Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Adrian, Lupescu"'
Autor:
Elisabeth Lang, Christine Zelenak, Matthias Eberhard, Rosi Bissinger, Anand Rotte, Mehrdad Ghashghaeinia, Adrian Lupescu, Florian Lang, Syed M. Qadri
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 3, Pp 1178-1186 (2015)
Background/Aims: The cyclin-dependent kinase 4 (CDK4) participates in the regulation of apoptosis of nucleated cells by altering transcriptional regulation of genes governing cell proliferation and cell death. Similar to apoptosis of nucleated cells,
Externí odkaz:
https://doaj.org/article/7b2c67301b5349a9bf860faa43c6d6b5
Autor:
Elisabeth Lang, Kashif Jilani, Rosi Bissinger, Rexhep Rexhepaj, Christine Zelenak, Adrian Lupescu, Florian Lang, Syed M. Qadri
Publikováno v:
Kidney & Blood Pressure Research, Vol 40, Iss 4, Pp 403-412 (2015)
Background/Aims: Epidemiological evidence suggests that vitamin D deficiency is associated with anemia. The potent metabolite 1,25(OH)2 vitamin D3 [1,25(OH)2D3] activates various signaling cascades regulating a myriad of cellular functions including
Externí odkaz:
https://doaj.org/article/6d211c8b76754b26a9806d15de4f1eea
Autor:
Adrian Lupescu, Rosi Bissinger, Tobias Goebel, Madhuri S. Salker, Kousi Alzoubi, Guilai Liu, Liviu Chirigiu, Andreas F. Mack, Syed M. Qadri, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 2, Pp 773-783 (2015)
Background/Aims: Anemia, a common condition in the elderly, could result from impaired formation and/or from accelerated loss of circulating erythrocytes. The latter could result from premature suicidal erythrocyte death or eryptosis characterized by
Externí odkaz:
https://doaj.org/article/5f95a2a86a6f48a7abb6911b9f067c8c
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 2, Pp 432-442 (2014)
Background/Aims: Cryptotanshinone, a component of Salvia miltiorrhiza Bunge roots, may trigger suicidal death or apoptosis of tumor cells and has thus been recommended for the prevention and treatment of malignancy. On the other hand, Cryptotanshinon
Externí odkaz:
https://doaj.org/article/660802c1841945aea72953e0d8403bbf
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 6, Pp 1838-1848 (2014)
Background/Aims: Gedunin, an inhibitor of heat shock protein HSP90, triggers apoptosis of tumor cells and is thus effective against malignancy. Moreover, the drug has antimalarial potency. In analogy to apoptosis of nucleated cells, erythrocytes may
Externí odkaz:
https://doaj.org/article/5fbf5e1b49b74a51a072a6980bce99d7
Publikováno v:
Toxins, Vol 6, Iss 5, Pp 1559-1574 (2014)
Shikonin, the most important component of Lithospermum erythrorhizon, has previously been shown to exert antioxidant, anti-inflammatory, antithrombotic, antiviral, antimicrobial and anticancer effects. The anticancer effect has been attributed to the
Externí odkaz:
https://doaj.org/article/96f25f412e4440b795c61377dbd58958
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 3, Pp 670-680 (2014)
Background: Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent gene expression and thus compromises cell survival. Similar to survival of nucleated cells, erythrocyte survival could b
Externí odkaz:
https://doaj.org/article/0457d6deec0c40b6bae491feda923593
Publikováno v:
Toxins, Vol 5, Iss 9, Pp 1543-1554 (2013)
The selective cyclooxygenase-2 (COX-2) inhibitor celecoxib triggers apoptosis of tumor cells and is thus effective against malignancy. The substance is at least partially effective through mitochondrial depolarization. Even though lacking mitochondri
Externí odkaz:
https://doaj.org/article/a7f06241d4e240d3b8cfd9c59ce82108
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 2, Pp 291-299 (2013)
Background: Patulin, the most common mycotoxin in apples and apple-derived products, triggers apoptosis and has thus been considered for the treatment of cancer. Similar to apoptosis of nucleated cells, erythrocytes may enter suicidal death or erypto
Externí odkaz:
https://doaj.org/article/c7e513a2a67341a790644de5619f1d6d
Autor:
Gerald Kolb, Maria Cristina Polidori, Ines Gütgemann, Adrian Lupescu, Florian Lang, Gero von Gersdorff, Gabriele Röhrig
Publikováno v:
Zeitschrift für Gerontologie und Geriatrie. 51:343-348