Sustained local delivery of siRNA from an injectable scaffold

Autor: Nelson, Christopher E., Gupta, Mukesh K., Adolph, Elizabeth J., Shannon, Joshua M., Guelcher, Scott A., Duvall, Craig L.

Publikováno v: In Biomaterials February 2012 33(4):1154-1161

Injected Biodegradable Polyurethane Scaffolds Support Tissue Infiltration and Delay Wound Contraction in a Porcine Excisional Model

Autor: Adolph, Elizabeth J., Guo, Ruijing, Pollins, Alonda C., Zienkiewicz, Katarzyna, Cardwell, Nancy, Davidson, Jeffrey M., Guelcher, Scott A., Nanney, Lillian B.

The filling of wound cavities with new tissue is a challenge. We previously reported on the physical properties and wound healing kinetics of prefabricated, gas-blown polyurethane (PUR) scaffolds in rat and porcine excisional wounds. To address the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5fa665b4ea8a945255f8c2756d32047
https://europepmc.org/articles/PMC4837087/

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siRNA Delivery from an Injectable Scaffold for Wound Therapy.

Autor: Nelson CE; Department of Biomedical Engineering, Vanderbilt University , Nashville, Tennessee., Gupta MK; Department of Biomedical Engineering, Vanderbilt University , Nashville, Tennessee., Adolph EJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University , Nashville, Tennessee., Guelcher SA; Department of Biomedical Engineering, Vanderbilt University , Nashville, Tennessee. ; Department of Chemical and Biomolecular Engineering, Vanderbilt University , Nashville, Tennessee., Duvall CL; Department of Biomedical Engineering, Vanderbilt University , Nashville, Tennessee.

Publikováno v: Advances in wound care [Adv Wound Care (New Rochelle)] 2013 Apr; Vol. 2 (3), pp. 93-99.