Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Adrian Newman-Tancredi"'
Autor:
Sarah Chaib, Benjamin Vidal, Caroline Bouillot, Ronan Depoortere, Adrian Newman-Tancredi, Luc Zimmer, Elise Levigoureux
Publikováno v:
NeuroImage: Clinical, Vol 39, Iss , Pp 103497- (2023)
Introduction: The leading treatment for motor signs of Parkinson's disease is L-DOPA, but, upon extended use, it can lead to levodopa-induced dyskinesia (LID). Serotonergic neurons are involved in LID etiology and previous pre-clinical studies have s
Externí odkaz:
https://doaj.org/article/96c2dadb0cb244a6b8ae37d32e96c777
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The serotonin 5-HT1A receptor has attracted wide attention as a target for treatment of psychiatric disorders. Although this receptor is important in the pharmacological mechanisms of action of new-generation antipsychotics, its characteriza
Externí odkaz:
https://doaj.org/article/80f2123f58d84d48a2b3654efb43cad1
Autor:
Kate Beecher, Joshua Wang, Fatemeh Chehrehasa, Ronan Depoortere, Mark A. Varney, Adrian Newman-Tancredi, Selena E. Bartlett, Arnauld Belmer
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112699- (2022)
The rise in obesity prevalence has been linked to overconsumption of high-sugar containing food and beverages. Recent evidence suggests that chronic sucrose consumption leads to changes in serotonergic neuroplasticity within the neural circuits invol
Externí odkaz:
https://doaj.org/article/98e8da94825940cc87384c6c7a72f083
Autor:
Rafael Pazinatto Aguiar, Lígia Mendes Soares, Mark Varney, Adrian Newman-Tancredi A, Humberto Milani, Jos Prickaerts, Rúbia Maria Weffort de Oliveira
Publikováno v:
Neurobiology of Aging, 124, 52-59. Elsevier Science
5-HT1A serotonin receptors may play a role in cognitive function changes related to advanced age. Here, we investigated the effects of acute and repeated treatment with NLX-101 (F15599), a postsynaptic 5-HT1A receptor-biased agonist, and F13714, a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d328c83a30e0436872e2ab14b36749a5
https://cris.maastrichtuniversity.nl/en/publications/b30e5eb0-07ae-4f7d-865b-04f16cab8b24
https://cris.maastrichtuniversity.nl/en/publications/b30e5eb0-07ae-4f7d-865b-04f16cab8b24
Autor:
Joana Pereira-Sousa, Bruna Ferreira-Lomba, Aina Bellver-Sanchis, Daniela Vilasboas-Campos, Jorge H. Fernandes, Marta D. Costa, Mark A. Varney, Adrian Newman-Tancredi, Patrícia Maciel, Andreia Teixeira-Castro
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105278- (2021)
Machado-Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disorder that affects movement coordination leading to a premature death. Despite several efforts, no disease-modifying treatment is yet available
Externí odkaz:
https://doaj.org/article/e41189f9afdf44e5bfd5004837e21f7b
Autor:
Matthieu Colom, Benjamin Vidal, Sylvain Fieux, Jérôme Redoute, Nicolas Costes, Franck Lavenne, Inés Mérida, Zacharie Irace, Thibaud Iecker, Caroline Bouillot, Thierry Billard, Adrian Newman-Tancredi, Luc Zimmer
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
IntroductionSerotonin is involved in a variety of physiological functions and brain disorders. In this context, efforts have been made to investigate the in vivo fluctuations of this neurotransmitter using positron emission tomography (PET) imaging p
Externí odkaz:
https://doaj.org/article/191ab2b523a242d4b75c9265f7132537
Autor:
Sharon Cabanu, Fuencisla Pilar-Cuéllar, Paula Zubakina, Eva Florensa-Zanuy, Júlia Senserrich, Adrian Newman-Tancredi, Albert Adell
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 337 (2022)
Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT1A receptors have attracted interest as tar
Externí odkaz:
https://doaj.org/article/57a3290157564379bb93367a54345fe3
Autor:
Pierre Courault, Sophie Lancelot, Nicolas Costes, Matthieu Colom, Didier Le Bars, Jérôme Redoute, Florent Gobert, Frédéric Dailler, Sibel Isal, Thibaut Iecker, Adrian Newman-Tancredi, Inés Merida, Luc Zimmer
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 50:1651-1664
Purpose F13640 (a.k.a. befiradol, NLX-112) is a highly selective 5-HT1A receptor ligand that was selected as a PET radiopharmaceutical-candidate based on animal studies. Due to its high efficacy agonist properties, [18F]F13640 binds preferentially to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6892e8556aea1904b45a4c7e320637
https://doi.org/10.1007/s00259-022-06103-1
https://doi.org/10.1007/s00259-022-06103-1
Publikováno v:
Molecular Psychiatry. 27:4599-4610
Alcohol-use-disorders are chronic relapsing illnesses, often co-morbid with anxiety. We have previously shown using the “drinking-in-the-dark” model in mice that the stimulation of the serotonin receptor 1A (5-HT1A) reduces ethanol binge-drinking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208c9c2e97b6c324969c45d6390b4415
https://doi.org/10.1038/s41380-022-01789-z
https://doi.org/10.1038/s41380-022-01789-z
Autor:
Monika Głuch-Lutwin, Kinga Sałaciak, Karolina Pytka, Alicja Gawalska, Marek Jamrozik, Joanna Śniecikowska, Marcin Kołaczkowski, Ronan Y. Depoortère, Adrian Newman-Tancredi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2249b023d8daf0bfbb8a81537f862d27
https://ruj.uj.edu.pl/xmlui/handle/item/303825
https://ruj.uj.edu.pl/xmlui/handle/item/303825
