Zobrazeno 1 - 10
of 476
pro vyhledávání: '"Adoptive cellular therapy"'
Autor:
Ziyun Cheng, Seth-Frerich Fobian, Elena Gurrieri, Mohamadreza Amin, Vito Giuseppe D’Agostino, Mojtaba Falahati, Sara Zalba, Reno Debets, María J. Garrido, Mesha Saeed, Ann L. B. Seynhaeve, Hayri E. Balcioglu, Timo L. M. ten Hagen
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-39 (2024)
Abstract Immunotherapy has become an important part of the oncotherapy arsenal. Its applicability in various cancer types is impressive, as well as its use of endogenous mechanisms to achieve desired ends. However, off-target or on-target-off-tumor t
Externí odkaz:
https://doaj.org/article/9b00f680f44c4519acc61e9173772fa0
Autor:
Meng-Yao Xu, Na Zeng, Chen-Qian Liu, Jian-Xuan Sun, Ye An, Si-Han Zhang, Jin-Zhou Xu, Xing-Yu Zhong, Si-Yang Ma, Hao-Dong He, Jia Hu, Qi-Dong Xia, Shao-Gang Wang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-23 (2024)
Abstract Enhanced cellular therapy has emerged as a novel concept following the basis of cellular therapy. This treatment modality applied drugs or biotechnology to directly enhance or genetically modify cells to enhance the efficacy of adoptive cell
Externí odkaz:
https://doaj.org/article/8ad6007f8ff74808b59c24c681dc65df
Autor:
Joseph A. Mamola, Chun-Yu Chen, Mark A. Currier, Kevin Cassady, Dean A. Lee, Timothy P. Cripe
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 118-124 (2023)
The use of oncolytic viruses (OVs) and adoptive cell therapies (ACT) have independently emerged as promising approaches for cancer immunotherapy. More recently, the combination of such agents to obtain a synergistic anticancer effect has gained atten
Externí odkaz:
https://doaj.org/article/6e5e3ef423954cc8a6709b96845317d9
Autor:
Ahmad Reza Panahi Meymandi, Behnia Akbari, Tahereh Soltantoyeh, Jamshid Hadjati, Daniel J. Klionsky, Behnam Badie, Hamid Reza Mirzaei
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite chimeric antigen receptor (CAR) T cell therapy’s extraordinary success in subsets of B-cell lymphoma and leukemia, various barriers restrict its application in solid tumors. This has prompted investigating new approaches for producing CAR T
Externí odkaz:
https://doaj.org/article/b64d395a31224241a28c776b9b3d16e6
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Due to its widespread occurrence and high mortality rate, hepatocellular carcinoma (HCC) is an abhorrent kind of cancer. Immunotherapy is a hot spot in the field of cancer treatment, represented by immune checkpoint inhibitors (ICIs), which aim to im
Externí odkaz:
https://doaj.org/article/29080b4fc6e040c6aa2c948aac5dcc52
Autor:
Vera S. Donnenberg, James D. Luketich, Ibrahim Sultan, John Lister, David L. Bartlett, Sohini Ghosh, Albert D. Donnenberg
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTreatment options for patients with malignant pleural effusions (MPE) are limited due, at least in part, to the unique environment of the pleural space, which drives an aggressive tumor state and governs the behavior of infiltrating immun
Externí odkaz:
https://doaj.org/article/1c333705aa1c44a4b17a9967cb1ab77b
Autor:
Hanmin Wang, Leo D. Wang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 27- (2023)
Externí odkaz:
https://doaj.org/article/a479b60bf9fc440383c4ec7c3827d1d6
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The ideal strategy to fight an infection involves both (i) weakening the invading pathogen through conventional antimicrobial therapy, and (ii) strengthening defense through the augmentation of host immunity. This is even more pertinent in the contex
Externí odkaz:
https://doaj.org/article/aa2587628c90428b986fe129e8751eea
Publikováno v:
Iranian Journal of Allergy, Asthma and Immunology, Vol 21, Iss 6 (2022)
Cell-based cancer therapies have led to a paradigm shift in the treatment of patients with various cancers. To date, a vast majority of cancer immunotherapies have used genetically engineered T cells to target tumors. Stimulation and ex vivo expansio
Externí odkaz:
https://doaj.org/article/ef8dd183b20a4938bcc17ea8124bdbb1