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479 A new era in skin developmental research: Introducing an iPSC-derived skin organoid co-culture model

Autor: Foster, A., Admane, C., Adao, D., Torabi, F., Gopee, N., Winheim, E., Verger, L., Lee, J., Koehler, K., Haniffa, M.

Publikováno v: Journal of Investigative Dermatology; December 2024, Vol. 144 Issue: 12, Number 12 Supplement 1 pS311-S311, 1p

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Cutaneous T cell lymphoma atlas reveals malignant T H 2 cells supported by a B cell-rich tumor microenvironment.

Autor: Li R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. rli11@mdanderson.org.; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. rli11@mdanderson.org.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA. rli11@mdanderson.org., Strobl J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Poyner EFM; Biosciences Institute, Newcastle University, Newcastle, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Balbaa A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Torabi F; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Mazin PV; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Chipampe NJ; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Stephenson E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Ramírez-Suástegi C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Shanmugiah VBM; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gardner L; Biosciences Institute, Newcastle University, Newcastle, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Olabi B; Biosciences Institute, Newcastle University, Newcastle, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Coulthard R; NovoPath, Department of Cellular Pathology, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Botting RA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Zila N; Department of Dermatology, Medical University of Vienna, Vienna, Austria.; Section Biomedical Science, University of Applied Sciences FH Campus Wien, Vienna, Austria., Prigmore E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gopee NH; Biosciences Institute, Newcastle University, Newcastle, UK.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Chroscik MA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Kritikaki E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Engelbert J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Goh I; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Chan HM; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Johnson HF; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Ellis J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Rowe V; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Tun W; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Reynolds G; Biosciences Institute, Newcastle University, Newcastle, UK.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA., Yang D; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA., Foster AR; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Gambardella L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Winheim E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Admane C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Rumney B; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Steele L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Jardine L; Biosciences Institute, Newcastle University, Newcastle, UK., Nenonen J; Division of Rheumatology, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Pickard K; Biosciences Institute, Newcastle University, Newcastle, UK., Lumley J; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Hampton P; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Hu S; Biomedical Pioneering Innovation Center and School of Life Sciences, Peking University, Beijing, China., Liu F; Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China., Liu X; Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China., Horsfall D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Basurto-Lozada D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Biosciences Institute, Newcastle University, Newcastle, UK., Grimble L; Biosciences Institute, Newcastle University, Newcastle, UK., Bacon CM; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Department of Cellular Pathology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Weatherhead SC; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Brauner H; Division of Rheumatology, Department of Medicine, Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Dermatology, Karolinska University Hospital, Stockholm, Sweden., Wang Y; Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China., Bai F; Biomedical Pioneering Innovation Center and School of Life Sciences, Peking University, Beijing, China., Reynolds NJ; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Allen JE; Lydia Becker Institute of Immunology and Inflammation, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK., Jonak C; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Brunner PM; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. st9@sanger.ac.uk.; Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK. st9@sanger.ac.uk.; Department of Medicine, University of Cambridge, Cambridge, UK. st9@sanger.ac.uk., Haniffa M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. mh32@sanger.ac.uk.; Biosciences Institute, Newcastle University, Newcastle, UK. mh32@sanger.ac.uk.; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle, Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. mh32@sanger.ac.uk.

Publikováno v: Nature immunology [Nat Immunol] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.