Survival and adverse events of elderly patients treated with sorafenib for hepatocellular carcinoma

Autor: Anna Soria, Mariona Calvo, Meritxell Casas, Zara Vidales, Sergio Muñoz-Martínez, Victor Sapena, Marc Puigvehi, Lidia Canillas, Raquel Guardeño, Adolfo Gallego, Beatriz Mínguez, Diana Horta, Ariadna Clos, Silvia Montoliu, Mercè Roget, Maria Reig, Mercedes Vergara

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

IntroductionThe first-line treatment for advanced hepatocellular carcinoma (HCC) is atezolizumab plus bevacizumab, but its availability is not universal and elderly patients are underrepresented in clinical trials. There is little evidence of efficac

Externí odkaz: https://doaj.org/article/ee56ec9457554833bfaf62de8c746951

Real-world evidence of the effectiveness of ombitasvir-paritaprevir/r ± dasabuvir ± ribavirin in patients monoinfected with chronic hepatitis C or coinfected with human immunodeficiency virus-1 in Spain.

Autor: José Manuel Sousa, Mercedes Vergara, Federico Pulido, Gloria Sánchez Antolín, Lander Hijona, Fernando Carnicer, Diego Rincón, Javier Salmerón, Beatriz Mateos-Muñoz, Antoni Jou, Benjamín Polo-Lorduy, Ángel Rubín, Ana Escarda, Patricia Aguilar, Teresa Aldámiz-Echevarría, Luisa García-Buey, José A Carrión, Manuel Hernández-Guerra, Sonia Chimeno-Hernández, Nuria Espinosa, Rosa Mª Morillas, Raúl J Andrade, Manuel Delgado, Adolfo Gallego, Marta Magaz, José María Moreno-Planas, Ángel Estébanez, Mikel Rico, Fernando Menéndez, Blanca Sampedro, Luís Morano, Sonia Izquierdo, José Manuel Zozaya, Manuel Rodríguez, Senador Morán-Sánchez, Sara Lorente, Ignacio Martín-Granizo, Miguel Ángel Von-Wichmann, Marcial Delgado, Amanda Manzanares

Publikováno v: PLoS ONE, Vol 14, Iss 11, p e0225061 (2019)

AimWe describe the effectiveness and safety of the interferon-free regimen ombitasvir/paritaprevir/ritonavir plus dasabuvir with or without ribavirin (OBV/PTV/r ± DSV ± RBV) in a nationwide representative sample of the hepatitis C virus (HCV) monoi

Externí odkaz: https://doaj.org/article/7dbb76fef2474e14bc130178fddbd4a1

Clinical outcome and hemodynamic changes following HCV eradication with oral antiviral therapy in patients with clinically significant portal hypertension

Autor: Jose Luis Calleja, Javier Martínez, Xavier Forns, Adolfo Gallego, Edilmar Alvarado-Tapias, Rafael Bañares, Anna Baiges, Elba Llop, Virginia Hernández-Gea, José Ignacio Fortea, Angela Puente, Agustín Albillos, Sergio Rodríguez-Tajes, Càndid Villanueva, Sabela Lens, Luís Ibáñez-Samaniego, Zoe Mariño, Juan Carlos García-Pagán, Jaume Bosch, Xavier Torras

Publikováno v: Journal of Hepatology. 73:1415-1424

Clinically significant portal hypertension (CSPH), defined as a hepatic venous pressure gradient (HVPG) ≥10 mmHg, persists 24 weeks after sustained virological response (SVR) in up to 78% of patients with HCV-related cirrhosis treated with direct-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6335ab15240777cd53477fb6d2dab0e9
https://doi.org/10.1016/j.jhep.2020.05.050

International and multicenter real‐world study of sorafenib‐treated patients with hepatocellular carcinoma under dialysis

Autor: Aline Lopes Chagas, Gabriel Aballay Soteras, Margarita Sala, Adolfo Gallego, Yolanda Sánchez-Torrijos, Marcus-Alexander Wörns, Carlos Huertas, Leonardo Gomes da Fonseca, Carlos Rodríguez de Lope, Margarita Anders, M. Varela, Manuel Hernández-Guerra, Rogerio Alves, Maria Reig, Sonia Pascual, Marco Sanduzzi-Zamparelli, Tania Hernáez, Lorenza Rimassa, Mário Reis Álvares-da-Silva, Alessandro Granito, Juan Arenas, Beatriz Minguez, Cassia Leal, Ana Matilla, Jordi Bruix, Morten Ladekarl, Alberto Lué, Alex Vianey Callado França, Christie Perelló, Rodolfo Sacco, José Luis Lledó, Álvaro Díaz-González, Matthias Pinter, Juan Ignacio Marín, Gustavo Pereira, Susanna Coll, Giovan Giuseppe Di Costanzo, Massimo Iavarone, Ángela Rojas, Federico Piñero, Mercedes Vergara, Edoardo G. Giannini, Jean-Charles Nault, Mar Lozano, Bruno Sangro, Ignacio Garcia Juarez, Vivianne Mello, Josemaría Menéndez, Manuel Delgado

Publikováno v: Díaz-González, Á, Sanduzzi-Zamparelli, M, da Fonseca, L G, Di Costanzo, G G, Alves, R, Iavarone, M, Leal, C, Sacco, R, Matilla, A M, Hernández-Guerra, M, Aballay Soteras, G, Wörns, M A, Pinter, M, Varela, M, Ladekarl, M, Chagas, A L, Mínguez, B, Arenas, J I, Granito, A, Sánchez-Torrijos, Y, Rojas, Á, Rodríguez de Lope, C, Alvares-da-Silva, M R, Pascual, S, Rimassa, L, Lledó, J L, Huertas, C, Sangro, B, Giannini, E G, Delgado, M, Vergara, M, Perelló, C, Lue, A, Sala, M, Gallego, A, Coll, S, Hernáez, T, Piñero, F, Pereira, G, França, A, Marín, J, Anders, M, Mello, V, Lozano, M, Nault, J C, Menéndez, J, García Juárez, I, Bruix, J & Reig, M 2020, ' International and multicenter real-world study of sorafenib-treated patients with hepatocellular carcinoma under dialysis ', Liver International, vol. 40, no. 6, pp. 1467-1476 . https://doi.org/10.1111/liv.14436
LIVER INTERNATIONAL
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Díaz-González, Á, Sanduzzi-Zamparelli, M, Gomes da Fonseca, L L, Di Costanzo, G G, Alves, R, Iavarone, M, Leal, C, Sacco, R, Matilla, A M, Hernández-Guerra, M, Aballay Soteras, G, Wörns, M-A, Pinter, M, Varela, M, Ladekarl, M, Chagas, A L, Mínguez, B, Arenas, J I, Granito, A, Sánchez-Torrijos, Y, Rojas, Á, Rodríguez de Lope, C, Alvares-da-Silva, M R, Pascual, S, Rimassa, L, Lledó, J L, Huertas, C, Sangro, B, Giannini, E G, Delgado, M, Vergara, M, Perelló, C, Lue, A, Sala, M, Gallego, A, Coll, S, Hernáez, T, Piñero, F, Pereira, G, França, A, Marín, J, Anders, M, Mello, V, Lozano, M, Nault, J C, Menéndez, J, García Juárez, I, Bruix, J & Reig, M 2020, ' International and multicenter real-world study of sorafenib-treated patients with hepatocellular carcinoma under dialysis ', Liver International, vol. 40, no. 6, pp. 1467-1476 . https://doi.org/10.1111/liv.14436
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Liver International
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

Background & Aims: Information on safety and efficacy of systemic treatment in patients with hepatocellular carcinoma (HCC) under dialysis are limited due to patient exclusion from clinical trials. Thus, we aimed to evaluate the rate, prevalence, tol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992fc127c396b1c6ac4e38a74d7fb370
https://doi.org/10.1111/liv.14436

Obeticholic Acid and Fibrates in Primary Biliary Cholangitis: Comparative Effects in a Multicentric Observational Study

Autor: Diana Horta, Mercedes Vergara, Jesús M. González-Santiago, Ana Arencibia, Raúl J. Andrade, Carmen Álvarez-Navascués, Pamela Estévez, Elena Gómez-Domínguez, Carlos Ferre-Aracil, Margarita Sala, Marina Berenguer, Rosa Maria Morillas, Esther Molina, Manuel Hernández-Guerra, Emilio Fábrega, Eva Fernández-Bonilla, Judith Gómez-Camarero, Anna Reig, Albert Parés, Moisés Diago, Victor Vargas, Lander Hijona, Adolfo Gallego-Moya, Nadia Chahri, Francisco Suárez, Agustín Albillos, Conrado M. Fernández-Rodríguez, Indhira M Pérez-Medrano, Manuel Romero-Gómez, Marta Casado, Gema De la Cruz

Publikováno v: AMERICAN JOURNAL OF GASTROENTEROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
American Journal of Gastroenterology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia

INTRODUCTION: Obeticholic acid (OCA) and fibrates therapy results in biochemical improvement in placebo-controlled trials in patients with primary biliary cholangitis and insufficient response to ursodeoxycholic acid. There is scarce information outs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e088662551ac70360a47a1fe6ead52fe
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=5308