Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adolfo E Cuadra"'
Autor:
Qing-Hui Chen, Zhiying Shan, Adolfo E. Cuadra, Michael J. Huber, Cassie Cecchettini, Rupsa Basu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H880-H887
Previous studies have indicated that hyperactivity of brain prorenin receptors (PRR) is implicated in neurogenic hypertension. However, the role of brain PRR in regulating arterial blood pressure (ABP) is not well understood. Here, we test the hypoth
Publikováno v:
Journal of Cellular Physiology. 229:333-342
Arginine-vasopressin (AVP) plays a major role in maintaining cardiovascular function and related pathologies. The mechanism involved in its release into the circulation is complex and highly regulated. Recent work has implicated the purinergic recept
Autor:
Nicolas Hussy, Thomas K. Knott, Ryan H. Lee, José R. Lemos, Edward E. Custer, Adolfo E. Cuadra, Sonia Ortiz-Miranda
Publikováno v:
Journal of Neuroendocrinology. 24:681-689
ATP-induced ionic currents were investigated in isolated terminals and somata of the hypothalamic neurohypophysial system (HNS). Both terminals and somata showed inward rectification of the ATP-induced currents and reversal near 0 mV. In terminals, A
Publikováno v:
Journal of Neuroendocrinology. 24:674-680
Bursts of action potentials are crucial for neuropeptide release from the hypothalamic neurohypophysial system (HNS). The biophysical properties of the ion channels involved in the release of these neuropeptides, however, cannot explain the efficacy
Autor:
Sonia Ortiz-Miranda, Taimur Dad, Edward E. Custer, José R. Lemos, Adolfo E. Cuadra, Cristina Velázquez-Marrero, Govindan Dayanithi
Publikováno v:
Cell Calcium. 51:284-292
The hypothalamic-neurohypophysial system (HNS) controls diuresis and parturition through the release of arginine-vasopressin (AVP) and oxytocin (OT). These neuropeptides are chiefly synthesized in hypothalamic magnocellular somata in the supraoptic a
Autor:
Qiuhong Li, Michael J. Katovich, Zhiying Shan, Gwyneth J. Lamont, Peng Shi, Colin Sumners, Adolfo E. Cuadra, Dale M. Seth, Mohan K. Raizada, L. Gabriel Navar, Ying Dong
Publikováno v:
Circulation Research. 107:934-938
Rationale: Despite overwhelming evidence of the importance of brain renin–angiotensin system (RAS), the very existence of intrinsic brain RAS remains controversial. Objective: To investigate the hypothesis that the brain (pro)renin receptor (PRR) i
Autor:
Adolfo E. Cuadra, Nan Jiang, Leah N. Braseth, Shun Lu, Colin Sumners, Mohan K. Raizada, Peng Shi, Hongwei Li
Publikováno v:
Hypertension. 54:845-851
The centrally mediated cardiovascular regulatory actions of angiotensin II in normal and hypertensive rats include angiotensin II type 1 receptor (AT1R)–mediated actions at the paraventricular nucleus (PVN) of the hypothalamus. Because the PVN cons
Publikováno v:
Journal of Receptors and Signal Transduction. 29:63-66
Aim: The identity of muscarinic acetylcholine receptors (mAchR) involved in cholinergic-mediated contraction of the guinea pig gallbladder has been a matter of debate. Different groups have suggested the involvement of M1, M2, M3, or M4 receptor subt
Publikováno v:
Experimental Physiology. 93:701-708
Recent discovery of (pro)renin receptor (PRR) has revolutionized the field of renin–angiotensin system (RAS) physiology and has underscored the critical role of the local and tissue RAS in the development and establishment of cardiac, vascular and
Autor:
Adolfo E. Cuadra, Esam E. El-Fakahany
Publikováno v:
Molecular Brain Research. 134:198-204
The neuronal form of nitric oxide synthase (nNOS) was generally assumed to be constitutively expressed at a constant level. However, it is now becoming recognized that its expression can be modulated by a number of physiological and pathophysiologica