doi.org/10.1007/978-1-60327-579-8_4
Publikováno v:
Molecular pharmacology. 70(1)
alpha-7 Nicotinic acetylcholine receptors (AChRs) exhibit a positive modulation by divalent cations similar to that observed in other AChRs. In the chick alpha7 AChR, this modulation involves a conserved glutamate in loop 9 (Glu172) that undergoes ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338994acc97fff6825628b10253ca609
https://pubmed.ncbi.nlm.nih.gov/16641314
https://pubmed.ncbi.nlm.nih.gov/16641314
Publikováno v:
American journal of physiology. Cell physiology. 283(5)
Neuronal α7 nicotinic ACh receptors (nAChRs) are permeable to and modulated by Ca2+, Ba2+, and Sr2+. These permeant divalent cations interact with slowly desensitizing L247T α7nAChRs to increase the potency and maximal efficacy of ACh, increase the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0547cef1c3287f6ec9e9adfc203bdbfc
https://pubmed.ncbi.nlm.nih.gov/12372806
https://pubmed.ncbi.nlm.nih.gov/12372806