Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Adrian C. Eddy"'
Autor:
Samuel Speaks, Matthew I. McFadden, Ashley Zani, Abigail Solstad, Steve Leumi, Jack E. Roettger, Adam D. Kenney, Hannah Bone, Lizhi Zhang, Parker J. Denz, Adrian C. Eddy, Amal O. Amer, Richard T. Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function of the inflammasome-activated, pore-forming protein gasdermin D (GSDMD) during in
Externí odkaz:
https://doaj.org/article/1bdb4d643c5340eaab89b6eb41184ba9
Autor:
Farzana Liakath Ali, Hang-Soo Park, Analea Beckman, Adrian C. Eddy, Samar Alkhrait, Mohammad Mousaei Ghasroldasht, Ayman Al-Hendy, Omer Raheem
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 60 (2023)
Currently, there is no viable option for fertility preservation in prepubertal boys. Experimentally, controlled vitrification of testicular tissue has been evaluated and found to cause potential structural damage to the spermatogonial stem cell (SSC)
Externí odkaz:
https://doaj.org/article/376ccd7de6c743efaa2f0c525ac0b46d
Autor:
Guoli Shi, Abhilash I. Chiramel, Tiansheng Li, Kin Kui Lai, Adam D. Kenney, Ashley Zani, Adrian C. Eddy, Saliha Majdoul, Lizhi Zhang, Tirhas Dempsey, Paul A. Beare, Swagata Kar, Jonathan W. Yewdell, Sonja M. Best, Jacob S. Yount, Alex A. Compton
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in immunocompromised individuals is associated with prolonged virus shedding and evolution of viral variants. Rapamycin and its analogs (rapalogs, including everolimus, temsirolim
Externí odkaz:
https://doaj.org/article/54c02ef4c7e14f2d8fd82a8b248817d9
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-11 (2018)
Abstract Preeclampsia is a pregnancy-induced hypertensive disorder resulting from abnormal placentation, which causes factors such as sFlt-1 to be released into the maternal circulation. Though anti-hypertensive drugs and magnesium sulfate can be giv
Externí odkaz:
https://doaj.org/article/b66bb0f94c3944f5878e37f4ae11ce7a
Autor:
Samuel Speaks, Ashley Zani, Abigail Solstad, Adam Kenney, Matthew I. McFadden, Lizhi Zhang, Adrian C. Eddy, Amal O. Amer, Richard Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Influenza virus activates cellular inflammasome pathways, which can be either beneficial or detrimental to infection outcomes. Here, we investigated the role of the inflammasome-activated pore-forming protein gasdermin D (GSDMD) during infection. Abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::132b8f52880564fbf55e8b18b5674644
https://doi.org/10.1101/2023.03.08.531787
https://doi.org/10.1101/2023.03.08.531787
Autor:
Adam D Kenney, Ashley Zani, Jeffrey Kawahara, Adrian C Eddy, Xiao‐Liang Wang, KC Mahesh, Mijia Lu, Jeronay Thomas, Jacob E Kohlmeier, Mehul S Suthar, Emily A Hemann, Jianrong Li, Mark E Peeples, Luanne Hall‐Stoodley, Adriana Forero, Chuanxi Cai, Jianjie Ma, Jacob S Yount
Publikováno v:
EMBO reports. 24
Autor:
Mostafa M. Eltobgy, Ashley Zani, Adam D. Kenney, Shady Estfanous, Eunsoo Kim, Asmaa Badr, Cierra Carafice, Kylene Daily, Owen Whitham, Maciej Pietrzak, Amy Webb, Jeffrey Kawahara, Adrian C. Eddy, Parker Denz, Mijia Lu, Mahesh KC, Mark E. Peeples, Jianrong Li, Jian Zhu, Jianwen Que, Richard Robinson, Oscar Rosas Mejia, Rachael E. Rayner, Luanne Hall-Stoodley, Stephanie Seveau, Mikhail A. Gavrilin, Xiaoli Zhang, Jeronay Thomas, Jacob E. Kohlmeier, Mehul S. Suthar, Eugene Oltz, Andrea Tedeschi, Frank H. Robledo-Avila, Santiago Partida-Sanchez, Emily A. Hemann, Eman Abdelrazik, Adriana Forero, Shahid M. Nimjee, Prosper N. Boyaka, Estelle Cormet-Boyaka, Jacob S. Yount, Amal O. Amer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain e
Autor:
John Aaron Howell, Adrian C Eddy, Erin B. Taylor, Heather Chapman, Gene L. Bidwell, Fakhri Mahdi, Eric M. George
Publikováno v:
Hypertension
Preeclampsia is a hypertensive disorder of pregnancy that causes significant acute and long-term risk to the mother and the baby. The multifaceted maternal syndrome is driven by overproduction of circulating anti-angiogenic factors, widespread inflam
Autor:
Ashley, Zani, Adam D, Kenney, Jeffrey, Kawahara, Adrian C, Eddy, Xiao-Liang, Wang, Mahesh, Kc, Mijia, Lu, Emily A, Hemann, Jianrong, Li, Mark E, Peeples, Luanne, Hall-Stoodley, Adriana, Forero, Chuanxi, Cai, Jianjie, Ma, Jacob S, Yount
Publikováno v:
bioRxiv
Interferon-induced transmembrane protein 3 (IFITM3) is a host antiviral protein that alters cell membranes to block fusion of viruses. Published reports have identified conflicting pro- and antiviral effects of IFITM3 on SARS-CoV-2 in cultured cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c605546b9b548b2bfa6c544d71e91a5
https://doi.org/10.1101/2021.12.22.473914
https://doi.org/10.1101/2021.12.22.473914
Publikováno v:
Reprod Sci
Preeclampsia is a common obstetrical complication, hallmarked by new-onset hypertension. Believed to result from placental insufficiency and chronic placental ischemia, the symptoms of preeclampsia are caused by release of pathogenic factors from the