Výsledky vyhledávání - "Adrian B Devine"

Akademický článek

The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies.

Autor: Reinhold J Medina, Christina L O'Neill, Adrian B Devine, Tom A Gardiner, Alan W Stitt

Publikováno v: PLoS ONE, Vol 3, Iss 7, p e2584 (2008)

BackgroundCurrent guidelines encourage the use of statins to reduce the risk of cardiovascular disease in diabetic patients; however the impact of these drugs on diabetic retinopathy is not well defined. Moreover, pleiotropic effects of statins on th

Externí odkaz: https://doaj.org/article/a2ff1159eaff41ea86bf0e760e742072

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Expression of the Counter-Regulatory Peptide Intermedin is Augmented in the Presence of Oxidative Stress in Hypertrophied Cardiomyocytes

Autor: Youyou Zhao, Adrian B. Devine, Francis P.G. McCoy, David Bell, Barbara McDermott

Publikováno v: Cellular Physiology and Biochemistry. 21:409-420

Intermedin (IMD), a novel cardiac peptide related to adrenomedullin (AM), protects against myocardial ischemia-reperfusion injury and attenuates ventricular remodelling. IMD's actions are mediated by a calcitonin receptor-like receptor in association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bc01790a92a79f1bca4c2c4e914655
https://doi.org/10.1159/000129633

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Influence of Atenolol and Nifedipine on Nitric-Oxide Deficient Cardiomyocyte Hypertrophy and Expression of the Cardio-Endocrine Peptide Intermedin and its Receptor Components

Autor: David Bell, Barbara McDermott, Youyou Zhao, Adrian B. Devine

Publikováno v: Cellular Physiology and Biochemistry. 21:203-214

Chronic inhibition of nitric oxide (NO) synthesis is associated with hypertension, myocardial ischemia, oxidative stress and hypertrophy; expression of adrenomedullin (AM) and intermedin (IMD) and their receptor activity modifying proteins (RAMPs 1-3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fd84d25bc7dc054c6ade05e15d3cb1
https://doi.org/10.1159/000113870

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Differential effects of an anti-oxidant intervention on cardiomyocyte expression of adrenomedullin and intermedin and their receptor components in chronic nitric oxide deficiency

Autor: Barbara McDermott, David Bell, Francis P.G. McCoy, Youyou Zhao, Adrian B. Devine

Publikováno v: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 20(5)

Background: Chronic inhibition of nitric oxide (NO) synthesis is associated with hypertension, myocardial oxidative stress and hypertrophic remodeling. Up-regulation of the cardiomyocyte adrenomedullin (AM) / intermedin (IMD) receptor signaling casca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ed294d83b2625234efd5d2387294db
https://pubmed.ncbi.nlm.nih.gov/17762156

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Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor system following blood pressure reduction in nitric oxide-deficient hypertension

Autor: Li Zhao, D. Paul Nicholls, Adrian B. Devine, Barbara McDermott, Lisa R. Smith, David Bell, Youyou Zhao, Eugene M. McHenry

Publikováno v: The Journal of pharmacology and experimental therapeutics. 316(3)

Adrenomedullin (AM) and intermedin (IMD; adrenomedulln-2) are vasodilator peptides related to calcitonin gene-related peptide (CGRP). The actions of these peptides are mediated by the calcitonin receptor-like receptor (CLR) in association with one of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594f9bea6487014b456d2555fb132c0e
https://pubmed.ncbi.nlm.nih.gov/16326922

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