Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adrian, Elter"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancerous B cells are almost indistinguishable from their non-malignant counterparts regarding their surface antigen expression. Accordingly, the challenge to be faced consists in elimination of the malignant B cell population while maintaining a fun
Externí odkaz:
https://doaj.org/article/660077dd7aed41f2bef39185d7768e7f
Autor:
Adrian Elter, Tina Bock, Dieter Spiehl, Giulio Russo, Steffen C. Hinz, Sebastian Bitsch, Eva Baum, Markus Langhans, Tobias Meckel, Edgar Dörsam, Harald Kolmar, Gerhard Schwall
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Since the pandemic outbreak of Covid-19 in December 2019, several lateral flow assay (LFA) devices were developed to enable the constant monitoring of regional and global infection processes. Additionally, innumerable lateral flow test devic
Externí odkaz:
https://doaj.org/article/46cba929f3f3461aa0a629fdd305a1ef
Autor:
Adrian Elter, Desislava Yanakieva, David Fiebig, Kerstin Hallstein, Stefan Becker, Ulrich Betz, Harald Kolmar
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The interaction of the Fc region of therapeutic antibodies and antibody-drug conjugates with Fcγ receptors (FcγRs) can lead to unpredictable and severe side effects. Over the last decades several strategies have been developed to overcome this draw
Externí odkaz:
https://doaj.org/article/e83dda1bb54546cd838edb4dfd165371
Autor:
Steffen C. Hinz, Adrian Elter, Oliver Rammo, Achim Schwämmle, Ataurehman Ali, Stefan Zielonka, Thomas Herget, Harald Kolmar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Affinity chromatography provides an excellent platform for protein purification, which is a key step in the large scale downstream processing of therapeutic monoclonal antibodies (Mabs). Protein A chromatography constitutes the gold standard for Mab
Externí odkaz:
https://doaj.org/article/d9f77b27f59a460fa48f4fde4750675b
Publikováno v:
Biospektrum
Due to the large evolutionary distance between birds (Aves) und humans, immunization of chickens with human proteins results in a strong response of the bird’s adaptive immune system to proteins of mammalian origin. Additionally, chicken-derived an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee0bdb00b84f1f610453312ccb9fed9
http://europepmc.org/articles/PMC8417631
http://europepmc.org/articles/PMC8417631
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Chicken-derived antibodies emerged as a promising tool for diagnostic and therapeutic usage. Due to the phylogenetic distance between birds and mammals, chicken immunization campaigns with human antigens result in a chicken antibody (IgY) repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::864bc0af1aaa19c0579e782010d20e97
https://pubmed.ncbi.nlm.nih.gov/35482199
https://pubmed.ncbi.nlm.nih.gov/35482199
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e19d0e26cbfc2d101f40e9e228e5a82
https://doi.org/10.1007/978-1-0716-2285-8_18
https://doi.org/10.1007/978-1-0716-2285-8_18
Autor:
Desislava Yanakieva, Adrian Elter, Jens Bratsch, Karlheinz Friedrich, Stefan Becker, Harald Kolmar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
In this study, we present a straightforward approach for functional cell-based screening by co-encapsulation of secretor yeast cells and reporter mammalian cells in millions of individual agarose-containing microdroplets. Our system is compatible wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497d730f2c7ca368524a7dde2cbaca5d
Autor:
Adrian Elter, Tina Bock, Dieter Spiehl, Giulio Russo, Steffen C. Hinz, Sebastian Bitsch, Eva Baum, Markus Langhans, Tobias Meckel, Edgar Dörsam, Harald Kolmar, Gerhard Schwall
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Since the pandemic outbreak of Covid-19 in December 2019, several lateral flow assay (LFA) devices were developed to enable the constant monitoring of regional and global infection processes. Additionally, innumerable lateral flow test devices are fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363c27bc28c47650362c8669d3a0f65d
https://pubmed.ncbi.nlm.nih.gov/33846482
https://pubmed.ncbi.nlm.nih.gov/33846482
Autor:
Adrian Elter, Steffen C. Hinz, David Fiebig, Harald Kolmar, Jan P. Bogen, Björn Hock, Arturo Macarrón Palacios, Julius Grzeschik
Publikováno v:
Biotechnology journal. 16(3)
Generation of high-affinity monoclonal antibodies by immunization of chickens is a valuable strategy, particularly for obtaining antibodies directed against epitopes that are conserved in mammals. A generic procedure is established for the humanizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b676a768785895d3f1e8dd913f2635e
https://pubmed.ncbi.nlm.nih.gov/33078896
https://pubmed.ncbi.nlm.nih.gov/33078896