Topical Versus Intravenous Tranexamic Acid in Patients Undergoing Cardiac Surgery: The DEPOSITION Randomized Controlled Trial.

Autor: Lamy A; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Surgery (A.L., R.P.W.), McMaster University, Hamilton, ON, Canada., Sirota DA; E. Meshalkin National Medical Research Center, Novosibirsk, Russia (D.A.S.)., Jacques F; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Canada (F.J.)., Poostizadeh A; Kelowna General Hospital, BC, Canada (A.P.)., Noiseux N; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), QC, Canada (N.N.)., Efremov S; Saint Petersburg State University Hospital, Russia (S.E.)., Demers P; Montreal Heart Institute, University of Montréal, QC, Canada (P.D.)., Akselrod B; Petrovsky National Centre of Surgery, Moscow, Russia (B.A.)., Wang CY; Department of Anesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia (C.Y.W.)., Arora RC; Division of Cardiac Surgery, University Hospitals Harrington Heart and Vascular Institute, Cleveland, OH (R.C.A.).; Department of Surgery, Case Western Reserve University, Cleveland, OH (R.C.A.)., Branny P; Department of Cardiac Surgery, Hospital Agel Trinec-Podlesi, Trinec, Czech Republic (P.B.)., McGuinness SP; Auckland City Hospital, New Zealand (S.P.M.)., Brown CD; New Brunswick Heart Centre, Saint John, Canada (C.D.B.)., Jeanmart H; Centre Intégré Universitaire de Santé et de Services Sociaux du Nord-de-l'Île-de-Montréal, Hôpital du Sacré-Coeur de Montréal, QC, Canada (H.J.)., Zhao Q; Rujin Hospital, Shanghai, China (Q.Z.).; Shanghai Jiao Tong University School of Medicine, China (Q.Z.)., Zhang H; Beijing Anzhen Hospital, China (H.Z.)., Belley-Côté EP; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Medicine (E.P.B-C., A.E.F-B., S.Y., P.J.D.), McMaster University, Hamilton, ON, Canada., Whitlock RP; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Surgery (A.L., R.P.W.), McMaster University, Hamilton, ON, Canada., Browne A; Hamilton Health Sciences, Hamilton General Hospital, Ontario, Canada (A.B.)., Copland I; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.)., Vincent J; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.)., Khatun R; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.)., Balasubramanian K; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.)., Bangdiwala SI; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Departments of Health Research Methods, Evidence, and Impact (S.I.B., J.S., P.J.D.), McMaster University, Hamilton, ON, Canada., McGillion MH; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; School of Nursing (M.H.M.), McMaster University, Hamilton, ON, Canada., Fox-Robichaud AE; Medicine (E.P.B-C., A.E.F-B., S.Y., P.J.D.), McMaster University, Hamilton, ON, Canada.; Thrombosis and Atherosclerosis Research Institute (A.E.F-B.), McMaster University, Hamilton, ON, Canada., Spence J; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Departments of Health Research Methods, Evidence, and Impact (S.I.B., J.S., P.J.D.), McMaster University, Hamilton, ON, Canada.; Anesthesia (J.S.), McMaster University, Hamilton, ON, Canada., Yusuf S; Population Health Research Institute, Hamilton, ON, Canada (A.L., E.P.B-C., R.P.W., I.C., J.V., R.K., K.B., S.I.B., M.H.M., J.S., S.Y., P.J.D.).; Medicine (E.P.B-C., A.E.F-B., S.Y., P.J.D.), McMaster University, Hamilton, ON, Canada., Devereaux PJ

Publikováno v: Circulation [Circulation] 2024 Oct 22; Vol. 150 (17), pp. 1315-1323. Date of Electronic Publication: 2024 Apr 08.

Prolonged outpatient parenteral antimicrobial treatment: frequency and evolution over a six-year period in a Swiss University Hospital.

Autor: A M; Infectious Diseases Service, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland. aline.munting@chuv.ch., J D; Infectious Diseases Service, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland., L A; Infectious Diseases Service, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland., M C; Infectious Diseases Service, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland., S V; Infectious Diseases Service, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Publikováno v: BMC infectious diseases [BMC Infect Dis] 2024 Nov 07; Vol. 24 (1), pp. 1255. Date of Electronic Publication: 2024 Nov 07.

Pharmacokinetic and preclinical safety studies of endolysin-based therapeutic for intravenous administration.

Autor: Antonova NP; Laboratory of Pathogen Population Variability Mechanisms, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia., Vasina DV; Laboratory of Pathogen Population Variability Mechanisms, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia., Grigoriev IV; Translational Biomedicine Laboratory, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia., Laishevtsev AI; Federal State Budget Scientific Institution 'Federal Scientific Centre VIEV' (FSC VIEV), Moscow, Russia., Kapustin AV; Federal State Budget Scientific Institution 'Federal Scientific Centre VIEV' (FSC VIEV), Moscow, Russia., Savinov VA; Federal State Budget Scientific Institution 'Federal Scientific Centre VIEV' (FSC VIEV), Moscow, Russia., Vorobev AM; Laboratory of Clinical Microbiology and Biotechnology of Bacteriophages, G.N. Gabrichevsky Moscow Research Institute for Epidemiology and Microbiology, Moscow, Russia., Aleshkin AV; Laboratory of Clinical Microbiology and Biotechnology of Bacteriophages, G.N. Gabrichevsky Moscow Research Institute for Epidemiology and Microbiology, Moscow, Russia., Zackharova AA; Translational Biomedicine Laboratory, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia., Remizov TA; Translational Biomedicine Laboratory, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia., Makarov VV; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Yudin SM; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Gushchin VA; Laboratory of Pathogen Population Variability Mechanisms, N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia. Electronic address: wowaniada@yandex.ru.

Publikováno v: International journal of antimicrobial agents [Int J Antimicrob Agents] 2024 Nov; Vol. 64 (5), pp. 107328. Date of Electronic Publication: 2024 Sep 05.

Effectiveness of switching to subcutaneous infliximab in inflammatory bowel disease patients with inadequate biochemical response during intravenous administration.

Autor: Lee B; Department of Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea., Kim M; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea., Kim ER; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea., Hong SN; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea., Chang DK; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea., Kim YH; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. bowelkim@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2024 Oct 17; Vol. 14 (1), pp. 24347. Date of Electronic Publication: 2024 Oct 17.

Postoperative recovery in peroral versus intravenous antibiotic treatment following laparoscopic appendectomy for complicated appendicitis: a substudy of a cluster randomized cluster crossover non-inferiority study.

Autor: Mohamud AA; Department of Surgery, Slagelse Hospital, Fælledvej 11, DK-4200, Slagelse, Denmark. ahmm@regionsjaelland.dk.; Center for Surgical Science, Zealand University Hospital, 4600, Koege, Denmark. ahmm@regionsjaelland.dk., Zeyghami W; Department of Orthopedic Surgery, Copenhagen University Hospital Hvidovre, 2650, Hvidovre, Denmark., Kleif J; Department of Surgery, Northzealand Hospital, 3400, Hilleroed, Denmark., Gögenur I; Center for Surgical Science, Zealand University Hospital, 4600, Koege, Denmark.

Publikováno v: Langenbeck's archives of surgery [Langenbecks Arch Surg] 2024 Oct 09; Vol. 409 (1), pp. 303. Date of Electronic Publication: 2024 Oct 09.