Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Adrian, Sacher"'
Autor:
Ruth Moulson, Jennifer Law, Adrian Sacher, Geoffrey Liu, Frances A. Shepherd, Penelope Bradbury, Lawson Eng, Sandra Iczkovitz, Erica Abbie, Julia Elia-Pacitti, Emmanuel M. Ewara, Viktoriia Mokriak, Jessica Weiss, Christopher Pettengell, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 1947-1960 (2024)
Real-world evidence for patients with advanced EGFR-mutated non-small cell lung cancer (NSCLC) in Canada is limited. This study’s objective was to use previously validated DARWENTM artificial intelligence (AI) to extract data from electronic heath
Externí odkaz:
https://doaj.org/article/fcfae28c3a5541b497cdc9f018c04ea0
Autor:
Parneet K. Cheema, Shantanu O. Banerji, Normand Blais, Quincy S.-C. Chu, Rosalyn A. Juergens, Natasha B. Leighl, Adrian Sacher, Brandon S. Sheffield, Stephanie Snow, Mark Vincent, Paul F. Wheatley-Price, Stephen Yip, Barbara L. Melosky
Publikováno v:
Current Oncology, Vol 30, Iss 7, Pp 6473-6496 (2023)
Activating mutations in Kirsten rat sarcoma viral oncogene homologue (KRAS), in particular, a point mutation leading to a glycine-to-cysteine substitution at codon 12 (G12C), are among the most frequent genomic alterations in non-small cell lung canc
Externí odkaz:
https://doaj.org/article/ab0cb512b2d24cbeafaef622627ed0b6
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Kirsten rat sarcoma viral oncogene homolog mutations are observed in 25% of lung adenocarcinoma and 40% of these are G12C mutations. Historically, no approved targeted agents were available for patients with any KRAS mutation, and response rates to s
Externí odkaz:
https://doaj.org/article/a72cd08431844f868d2e8b1e1cddf4db
Autor:
Lucy Corke, Adrian Sacher
Publikováno v:
Current Oncology, Vol 29, Iss 1, Pp 38-55 (2021)
Immune checkpoint inhibitors have transformed the treatment of metastatic non-small-cell lung cancer, yielding marked improvements in survival and the potential for durable clinical responses. Primary and acquired resistance to current immune checkpo
Externí odkaz:
https://doaj.org/article/7e4d05818e9443c1ae987dd4d41fcc62
Autor:
Miguel Garcia-Pardo, Kasia Czarnecka, Jennifer H. Law, Alexandra Salvarrey, Roxanne Fernandes, Jason Fan, Lucy Corke, Thomas K. Waddell, Kazuhiro Yasufuku, Laura L. Donahoe, Andrew Pierre, Lisa W. Le, Noor Ghumman, Geoffrey Liu, Frances A. Shepherd, Penelope Bradbury, Adrian Sacher, Tracy Stockley, Prodipto Pal, Patrik Rogalla, Ming Sound Tsao, Natasha B. Leighl
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Introduction: Molecular profiling of tumor tissue is the gold standard for treatment decision-making in advanced non-small cell lung cancer (NSCLC). Results may be delayed or unavailable due to insufficient tissue, prolonged wait times for biopsy, pa
Externí odkaz:
https://doaj.org/article/6d16f75f675e4c909e12ca7dabb73091
Autor:
Marie-Pier Gauthier, MD, Jennifer H. Law, MSc, Lisa W. Le, MSc, Janice J.N. Li, BSc, Sajda Zahir, Sharon Nirmalakumar, BSc, Mike Sung, MD, Christopher Pettengell, BMBCh, Steven Aviv, BBusSc, Ryan Chu, MD, Adrian Sacher, MD, MSc, Geoffrey Liu, MD, MSc, Penelope Bradbury, MBChB, Frances A. Shepherd, MD, Natasha B. Leighl, MD, MMSc, FRCPC, FASCO
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100340- (2022)
Introduction: Real-world evidence is important in regulatory and funding decisions. Manual data extraction from electronic health records (EHRs) is time-consuming and challenging to maintain. Automated extraction using natural language processing (NL
Externí odkaz:
https://doaj.org/article/2e86472fb96d485497868949b557bcaa
Autor:
Shirley Xue Jiang, Ryan N. Walton, Katrina Hueniken, Justine Baek, Alexandra McCartney, Catherine Labbé, Elliot Smith, Sze Wah Samuel Chan, RuiQi Chen, Catherine Brown, Devalben Patel, Mindy Liang, Lawson Eng, Adrian Sacher, Penelope Bradbury, Natasha B. Leighl, Frances A. Shepherd, Wei Xu, Geoffrey Liu, Manjusha Hurry, Grainne M. O'Kane
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7542-7555 (2019)
Abstract Background As the treatment landscape in patients with non‐small cell lung cancer (NSCLC) harboring mutations in the epidermal growth factor receptor (EGFRm) continues to evolve, real‐world health utility scores (HUS) become increasingly
Externí odkaz:
https://doaj.org/article/c847915c6e9a44aea2fbbc380f249647
Autor:
Barbara Melosky, Parneet Cheema, Rosalyn A. Juergens, Natasha B. Leighl, Geoffrey Liu, Paul Wheatley-Price, Adrian Sacher, Stephanie Snow, Ming-Sound Tsao, Deanna McLeod, Quincy Chu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Adjuvant platinum-based chemotherapy is standard of care for patients with resected stage IIA/B or IIIA NSCLC. Overall survival is suboptimal due to the high metastatic potential of early-stage NSCLC and there is substantial clinical need
Externí odkaz:
https://doaj.org/article/b7c460474e584b6ca7677d4ff0d6ecf3
Autor:
Jeffrey Weber, Hassane Zarour, David Carbone, Marcus Butler, Roma Patel, Melissa Johnson, Adrian Sacher, Edward Garon, Arindam Dhar, Cristina Messina, Kristin Blouch, Axel Hoos, Anne-Marie Martin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/53ad820e499e4b9d86e1c453a86a2cd6
Autor:
Wade T. Iams, Meridith L. Balbach, Sharon Phillips, Adrian Sacher, Christine Bestvina, Vamsidhar Velcheti, Xiao Wang, Melina E. Marmarelis, Nan Sethakorn, Ticiana Leal, Paul E. Sackstein, Chul Kim, MD Andrew Robinson, Kathan Mehta, Robert Hsu, Jorge Nieva, Tejas Patil, D. Ross Camidge
Publikováno v:
Clinical Lung Cancer. 24:228-234
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f0585933da6b64806798c73252a8d91
https://doi.org/10.1016/j.cllc.2023.01.009
https://doi.org/10.1016/j.cllc.2023.01.009