Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adolph E. Sloboda"'
Autor:
Jay E. Birnbaum, Benjamin M. Sparano, David K. McClintock, Edward L. Tolman, Adolph E. Sloboda
Publikováno v:
Pharmacology. 25:27-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0317f65dd3581b8e20882da6a200fded
https://doi.org/10.1159/000137775
https://doi.org/10.1159/000137775
Autor:
Arnold C. Osterberg, Adolph E. Sloboda
Publikováno v:
Inflammation. 1:415-438
Fenbufen [3-(4-biphenylylcarbonyl)propionic acid] was shown to be an orally and parenterally effective nonsteroidal antiinflammatory analgetic and antipyretic agent in animals. Like clinically useful drugs (aspirin, phenylbutazine and indomethacin) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8e1516192b1902a2cc23135322c290
https://doi.org/10.1007/bf00920340
https://doi.org/10.1007/bf00920340
Autor:
L. A. Harten, D. N. Ridge, John W. Hanifin, B. D. Johnson, G. Nicolau, D. E. Watts, Adolph E. Sloboda, J. Menschik
Publikováno v:
Journal of Medicinal Chemistry. 22:1385-1389
Benzoylacetonitrile and beta-aminocinnamonitrile are shown to possess potent antiinflammatory activity in the rat adjuvant arthritis model. In a series of phenyl-substituted analogues, only o-, m-, and p-fluorobenzoylacetonitrile and m- and p-fluoro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b66e71fa82de427b1c0dee525c23f2
https://doi.org/10.1021/jm00197a020
https://doi.org/10.1021/jm00197a020
Autor:
S. S. Kerwar, Adolph E. Sloboda
Publikováno v:
Agents and Actions. 12:216-220
The effects of fenbufen and sulindac, two novel antiinflammatory agents, on the developing and established lesion of type II collagen arthritis was investigated. Using paw diameter and radiology as parameters, these studies suggest that fenbufen is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a766d7aa8c80629d031c45e126567
https://doi.org/10.1007/bf01965149
https://doi.org/10.1007/bf01965149
Autor:
Adolph E. Sloboda, S. S. Kerwar
Publikováno v:
Pharmacology. 25:12-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb947b01a35aa657c4a13683c92bfae9
https://doi.org/10.1159/000137773
https://doi.org/10.1159/000137773
Publikováno v:
Journal of Pharmaceutical Sciences. 66:466-476
One hundred analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti-inflammatory tests and the 2-phenyl-l,4-benzoquinone writhing and inflamed paw pressure analgesic tests. Only three retained the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb2bc539db01aaa22d4b6de656f51ba
https://doi.org/10.1002/jps.2600660403
https://doi.org/10.1002/jps.2600660403
Autor:
M. J. Kopac, Adolph E. Sloboda
Publikováno v:
Annals of the New York Academy of Sciences. 100:305-333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb09ed86f506b76bdcfc4daae111e715
https://doi.org/10.1111/j.1749-6632.1963.tb57128.x
https://doi.org/10.1111/j.1749-6632.1963.tb57128.x
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229f890263ae893de79af32688e74275
https://doi.org/10.1002/chin.197933169
https://doi.org/10.1002/chin.197933169
Publikováno v:
Agents and actions. 10(1 Pt 2)
Arthritic synovial tissue when cultured with normal articular cartilage induces a breakdown of articular cartilage proteoglycans. No collagen breakdown occurs unless the macroglobulins are inactivated by pretreatment with acid. Proteoglycan breakdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a45cbd5950c74bb5c5f6c61e90a965d
https://pubmed.ncbi.nlm.nih.gov/6992543
https://pubmed.ncbi.nlm.nih.gov/6992543
Autor:
M. J. Landes, John W. Hanifin, D. N. Ridge, B. A. Regan, Arnold C. Osterberg, S.A. Lang, Adolph E. Sloboda, G. J. Patel
Publikováno v:
Journal of pharmaceutical sciences. 69(7)
Several formamidine and acetamidine derivatives prepared from 3-amino-1,2,4-benzotriazine and 3-amino-1,2,4-benzotriazine-1-oxide displayed an aspirin-like anti-inflammatory and analgesic profile. The test systems included adjuvant-induced arthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be9dcd17cd2cd15c095afc12f13284d
https://pubmed.ncbi.nlm.nih.gov/6967113
https://pubmed.ncbi.nlm.nih.gov/6967113