Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adolfo Quiñones-Lombraña"'
Autor:
Jennifer K. Lang, Badri Karthikeyan, Adolfo Quiñones-Lombraña, Rachael Hageman Blair, Amy P. Early, Ellis G. Levine, Umesh C. Sharma, Javier G. Blanco, Tracey O’Connor
Publikováno v:
Cardio-Oncology, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Background The CBR3 V244M single nucleotide polymorphism has been linked to the risk of anthracycline-related cardiomyopathy in survivors of childhood cancer. There have been limited prospective studies examining the impact of CBR3 V244M on
Externí odkaz:
https://doaj.org/article/89fad400f0164475859f191de1cdfeae
Autor:
Diren Beyoğlu, Eun-Jung Park, Adolfo Quiñones-Lombraña, Asim Dave, Falguni Parande, John M. Pezzuto, Jeffrey R. Idle
Publikováno v:
Food & Function. 13:8489-8499
The benefits of fruit and vegetable dietary consumption are largely defined in epidemiological terms. Relatively little is known about the discrete effects on metabolic pathways elicited by individual dietary fruits and vegetables. To address this, g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65185c1fd048d03edb25b4b9a1084c4c
https://doi.org/10.1039/d2fo00961g
https://doi.org/10.1039/d2fo00961g
Autor:
Adolfo Quiñones-Lombraña, Daniel C. Ferguson, Romina B. Cejas, Jonathan E. Bard, Javier G. Blanco
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
FcRn mediates recycling and transcytosis of IgG and albumin in various cell types. The MHC-class-I-like protein of the FcRn heterodimer is encoded by FCGRT. Few determinants of variable FCGRT expression in humans have been identified so far. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5849aba84413a75dbff679c383941685
http://link.springer.com/article/10.1038/s41598-019-45203-1
http://link.springer.com/article/10.1038/s41598-019-45203-1
Publikováno v:
Toxicol Lett
Aldo-Keto Reductase Family 7 Member A2 (AKR7A2) is the most abundant anthracycline metabolizing enzyme in human myocardium. Myocardial AKR7A2 contributes to the synthesis of cardiotoxic C-13 anthracycline alcohol metabolites (e.g., doxorubicinol). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25ce7811c06b33f8b38b795fb080c0b
https://doi.org/10.1016/j.toxlet.2019.02.015
https://doi.org/10.1016/j.toxlet.2019.02.015
Autor:
G. Ekin Atilla-Gokcumen, Adolfo Quiñones-Lombraña, Virginia del Solar, Nasi Li, Javier G. Blanco
Publikováno v:
Biopharmaceutics & Drug Disposition. 39:315-318
Loxoprofen is an anti-inflammatory drug that requires bioactivation into the trans-OH metabolite to exert pharmacological activity. Evidence suggests that carbonyl reductase 1 (CBR1) is important during the bioactivation of loxoprofen. This study exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6d609335b2519b3417e9f0b4c6e2e65
https://doi.org/10.1002/bdd.2135
https://doi.org/10.1002/bdd.2135
Publikováno v:
Gene. 628:286-294
The ERBB2 gene encodes a transmembrane tyrosine kinase receptor that belongs to the epidermal growth factor receptor (EGFR) family. ERBB2 plays a pivotal role during heart development and is essential for normal cardiac function, particularly during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb54dc94f0f68d47bc4d942c69bc78d
https://doi.org/10.1016/j.gene.2017.07.058
https://doi.org/10.1016/j.gene.2017.07.058
Autor:
Scott H. Stewart, Adolfo Quiñones-Lombraña, Kathleen Shyhalla, Javier G. Blanco, Denise Swiatek, Linda Paine Hughes, Kimberly S. Walitzer
Publikováno v:
J Subst Abuse Treat
Medication-assisted behavior treatment for alcohol use disorder (AUD) holds promise to enhance the efficacy of medication and of behavior therapy when administered individually. The present study examines the treatment benefit of combined outpatient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b2451febc8f6d366e9dec4bbcf25c1
https://europepmc.org/articles/PMC6684329/
https://europepmc.org/articles/PMC6684329/
Autor:
Adolfo, Quiñones-Lombraña, Nasi, Li, Virginia, Del Solar, G Ekin, Atilla-Gokcumen, Javier G, Blanco
Publikováno v:
Biopharmaceuticsdrug disposition. 39(6)
Loxoprofen is an anti-inflammatory drug that requires bioactivation into the trans-OH metabolite to exert pharmacological activity. Evidence suggests that carbonyl reductase 1 (CBR1) is important during the bioactivation of loxoprofen. This study exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53a474f82794346c7903a2e68dd6128d
https://pubmed.ncbi.nlm.nih.gov/29851133
https://pubmed.ncbi.nlm.nih.gov/29851133
Autor:
Tomás Palomo, Miguel Ángel Jiménez-Arriero, Janet Hoenicka, Estrella Rubio-Solsona, Noelia Guerra Martín-Palanco, Adolfo Quiñones-Lombraña, Guillermo Ponce
Publikováno v:
Neurotoxicity Research. 29:345-350
The ankyrin repeat and kinase domain containing 1 (ANKK1) TaqIA polymorphism has been extensively studied as a marker of the gene for dopamine receptor D2 (DRD2) in addictions and other dopamine-associated traits. In vitro mRNA and protein studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee8f6507387706945064901da8798bb
https://doi.org/10.1007/s12640-015-9545-9
https://doi.org/10.1007/s12640-015-9545-9
Publikováno v:
Mitochondrial DNA. 27:896-903
Cancer patients with Down syndrome (DS) are at increased risk for anthracycline-related cardiotoxicity. Mitochondrial DNA (mtDNA) alterations in hearts with-DS may contribute to anthracycline-related cardiotoxicity. Cardiac mtDNA and the mtDNA(4977)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997ebabc95d45c3ff5683aaf3d76996e
https://doi.org/10.3109/19401736.2014.926477
https://doi.org/10.3109/19401736.2014.926477