Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Adnan Azim"'
Autor:
Ali Versi, Adnan Azim, Fransiskus Xaverius Ivan, Mahmoud I Abdel‐Aziz, Stewart Bates, John Riley, Mohib Uddin, Nazanin Zounemat Kermani, Anke‐H Maitland‐Van Der Zee, Sven‐Eric Dahlen, Ratko Djukanovic, Sanjay H Chotirmall, Peter Howarth, Ian M Adcock, Kian Fan Chung, the U‐BIOPRED study group
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Severe asthma (SA) encompasses several clinical phenotypes with a heterogeneous airway microbiome. We determined the phenotypes associated with a low α‐diversity microbiome. Methods Metagenomic sequencing was performed on sputu
Externí odkaz:
https://doaj.org/article/06c9519010764d73bb039e9096a28326
Autor:
Tim JM Wallis, Benjamin Welham, Alex Kong, Tommaso Morelli, Adnan Azim, Jose Horno, Miranda Wilkinson, Hannah Burke, Anna Freeman, Thomas MA Wilkinson, Mark G Jones, Benjamin G Marshall
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Background Routine follow-up of patients hospitalised with COVID-19 is recommended, however due to the ongoing high number of infections this is not without significant health resource and economic burden. In a previous study we investigated
Externí odkaz:
https://doaj.org/article/ae7e9c66437e41fbac34f395445ddbd4
Autor:
Anna T. Freeman, David Hill, Colin Newell, Helen Moyses, Adnan Azim, Deborah Knight, Laura Presland, Matthew Harvey, Hans Michael Haitchi, Alastair Watson, Karl J. Staples, Ramesh J. Kurukulaaratchy, Tom M. A. Wilkinson
Publikováno v:
Asthma Research and Practice, Vol 6, Iss 1, Pp 1-11 (2020)
Abstract Background Exercise is recommended in guidelines for asthma management and has beneficial effects on symptom control, inflammation and lung function in patients with sub-optimally controlled asthma. Despite this, physical activity levels in
Externí odkaz:
https://doaj.org/article/e3f249f3857647de998b59a98b75270c
Autor:
Adnan Azim, Heena Mistry, Anna Freeman, Clair Barber, Colin Newell, Kerry Gove, Yvette Thirlwall, Matt Harvey, Kimberley Bentley, Deborah Knight, Karen Long, Frances Mitchell, Yueqing Cheng, Judit Varkonyi-Sepp, Wolfgang Grabau, Paddy Dennison, Hans Michael Haitchi, S. Hasan Arshad, Ratko Djukanovic, Tom Wilkinson, Peter Howarth, Ramesh J. Kurukulaaratchy
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Asthma is now widely recognised to be a heterogeneous disease. The last two decades have seen the identification of a number of biological targets and development of various novel therapies. Despite this, asthma still represents a
Externí odkaz:
https://doaj.org/article/6f0e734243314ef0a96b91c6660ed495
Autor:
Owen G O'Daly, Daniel Joyce, Derek K Tracy, Adnan Azim, Klaas E Stephan, Robin M Murray, Sukhwinder S Shergill
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218478 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0093955.].
Externí odkaz:
https://doaj.org/article/46f286cf0c7f4e65b2b80754d8628afb
Autor:
Owen G O'Daly, Daniel Joyce, Derek K Tracy, Adnan Azim, Klaas E Stephan, Robin M Murray, Sukhwinder S Shergill
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93955 (2014)
Dysregulation of mesolimbic dopamine transmission is implicated in a number of psychiatric illnesses characterised by disruption of reward processing and goal-directed behaviour, including schizophrenia, drug addiction and impulse control disorders a
Externí odkaz:
https://doaj.org/article/53f2f50b6ce846f7bd83ddc0667e7a18
Autor:
Hitasha Rupani, Mohammed Aref Kyyaly, Adnan Azim, Rana Abadalkareen, Anna Freeman, Paddy Dennison, Peter Howarth, Ratko Djukanovic, Pandurangan Vijayanand, Gregory Seumois, S Hasan Arshad, Hans Michael Haitchi, Ramesh J. Kurukulaaratchy
Background: asthma is conventionally stratified as type 2-inflammation (T2) high or T2-low disease. Identifying T2-status has therapeutic implications for patient management but real-world understanding of this T2 paradigm in difficult-to-treat/ seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0235460390491a0e05a568e1a9a71cbe
https://eprints.soton.ac.uk/477586/
https://eprints.soton.ac.uk/477586/
Autor:
Adnan Azim, Faisal I. Rezwan, Clair Barber, Matthew Harvey, Ramesh J. Kurukulaaratchy, John W. Holloway, Peter H. Howarth
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 10; Pages: 1635
The measurement of exhaled volatile organic compounds (VOCs) in exhaled breath (breathomics) represents an exciting biomarker matrix for airways disease, with early research indicating a sensitivity to airway inflammation. One of the key aspects to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abad4e6a12d18ae3a8fdfa0005d6f15
https://eprints.soton.ac.uk/472170/
https://eprints.soton.ac.uk/472170/
Autor:
Peter H. Howarth, Adnan Azim, Nivenka Jayasekera, Ben Green, Hitasha Rupani, Kenneth D. Bruce, Laurie Lau
Publikováno v:
Allergy. 76:2070-2078
Background: IL-13 is considered an archetypal T2 cytokine central to the clinical disease expression of asthma. The IL-13 response genes, which are upregulated in central airway bronchial epithelial of asthma patients, can be normalized by high-dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34eedb39768aab35bf17b3a5692d04ac
https://doi.org/10.1111/all.14732
https://doi.org/10.1111/all.14732
Autor:
Wei Chern Gavin Fong, Adnan Azim, Deborah Knight, Heena Mistry, Anna Freeman, Mae Felongco, Aref Kyyaly, Matthew Harvey, Patrick Dennison, Hongmei Zhang, Peter Howarth, S Arshad, Ramesh Kurukulaaratchy
Introduction Real-world data on Omalizumab (OMA) and Mepolizumab (MEPO) can inform their use in severe asthma (SA). We studied patients in the Wessex AsThma CoHort of difficult asthma (WATCH) to: 1. Phenotypically compare OMA or MEPO treated patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe2a7381ecfab555778946d6d842c3b
https://doi.org/10.22541/au.164864374.43279903/v1
https://doi.org/10.22541/au.164864374.43279903/v1