A phase III randomized, open-label, non-inferiority clinical trial comparing liquid and lyophilized formulations of oral live attenuated human rotavirus vaccine (HRV) in Indian infants

Autor: Catherine Cohet, Brigitte Cheuvart, Leentje Moerman, Dan Bi, Adrian Caplanusi, Mallesh Kariyappa, Sanjay Lalwani, Monjori Mitra, Amita Sapru, Shruti Saha, P.V. Varughese, Rajeev Zachariah Kompithra, Sanjay Gandhi

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 17, Iss 11, Pp 4646-4653 (2021)

The human rotavirus vaccine (HRV; Rotarix, GSK) is available as liquid (Liq) and lyophilized (Lyo) formulations, but only Lyo HRV is licensed in India. In this phase III, randomized, open-label trial (NCT02141204), healthy Indian infants aged 6–10

Externí odkaz: https://doaj.org/article/5d35f76d2617450b9901c97811e1abfb

A phase III randomized, open-label, non-inferiority clinical trial comparing liquid and lyophilized formulations of oral live attenuated human rotavirus vaccine (HRV) in Indian infants

Autor: Rajeev Zachariah Kompithra, Dan Bi, Amita Sapru, Adrian Caplanusi, Shruti Saha, Leentje Moerman, Brigitte Cheuvart, Sanjay Gandhi, Mallesh Kariyappa, Sanjay Lalwani, Catherine Cohet, Monjori Mitra, P.V. Varughese

Publikováno v: Human Vaccines & Immunotherapeutics. 17:4646-4653

The human rotavirus vaccine (HRV; Rotarix, GSK) is available as liquid (Liq) and lyophilized (Lyo) formulations, but only Lyo HRV is licensed in India. In this phase III, randomized, open-label trial (NCT02141204), healthy Indian infants aged 6-10 we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86bdf4be4266e2b38f3c6d5badc7ee0
https://doi.org/10.1080/21645515.2021.1960136

Immunogenicity and Safety of a Measles-Mumps-Rubella Vaccine Administered as a First Dose to Children Aged 12 to 15 Months: A Phase III, Randomized, Noninferiority, Lot-to-Lot Consistency Study

Autor: John A. Fling, Kwabena O. Sarpong, David Speicher, Keith P. Ramsey, Stephane Carryn, Peter E. Silas, Juan Carlos Tinoco, Maribel Campos, Michael Povey, Anitta Ahonen, Tiina Korhonen, Adrian Caplanusi, Nicola P. Klein, Carmen Baccarini, Paul Gillard, Leonard B. Weiner, Gary S. Marshall, Ouzama Henry, Javier Díez-Domingo, Iona Munjal, Mercedes Macias Parra, Remon Abu-Elyazeed, Timo Vesikari, Christopher Peltier

Publikováno v: Journal of the Pediatric Infectious Diseases Society
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Background MMR II (M-M-R II [Merck & Co, Inc.]) is currently the only measles, mumps, and rubella (MMR) vaccine licensed in the United States. A second MMR vaccine would mitigate the potential risk of vaccine supply shortage or delay. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cc8473dd88bee25a9bb9a3b28c02b3
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3323

Safety and persistence of the humoral and cellular immune responses induced by 2 doses of an AS03-adjuvanted A(H1N1)pdm09 pandemic influenza vaccine administered to infants, children and adolescents: Two open, uncontrolled studies

Autor: Juan C. Tejedor, Philippe Moris, Ilse Dieussaert, Karl Walravens, Jose Manuel Merino, Felix Omeñaca, Alfonso Carmona, Paul Gillard, José Garcia-Sicilia, Javier Arístegui, Vinod Bambure, Pilar García-Corbeira, Adrian Caplanusi

Publikováno v: Human Vaccines & Immunotherapeutics
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

In children, 2 AS03-adjuvanted A(H1N1)pdm09 vaccine doses given 21 days apart were previously shown to induce a high humoral immune response and to have an acceptable safety profile up to 42 days following the first vaccination. Here, we analyzed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5b0232bed10e97f170e4161ae7e767
http://europepmc.org/articles/PMC4635840

Images in Cellular/Molecular Medicine: Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules

Autor: Kleber Simônio Parreira, Pierre J. Courtoy, B. Marien, Olivier Devuyst, P. Van Der Smissen, Adrian Caplanusi, W. Rezende Lima, P. De Diesbach

Publikováno v: Journal of Cellular and Molecular Medicine. 12:351-354

Understanding renal function requires one to integrate the structural complexity of kidney nephrons and the dynamic nature of their cellular processes. Multi-photon fluorescence microscopy is a state-of-the-art imaging technique for in vivo analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ceaed47206828044f80d5616118ba2f
https://doi.org/10.1111/j.1582-4934.2007.00192.x