Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adrian A, Pater"'
Autor:
Mansi A. Parasrampuria, Adam A. White, Ramadevi Chilamkurthy, Adrian A. Pater, Fatima El-Azzouzi, Katy N. Ovington, Philip J. Jensik, Keith T. Gagnon
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102206- (2024)
Huntington’s disease (HD) is an incurable neurodegenerative disorder caused by genetic expansion of a CAG repeat sequence in one allele of the huntingtin (HTT) gene. Reducing expression of the mutant HTT (mutHTT) protein has remained a clear therap
Externí odkaz:
https://doaj.org/article/17ec7dc92aab4fd2b25cfea55d84c303
Autor:
Michael S. Bosmeny, Adam A. White, Adrian A. Pater, Jennifer Crew, Joshua Geltz, Keith T. Gagnon
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Insufficient tracking of virus introduction, spread, and new lineage emergence for the human monkeypox (mpox) virus 1 (hMPXV1) outbreak of 2022 hindered epidemiological studies and public health response. hMPXV1 mutations accumulated unexpec
Externí odkaz:
https://doaj.org/article/e313a68c883e483797a2c45c88b2b337
Publikováno v:
Human gene therapy. 33(15-16)
Short hairpin RNAs, or short hairpin RNAs (shRNAs), are a proven tool for gene knockdown and a promising therapeutic approach for suppression of disease-associated genes. The efficient preparation of shRNA-expressing vectors can sometimes become a bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a0760cc9af21daff40706442ad4b4c
https://pubmed.ncbi.nlm.nih.gov/35726380
https://pubmed.ncbi.nlm.nih.gov/35726380
Autor:
Sruthi Sudhakar, Christopher L. Barkau, Ramadevi Chilamkurthy, Halle M. Barber, Adrian A. Pater, Sean D. Moran, Masad J. Damha, P.I. Pradeepkumar, Keith T. Gagnon
Publikováno v:
Journal of Biological Chemistry. 299:104700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab30c993bb541c319572c76b107f4a3
https://doi.org/10.1016/j.jbc.2023.104700
https://doi.org/10.1016/j.jbc.2023.104700
Autor:
Mohtashim H. Shamsi, Meera Patwardhan, Ahmad Zaman Qamar, Rana Alkhaldi, Saikat Talapatra, Keith T. Gagnon, Adrian A Pater, Narges Asefifeyzabadi
Publikováno v:
ACS Applied Materials & Interfaces. 12:52156-52165
Flexible and ultrasensitive biosensing platforms capable of detecting a large number of trinucleotide repeats (TNRs) are crucial for future technology development needed to combat a variety of genetic disorders. For example, trinucleotide CGG repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bccc839155641549777022f81603d98
https://doi.org/10.1021/acsami.0c14912
https://doi.org/10.1021/acsami.0c14912
Autor:
Kushal J. Rohilla, Keith T. Gagnon, Adrian A Pater, Maria Barton, Katy N Ovington, Anthony J Henke
Publikováno v:
Hum Genet
Approximately 3% of the human genome is composed of short tandem repeat (STR) DNA sequence known as microsatellites, which can be found in both coding and non-coding regions. When associated with genic regions, expansion of microsatellite repeats bey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948e303aaa2c57f6dcf4f14b00bd039a
https://doi.org/10.1007/s00439-020-02165-z
https://doi.org/10.1007/s00439-020-02165-z
Autor:
Daniel H. Possley, Gregory B. Kharas, Taylor L. Vacala, Adrian A. Pater, Nicholas W. Woo, Nicole M. Jazdzewski, Kaela N. Rivera, Cesar Saucedo, Kelly O. Conger, Edgar J. Crespo, William S. Schjerven, Jonathon D. Knight, Justin E. Spitz, Lissette Arellano, Jordan E. Hollembeak
Publikováno v:
Polymer Bulletin. 77:1433-1448
Novel phenyl-trisubstituted propyl 3-(R-phenyl)-2-cyanoacrylates (where R is 2,4,5-trimethyl, 2,4,6-trimethyl, 2,3-dimethyl-4-methoxy, 2,5-dimethyl-4-methoxy, 2,4-dimethoxy-3-methyl, 2,4-dimethoxy-6-methyl, 4-hydoxy-3,5-dimethyl, 2,3,4-trimethoxy, 2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c63416de782118d7e3c948f6062ffc7
https://doi.org/10.1007/s00289-019-02810-2
https://doi.org/10.1007/s00289-019-02810-2
Autor:
Mansi Parasrampuria, Katy N Ovington, Adam A White, Christopher L. Barkau, Keith T. Gagnon, Adrian A Pater, Rourke J Sylvain, Madison M Hebert, Abadat O Yinusa, Scott W Benzinger, Seth B. Eddington, Michael S Bosmeny, Ramadevi Chilamkurthy, Paige E Metz
In late 2019, a novel coronavirus began spreading in Wuhan, China, causing a potentially lethal respiratory viral infection. By early 2020, the novel coronavirus, called SARS-CoV-2, had spread globally, causing the COVID-19 pandemic. The infection an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f352cea6b11a9071e7ebb58c5b1ec9cc
https://doi.org/10.1101/2021.02.09.430478
https://doi.org/10.1101/2021.02.09.430478
Autor:
Keith T. Gagnon, Adrian A Pater, Madison M Hebert, Katy N Ovington, Abadat O Yinusa, Paige E Metz, Ramdevi Chilamkurthy, Adam A White, Mansi Parasrampuria, Koushik Sinha, Scott W Benzinger, Seth B. Eddington, Michael S Bosmeny, Christopher L. Barkau, Rourke J Sylvain
Genomic virus surveillance can lead to early identification of new variants and inform proper response during a pandemic. Using this approach, we have identified a new variant of the SARS-CoV-2 virus that emerged in the United States (U.S.) early in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725d67298ce12d3a2249f8e259bfa75f
https://doi.org/10.1101/2021.01.11.426287
https://doi.org/10.1101/2021.01.11.426287
Autor:
Narges, Asefifeyzabadi, Rana, Alkhaldi, Ahmad Z, Qamar, Adrian A, Pater, Meera, Patwardhan, Keith T, Gagnon, Saikat, Talapatra, Mohtashim H, Shamsi
Publikováno v:
ACS applied materialsinterfaces. 12(46)
Flexible and ultrasensitive biosensing platforms capable of detecting a large number of trinucleotide repeats (TNRs) are crucial for future technology development needed to combat a variety of genetic disorders. For example, trinucleotide CGG repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbbfeca1e3bc477fd57fe73fc91b7e59
https://pubmed.ncbi.nlm.nih.gov/33151065
https://pubmed.ncbi.nlm.nih.gov/33151065