Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Adrian, Jacobo"'
Publikováno v:
eLife, Vol 12 (2024)
In a developing nervous system, axonal arbors often undergo complex rearrangements before neural circuits attain their final innervation topology. In the lateral line sensory system of the zebrafish, developing sensory axons reorganize their terminal
Externí odkaz:
https://doaj.org/article/b6a19fbdcc8949c782c540ce19c169ab
Autor:
Merlin Lange, Alejandro Granados, Shruthi VijayKumar, Jordao Bragantini, Sarah Ancheta, Sreejith Santhosh, Michael Borja, Hirofumi Kobayashi, Erin McGeever, Ahmet Can Solak, Bin Yang, Xiang Zhao, Yang Liu, Angela Detweiler, Sheryl Paul, Honey Mekonen, Tiger Lao, Rachel Banks, Adrian Jacobo, Keir Balla, Kyle Awayan, Samuel D’Souza, Robert Haase, Alexandre Dizeux, Olivier Pourquie, Rafael Gómez-Sjöberg, Greg Huber, Mattia Serra, Norma Neff, Angela Oliveira Pisco, Loïc A. Royer
Elucidating the developmental process of an organism will require the complete cartography of cellular lineages in the spatial, temporal, and molecular domains. We present Zebrahub, a comprehensive dynamic atlas of zebrafish embryonic development tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200f80ba956f87d7f3da8101ab4752cb
https://doi.org/10.1101/2023.03.06.531398
https://doi.org/10.1101/2023.03.06.531398
Publikováno v:
eLife, Vol 7 (2018)
The lateral-line neuromast of the zebrafish displays a restricted, consistent pattern of innervation that facilitates the comparison of microcircuits across individuals, developmental stages, and genotypes. We used serial blockface scanning electron
Externí odkaz:
https://doaj.org/article/687dd16a6f9444d8952176a33baf0a13
Publikováno v:
eLife, Vol 6 (2017)
Dysfunctions of hearing and balance are often irreversible in mammals owing to the inability of cells in the inner ear to proliferate and replace lost sensory receptors. To determine the molecular basis of this deficiency we have investigated the dyn
Externí odkaz:
https://doaj.org/article/514003bf1ab14b4f924f4b095b6ebf9f
Publikováno v:
Nature physics
Actively regulated symmetry breaking, which is ubiquitous in biological cells, underlies phenomena such as directed cellular movement and morphological polarization. Here we investigate how an organ-level polarity pattern emerges through symmetry bre
Autor:
Jennifer Huang, Adrian Jacobo, Nicolas Grillet, Elvis Huarcaya Najarro, Alan G. Cheng, Lee A. Quiruz
Publikováno v:
Development
Planar cell polarity (PCP) proteins localize asymmetrically to instruct cell polarity within the tissue plane, with defects leading to deformities of the limbs, neural tube and inner ear. Wnt proteins are evolutionarily conserved polarity cues, yet W
Autor:
Zvi Fuks, Efsevia Vakiani, Philip B. Paty, Maria Laura Martin, Christy Li, Zhaoshi Zeng, Guoqiang Hua, Adrian Jacobo, Adriana Haimovitz-Friedman, Lixing Zhang, Mohammad Adileh, Richard Kolesnick
Publikováno v:
Cellular Signalling. 42:97-105
Stem cells of the small and large intestine are marked by expression of the Wnt target gene LGR5, a leucine-rich-repeat-containing G protein-coupled receptor. Previous studies reported increased expression of LGR5 in human colorectal cancer (CRC) com
Actively regulated symmetry breaking, which is ubiquitous in biological cells, underlies phenomena such as directed cellular movement and morphological polarization. Here we investigate how an organ-level polarity pattern emerges through symmetry bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf17ac3b6efdcf87597755174a512d3
https://doi.org/10.1101/718502
https://doi.org/10.1101/718502
The development of mechanosensory epithelia, such as those of the auditory and vestibular systems, results in the precise orientation of mechanosensory hair cells and consequently directional sensitivity. After division of a precursor cell in the zeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a909f77952b35b3f9e2dbec263810f80
Publikováno v:
Current Biology. 29:3579-3587.e7
The development of mechanosensory epithelia, such as those of the auditory and vestibular systems, results in the precise orientation of mechanosensory hair cells. After division of a precursor cell in the zebrafish's lateral line, the daughter hair