Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adolfo Carlos Barros, de Souza"'
Autor:
Maria Varela Torres Quintanilha, Giovanna de Azevedo Mello Gobbo, Gabriela Beserra Pinheiro, Adolfo Carlos Barros de Souza, Luana Cristina Camargo, Marcia Renata Mortari
Publikováno v:
Toxins, Vol 16, Iss 8, p 342 (2024)
Epilepsy, a neurological disorder characterized by excessive neuronal activity and synchronized electrical discharges, ranks among the most prevalent global neurological conditions. Despite common use, antiepileptic drugs often result in adverse effe
Externí odkaz:
https://doaj.org/article/845e66b5971e4702a878682205a7f3b0
Autor:
Diogo Vieira Tibery, João Antonio Alves Nunes, Daniel Oliveira da Mata, Luis Felipe Santos Menezes, Adolfo Carlos Barros de Souza, Matheus de Freitas Fernandes-Pedrosa, Werner Treptow, Elisabeth Ferroni Schwartz
Publikováno v:
Toxins, Vol 16, Iss 6, p 257 (2024)
Studies on the interaction sites of peptide toxins and ion channels typically involve site-directed mutations in toxins. However, natural mutant toxins exist among them, offering insights into how the evolutionary process has conserved crucial sequen
Externí odkaz:
https://doaj.org/article/97b0add4bb0b4eb8a0f053462e7a7d37
Autor:
Paulo Henrique de Holanda Veloso Júnior, Karina Smidt Simon, Raffael Júnio Araújo de Castro, Luísa Coutinho Coelho, Fabián Andres Hurtado Erazo, Adolfo Carlos Barros de Souza, Rogério Coutinho das Neves, Viviane Furlan Lozano, Elizabeth Ferroni Schwartz, Aldo Henrique Tavares, Márcia Renata Mortari, Ana Paula Junqueira-Kipnis, Ildinete Silva-Pereira, Anamelia Lorenzetti Bocca
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
Antimicrobial peptides (AMPs) are small molecules with microbicidal and immunoregulatory activities. In this study we evaluated the anti-inflammatory and antimicrobial activities of peptides ToAP3 and ToAP4, AMPs from the venom of the Brazilian scorp
Externí odkaz:
https://doaj.org/article/0ffb0ee4301a46d782215b0c99a0c77a
Autor:
Andréia Biolchi Mayer, Henrique de Oliveira Amaral, Danilo Gustavo Rodrigues de Oliveira, Gabriel Avohay Alves Campos, Priscilla Galante Ribeiro, Solange Cristina Rego Fernandes, Adolfo Carlos Barros de Souza, Raffael Júnio Araújo de Castro, Anamélia Lorenzetti Bocca, Márcia Renata Mortari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d32ec9d31597405f135dbe6a2a80bd83
https://doi.org/10.2139/ssrn.4388019
https://doi.org/10.2139/ssrn.4388019
Fraternine, a Novel Wasp Peptide, Protects against Motor Impairments in 6-OHDA Model of Parkinsonism
Autor:
Andréia Mayer Biolchi, Danilo Gustavo Rodrigues de Oliveira, Henrique de Oliveira Amaral, Gabriel Avohay Alves Campos, Jacqueline Coimbra Gonçalves, Adolfo Carlos Barros de Souza, Marcos Robalinho Lima, Luciano Paulino Silva, Márcia Renata Mortari
Publikováno v:
Toxins, Vol 12, Iss 9, p 550 (2020)
Parkinson’s disease (PD) is a progressive neurodegenerative condition that affects the Central Nervous System (CNS). Insect venoms show high molecular variability and selectivity in the CNS of mammals and present potential for the development of ne
Externí odkaz:
https://doaj.org/article/da26c11ebdf942b9a3c74f6d0eed41ba
Autor:
Luis Felipe Santos, Menezes, Mariza Mendanha, Maranhão, Diogo Vieira, Tibery, Adolfo Carlos Barros, de Souza, Daniel Oliveira, da Mata, Leandro Ambrósio, Campos, Amanda Araújo, Souza, Sonia Maria de, Freitas, Elisabeth Ferroni, Schwartz
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1865:184057
Ts17 was purified from the venom of the scorpion Tityus serrulatus, the most dangerous scorpion species in Brazil. The activity on Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81a29612a498065bc7981f46b2b221d
https://doi.org/10.1016/j.bbamem.2022.184057
https://doi.org/10.1016/j.bbamem.2022.184057
Autor:
Adolfo Carlos Barros de Souza, Caroline Barbosa Farias Mourão, Jonathan Martins do Nascimento, Diogo Vieira Tibery, Elisabeth F. Schwartz
Publikováno v:
Peptides. 145
Peptides isolated from spider venoms are of pharmacological interest due to their neurotoxic activity, acting on voltage-dependent ion channels present in different types of human body tissues. Three peptide toxins titled as Ap2, Ap3 and Ap5 were pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70914200533d851cf68056b8732931c7
https://pubmed.ncbi.nlm.nih.gov/34363923
https://pubmed.ncbi.nlm.nih.gov/34363923
Autor:
Luana Cristina Camargo, Leticia Germina Veras, Gabriela Vaz, Adolfo Carlos Barros de Souza, Márcia Renata Mortari
Publikováno v:
Neuropeptides. 93:102233
Approximately 46.8 million people have been diagnosed worldwide with dementia, of which the most common type is Alzheimer's disease (AD). Since the current AD treatment is incipient and limited, it is essential to develop new drugs to prevent AD. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4394791d8f9ffffa39a6429fc05878a3
https://doi.org/10.1016/j.npep.2022.102233
https://doi.org/10.1016/j.npep.2022.102233
Autor:
Maria Varela Torres Quintanilha, Márcia Renata Mortari, Adolfo Carlos Barros de Souza, Fernando Zamudio-Zuñiga, Kamila Soares Lopes, Lourival D. Possani
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 194
Epilepsy is one of the most common neurological diseases in the world. The objective of this research was to investigate a new peptide from the venom of the social wasp Chartergellus communis useful to the study or pharmacotherapy of epilepsy. The wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33af14f9b0f5257c3ac0403e93e5729
https://pubmed.ncbi.nlm.nih.gov/33610635
https://pubmed.ncbi.nlm.nih.gov/33610635
Autor:
Manuel Humberto Mera López, Michelle Cruz Costa, Ana Carolina Martins Magalhães, Elisabeth F. Schwartz, Dágon Manoel Ribeiro, Beatriz Vasconcelos Ibituruna, Luana Cristina Camargo, Lucas Ferreira da Rocha, Gabriel Avohay Alves Campos, Mosar Corrêa Rodrigues, Lourival D. Possani, Luciana Marangni Nolli, Kamila Soares Lopes, Adolfo Carlos Barros de Souza, Alessa Bembom Garcia, Márcia Renata Mortari, Fernando Zamudio-Zuñiga
Publikováno v:
Peptides. 95:84-93
Chatergellus communis is a wasp species endemic to the neotropical region and its venom constituents have never been described. In this study, two peptides from C. communis venom, denominated Communis and Communis-AAAA, were chemically and biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9ed34dfef395d5e629527c8a8da319
https://doi.org/10.1016/j.peptides.2017.07.012
https://doi.org/10.1016/j.peptides.2017.07.012