Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Adoptive/methods"'
1
A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors
Autor: Julie K. Fierle, Johan Abram-Saliba, Vasileios Atsaves, Matteo Brioschi, Mariastella de Tiani, Patrick Reichenbach, Melita Irving, George Coukos, Steven M. Dunn
Publikováno v: Scientific reports, vol. 12, no. 1, pp. 1136
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Anti-tumor therapies that seek to exploit and redirect the cytotoxic killing and effector potential of autologous or syngeneic T cells have shown extraordinary promise and efficacy in certain clinical settings. Such cells, when engineered to express
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0f04a545e225c094ec294c0afd89ac
https://serval.unil.ch/notice/serval:BIB_7D41964E1822
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2
Promising Immuno-Oncology Treatments Beyond the 2018 Nobel Prize
Autor: Ahmad Awada, Luís Castelo-Branco, Ines Pires da Silva, Helena Canhão
Publikováno v: Acta Médica Portuguesa; v. 32, n. 4 (2019): Abril; 251-257
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Acta Médica Portuguesa, Vol 32, Iss 4, Pp 251-257 (2019)
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
Submitted by Ana Quininha (ana.quininha@chlc.min-saude.pt) on 2019-05-16T14:37:51Z No. of bitstreams: 1 AMP 2019 251.pdf: 699585 bytes, checksum: 39db3519e080d1dd5e7a3c10ba2b5b5b (MD5) Made available in DSpace on 2019-05-16T14:37:52Z (GMT). No. of bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f628a90d610a95fa2b14e4d2a39239
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12040
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3
Safety and Tolerability of Adoptive Cell Therapy in Cancer
Autor: Wolf, B., Zimmermann, S., Arber, C., Irving, M., Trueb, L., Coukos, G.
Publikováno v: Drug safety, vol. 42, no. 2, pp. 315-334
Adoptive T cell therapy (ACT) is a safe and effective personalized cancer immunotherapy that can comprise naturally occurring ex vivo expanded cells (e.g., tumor-infiltrating lymphocytes [TIL]) or T cells genetically engineered to confer antigen spec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::4ca7bfc02d71c7b659ca65ef5c64c9a2
https://serval.unil.ch/notice/serval:BIB_944ED4AF4291
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4
Keeping the Engine Running: The Relevance and Predictive Value of Preclinical Models for CAR-T Cell Development
Autor: Migliorini, Denis, Mason, Nicola J, Posey, Avery D
Publikováno v: ILAR journal, Vol. 59, No 3 (2018) pp. 276-285
The cellular immunotherapy field has achieved important milestones in the last 30 years towards the treatment of a variety of cancers due to improvements in ex-vivo T cell manufacturing processes, the invention of synthetic T cell receptors, and adva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::468f2aa191b0ab99154fa66a112c32a7
https://archive-ouverte.unige.ch/unige:150571
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5
The Role of NK Cells in Pig-to-Human Xenotransplantation
Autor: Puga Yung, Gisella, Schneider, Mårten K. J., Seebach, Jörg D.
Publikováno v: Journal of Immunology Research
Journal of Immunology Research, Vol 2017 (2017)
Journal of Immunology Research, Vol. 2017 (2017) P. 4627384
Recruitment of human NK cells to porcine tissues has been demonstrated in pig organs perfused ex vivo with human blood in the early 1990s. Subsequently, the molecular mechanisms leading to adhesion and cytotoxicity in human NK cell-porcine endothelia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9431f5feea4b945bd52f769348b9732d
http://europepmc.org/articles/PMC5749293
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6
Type i CD20 antibodies recruit the B cell receptor for complement-dependent lysis of malignant B cells
Autor: Paul W. H. I. Parren, Marleen Voorhorst, Patrick J. Engelberts, Tom Vink, Frank J. Beurskens, Thomas Valerius, Wendy J.M. Mackus, Joost M. Bakker, Stefanie Derer, Tom van Meerten, Esther C.W. Breij, Janine Schuurman, Jan G. J. van de Winkel
Publikováno v: Engelberts, P J, Voorhorst, M, Schuurman, J, Van Meerten, T, Bakker, J M, Vink, T, Mackus, W J M, Breij, E C W, Derer, S, Valerius, T, van de Winkel, J G J, Parren, P W H I & Beurskens, F J 2016, ' Type i CD20 antibodies recruit the B cell receptor for complement-dependent lysis of malignant B cells ', Journal of Immunology, vol. 197, no. 12, pp. 4829-4837 . https://doi.org/10.4049/jimmunol.1600811
Journal of Immunology, 197(12), 4829-4837. AMER ASSOC IMMUNOLOGISTS
Human IgG1 type I CD20 Abs, such as rituximab and ofatumumab (OFA), efficiently induce complement-dependent cytotoxicity (CDC) of CD20+ B cells by binding of C1 to hexamerized Fc domains. Unexpectedly, we found that type I CD20 Ab F(ab')2 fragments,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d9197ec28f899d5e6a016465f31efa
https://portal.findresearcher.sdu.dk/da/publications/34aca668-9af2-49ed-945c-3a69d108b381
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7
T-cell immunotherapy for malignant glioma: toward a combined approach
Autor: Nhu-Nam Tran Thang, Valérie Dutoit, Pierre-Yves Dietrich, Paul R. Walker
Publikováno v: Current Opinion in Oncology, Vol. 22, No 6 (2010) pp. 604-610
PURPOSE OF REVIEW: Immunotherapies using T lymphocytes are now considered as promising approaches for treating malignant glioma patients. This review discusses how basic understanding of antitumor T-cell responses in the brain are now leading to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a7b464e64bbdf561cd8c35af7e67d6
https://doi.org/10.1097/cco.0b013e32833dead8
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9
The alpha v beta 3 integrin as a tumor homing ligand for lymphocytes
Autor: Daniel F, Legler, Caroline, Johnson-Léger, Guido, Wiedle, Claude, Bron, Beat A, Imhof
Publikováno v: European Journal of Immunology, Vol. 34, No 6 (2004) pp. 1608-1616
Despite the presence of tumor-specific effector cells in the circulation of cancer patients, the immune response of the majority of these patients is not sufficient to prevent the growth and spread of their tumors. That tumor cells can be killed in v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::443a186bd67b22c6a4c93ef4a3c5f346
https://archive-ouverte.unige.ch/unige:11414
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10
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