Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Adriaan B Houtsmuller"'
Autor:
Lieke Koornneef, Johan A Slotman, Esther Sleddens-Linkels, Wiggert A van Cappellen, Marco Barchi, Attila Tóth, Joost Gribnau, Adriaan B Houtsmuller, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010046 (2022)
Recombinases RAD51 and its meiosis-specific paralog DMC1 accumulate on single-stranded DNA (ssDNA) of programmed DNA double strand breaks (DSBs) in meiosis. Here we used three-color dSTORM microscopy, and a mouse model with severe defects in meiotic
Externí odkaz:
https://doaj.org/article/73600dd4da354f6792a689909bee6f67
Autor:
Johan A Slotman, Maarten W Paul, Fabrizia Carofiglio, H Martijn de Gruiter, Tessa Vergroesen, Lieke Koornneef, Wiggert A van Cappellen, Adriaan B Houtsmuller, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008595 (2020)
The recombinase RAD51, and its meiosis-specific paralog DMC1 localize at DNA double-strand break (DSB) sites in meiotic prophase. While both proteins are required during meiotic prophase, their spatial organization during meiotic DSB repair is not fu
Externí odkaz:
https://doaj.org/article/c6b005a3f88a4c6ba0bfe10eaa0dee49
Autor:
Jeffrey Stedehouder, Demi Brizee, Johan A Slotman, Maria Pascual-Garcia, Megan L Leyrer, Bibi LJ Bouwen, Clemens MF Dirven, Zhenyu Gao, David M Berson, Adriaan B Houtsmuller, Steven A Kushner
Publikováno v:
eLife, Vol 8 (2019)
GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood. Here, we report that seg
Externí odkaz:
https://doaj.org/article/4cad7d845a4943d6bf4fae401a2ebf6e
Autor:
Tamara Hoppenbrouwers, Anouchska S A Autar, Andi R Sultan, Tsion E Abraham, Wiggert A van Cappellen, Adriaan B Houtsmuller, Willem J B van Wamel, Heleen M M van Beusekom, Johan W van Neck, Moniek P M de Maat
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176472 (2017)
Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there is much variation in study design and results, our aim was to create a systematic review of NETosis inducers and perform a standard
Externí odkaz:
https://doaj.org/article/2b7d03f564614e1cb8f3d165dff712ab
Quantitation of glucocorticoid receptor DNA-binding dynamics by single-molecule microscopy and FRAP.
Autor:
Femke L Groeneweg, Martin E van Royen, Susanne Fenz, Veer I P Keizer, Bart Geverts, Jurrien Prins, E Ron de Kloet, Adriaan B Houtsmuller, Thomas S Schmidt, Marcel J M Schaaf
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90532 (2014)
Recent advances in live cell imaging have provided a wealth of data on the dynamics of transcription factors. However, a consistent quantitative description of these dynamics, explaining how transcription factors find their target sequences in the va
Externí odkaz:
https://doaj.org/article/d47c3fc061a64d269c690076030ab728
Publikováno v:
Cells, Vol 13, Iss 20, p 1693 (2024)
The androgen receptor (AR), a member of the nuclear steroid hormone receptor family of transcription factors, plays a crucial role not only in the development of the male phenotype but also in the development and growth of prostate cancer. While AR s
Externí odkaz:
https://doaj.org/article/114d2f84ea904314806481cc2398bfd4
Autor:
W Martijn ter Haar, Magda A Meester-Smoor, Karel H M van Wely, Claudia C M M Schot, Marjolein J F W Janssen, Bart Geverts, Jacqueline Bonten, Gerard C Grosveld, Adriaan B Houtsmuller, Ellen C Zwarthoff
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46085 (2012)
The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that ∼20% of GFP-tagged MN1 and T
Externí odkaz:
https://doaj.org/article/d0f348eb9bb8484dbff8f98ebdb66193
Autor:
Karin Legerstee, Jason Sueters, Tsion E. Abraham, Johan A. Slotman, Gert-Jan Kremers, Jacob P. Hoogenboom, Adriaan B. Houtsmuller
Publikováno v:
Biology Open, Vol 11, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/0442c45b12564bca8f692c82b784d27d
Autor:
Isabel Mayayo-Peralta, Sebastian Gregoricchio, Karianne Schuurman, Selçuk Yavuz, Anniek Zaalberg, Aleksandar Kojic, Nina Abbott, Bart Geverts, Suzanne Beerthuijzen, Joseph Siefert, Tesa M Severson, Martijn van Baalen, Liesbeth Hoekman, Cor Lieftink, Maarten Altelaar, Roderick L Beijersbergen, Adriaan B Houtsmuller, Stefan Prekovic, Wilbert Zwart
Publikováno v:
Nucleic Acids Research.
How steroid hormone receptors (SHRs) orchestrate transcriptional activity remains only partly understood. Upon activation, SHRs bind the genome and recruit their co-regulators, crucial to induce gene expression. However, it remains unknown which comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11fe1f74e2cb2daa6028689b386aec3
https://doi.org/10.1093/nar/gkad267
https://doi.org/10.1093/nar/gkad267
Autor:
Christine Helsen, Frank Claessens, Steven Joniau, Adriaan B. Houtsmuller, Lien Spans, Elien Smeets, Thomas Van den Broeck, Kam Y.J. Zhang, Diana Melchers, Rene Houtman, Bart Geverts, Arnout R.D. Voet, Martin E. van Royen, Stefan Prekovic
Table S1: Docking scores for the ligands and the AR mutants. Table S2: FRAP simulation data. Figure S1: Luciferase reporter assay for AR negative prostate cancer cell line (PC3 cells). We used 100 ng of reporter construct; and 10 ng of androgen recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f20dddd2da4f62fbaf9e0b378c4a78b
https://doi.org/10.1158/1535-7163.22508553.v1
https://doi.org/10.1158/1535-7163.22508553.v1
