Effectiveness and safety of integrase strand transfer inhibitors in Spain: a prospective real-world study

Autor: José Ramón Santos, Maria Casadellà, Marc Noguera-Julian, Rafael Micán-Rivera, Pere Domingo, Antonio Antela, Joaquin Portilla, Jesús Sanz, Marta Montero-Alonso, Jordi Navarro, Mar Masiá, Nieves Valcarce-Pardeiro, Antonio Ocampo, Laura Pérez-Martínez, Coral García-Vallecillos, María Jesús Vivancos, Arkaitz Imaz, José Antonio Iribarren, José Hernández-Quero, Judit Villar-García, Pilar Barrufet, Roger Paredes, INSTINCT study group, Mariona Perera, Anna Chamorro, Cristina Miranda, Nástor Sánchez, Anna Garcı́á, Núria Pérez, Juan González Garcı́á, María del Mar Gutiérrez, María Gracia Mateo, Elena Losada, Sergio Reus, Vicente Boix, Diego Torrús, Esperanza Merino, Angela Gutiérrez Liarte, Adrià Curran, Félix Gutiérrez, Anna Mariño Callejo, Alvarez Diaz Hortensia, Antonio Ocampo Hermida, Celia Miralles, Laura Labajo Leal, Guillermo Pousada, José Ramon Blanco, José Antonio Oteo, Ibarra Valvanera, Mercedes Sanz, Luis Metola, Juan Pascua, Daniel Podzamczer, Camila Piatti, Maialen Ibarguren, Laia Arbones, Marta Ruiz, Sara Cervanntes, Helena Pera, Jessica Toro, Nuria Perez-Alvarez, Anna Garcia

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

IntroductionSecond-generation integrase strand transfer inhibitors (INSTIs) are preferred treatment options worldwide, and dolutegravir (DTG) is the treatment of choice in resource-limited settings. Nevertheless, in some resource-limited settings, th

Externí odkaz: https://doaj.org/article/63e60100a5744c33a4e4d6da36790d78

Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab

Autor: Carla Serra-Peinado, Judith Grau-Expósito, Laura Luque-Ballesteros, Antonio Astorga-Gamaza, Jordi Navarro, Jenny Gallego-Rodriguez, Mario Martin, Adrià Curran, Joaquin Burgos, Esteban Ribera, Berta Raventós, Rein Willekens, Ariadna Torrella, Bibiana Planas, Rosa Badía, Felipe Garcia, Josep Castellví, Meritxell Genescà, Vicenç Falcó, Maria J. Buzon

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Here, the authors identify B lymphocyte antigen CD20 as a marker for HIV-infected T cells and provide evidence for the potential use of anti-CD20 antibodies in combination with latency reversing agents for depletion of viral reactivated CD4 T cells i

Externí odkaz: https://doaj.org/article/704040ec0d7d48cf90855591b8bb7358

A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients

Autor: Judith Grau-Expósito, Carla Serra-Peinado, Lucia Miguel, Jordi Navarro, Adrià Curran, Joaquin Burgos, Imma Ocaña, Esteban Ribera, Ariadna Torrella, Bibiana Planas, Rosa Badía, Josep Castellví, Vicenç Falcó, Manuel Crespo, Maria J. Buzon

Publikováno v: mBio, Vol 8, Iss 4 (2017)

ABSTRACT Cells that actively transcribe HIV-1 have been defined as the “active viral reservoir” in HIV-infected individuals. However, important technical limitations have precluded the characterization of this specific viral reservoir during both

Externí odkaz: https://doaj.org/article/1c707eeefab54988a64553436d0814f0

Induction of Resident Memory CD8 T Cell Phenotypes to Eliminate the HIV Reservoir

Autor: Sebastián G. Kuguel, Núria Massana, Cristina Mancebo, Jon Cantero-Pérez, Marina Suppi, Judith Grau-Expósito, Nerea Sánchez-Gaona, Josep Castellví, Laura Mañalich-Barrachina, Cristina Centeno-Mediavilla, Jordi Navarro, Adrià Curran, Vicenç Falcó, Maria J. Buzon, Meritxell Genescà

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a4c35592bc1a9a00eb325234dd22f26
https://doi.org/10.2139/ssrn.4311222

Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study

Autor: Emili Letang, Lorena de la Mora, Sergio Moreno, Montse Laguno, Cristina Cortés, Paula Suanzes, Helem Haydee Vilchez, Esteban Martínez, Jordi Casabona, María Martínez-Rebollar, Francisco Homar, Ingrid Vilaró, Hernando Knobel, María Leyes, Marina Martínez, Alexy Inciarte, Antoni Jou, Jorge Palacio, Pilar Barrufet, Rocio Sola, Elena Leon, Isabel Mur, Felipe García, Angels Jaén, Àngels Masabeu, Elisa de Lazzari, Roser Font, Jose Carlos Rubia, Patrícia Sorní, Bibiana Morell, Ana Silva, José Luis Santiago Blanco, Adrià Curran, Thaïs Comella, Vicenç Falcó, Iván Chivite, Lluís Force, Anna Esteve, Mireia Cairó, Joaquim Peraire, Francesc Vidal, Francisco Fanjul, Berta Torres, Laia Arbones, Maria Saumoy, Josep Vilà, Jordi Aceiton, Guillem Fernandez, Ainoa Ugarte, Joaquín Burgos, David Dalmau, Maria Angels Ribas, Carmen Cifuentes, Josep Mallolas, Lucía Rodríguez, Rosa Maria Vivanco-Hidalgo, Pere Domingo, Eva González, Andreu Bruguera, Elisabet Deig, Consuleo Viladés, Josep M. Llibre, Lorna Leal, Juan Ambrosioni, Montserrat Vargas, Anna Martí, Arkaitz Imaz, Yesika Díaz, Marta Navarro, Aroa Villoslada, Antoni Campins, Freya Gargoulas, Manel Cervantes, Esteve Muntada, Melchor Riera, Sofia Scévola, Javier Murillas, Daniel Podzamczer, Toni Vanrell, Xavier Martinez-Lacas, Jordi Navarro, Antoni Payeras, Sonia Calzado, Maria Gracia Mateo, Elena Chamarro, Leire Berrocal, Ana González-Cordón, Maria Luisa Martin, Juliana Reyes-Urueña, Marta Molero, M. José Amengual, Maribel Tamayo, José M. Miró, Daniel Kwakye Nomah, Amat-Joaquim Orti, Jose Vicente Fernández-Montero, Maria del Mar Gutierrez, Gemma Navarro, Lizza Macorigh, María Peñaranda, Nadia Abdulghani

Publikováno v: The Lancet. HIV
Lancet HIV
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Summary Background Factors affecting outcomes of SARS-CoV-2 infection in people living with HIV are unclear. We assessed the factors associated with SARS-CoV-2 diagnosis and severe outcomes among people living with HIV. Methods We did a retrospective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce7147795ff0e878a9b9ced8644d4cf
https://pubmed.ncbi.nlm.nih.gov/34655548