A hybrid endovascular and open approach to rare thyrocervical trunk and subclavian pseudoaneurysms complicated by embolic brachial artery occlusion

Autor: Katerina Jou, BS, Lily S.F. Adler, BA, Krystina N. Choinski, MD, Bryan P. Myers, MD, William P. Zickler, MD, Rami O. Tadros, MD, FACS, FSVS, RPVI

Publikováno v: Journal of Vascular Surgery Cases and Innovative Techniques, Vol 10, Iss 4, Pp 101523- (2024)

Subclavian and thyrocervical trunk pseudoaneurysms are rare pathologies and even more so when they occur simultaneously. Treatment of these vascular injuries can be done endovascularly or with open surgery. We present a novel two-stage, hybrid open a

Externí odkaz: https://doaj.org/article/d793ea6f87c24ed59963cb21a4e981a4

A transcriptionally active lipid vesicle encloses the injected Chimalliviridae genome in early infection.

Autor: Armbruster EG; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; These authors contributed equally: Emily G. Armbruster and Phoolwanti Rani., Rani P; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA.; These authors contributed equally: Emily G. Armbruster and Phoolwanti Rani., Lee J; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Klusch N; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA., Hutchings J; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA., Hoffman LY; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA., Buschkaemper H; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität, Munich, Germany., Enustun E; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Adler BA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Inlow K; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., VanderWal AR; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA., Hoffman MY; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Daksh D; National Institute of Science, Education and Research (NISER) Bhubaneshwar, Orissa 752050, India., Aindow A; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Deep A; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA., Rodriguez ZK; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Morgan CJ; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Ghassemian M; Biomolecular and Proteomics Mass Spectrometry Facility, University of California San Diego, La Jolla, CA 92093, USA., Laughlin TG; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Charles E; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Cress BF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Savage DF; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Doudna JA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA.; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; MBIB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Pogliano K; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA., Corbett KD; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA., Villa E; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA., Pogliano J; School of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.

Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases.

Autor: Yoon PH; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA., Zhang Z; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA., Loi KJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Adler BA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA., Lahiri A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Vohra K; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA., Shi H; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA., Rabelo DB; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA., Trinidad M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA., Boger RS; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, USA., Al-Shimary MJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Gladstone Institutes, San Francisco, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Aug 02; Vol. 385 (6708), pp. 538-543. Date of Electronic Publication: 2024 Jul 18.

An essential and highly selective protein import pathway encoded by nucleus-forming phage.

Autor: Morgan CJ; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Enustun E; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Armbruster EG; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Birkholz EA; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Prichard A; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Forman T; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Aindow A; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Wannasrichan W; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093.; Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand 10330., Peters S; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Inlow K; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Shepherd IL; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Razavilar A; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Chaikeeratisak V; Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand 10330., Adler BA; California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720.; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Cress BF; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Doudna JA; California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720.; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; Department of Chemistry, University of California, Berkeley, CA 94720.; HHMI, University of California, Berkeley, CA 94720.; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720., Pogliano K; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093., Villa E; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093.; HHMI, University of California San Diego, La Jolla, CA 92093., Corbett KD; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093., Pogliano J; School of Biological Sciences, Division of Molecular Biology, University of California San Diego, La Jolla, CA 92093.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 07; Vol. 121 (19), pp. e2321190121. Date of Electronic Publication: 2024 Apr 30.

CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.

Autor: Adler BA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Trinidad MI; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Bellieny-Rabelo D; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Zhang E; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Karp HM; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Skopintsev P; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Thornton BW; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Weissman RF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Yoon PH; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Chen L; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA., Hessler T; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA.; Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA 94720, USA.; EGSB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Eggers AR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Colognori D; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Boger R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Doherty EE; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Tsuchida CA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA., Tran RV; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Hofman L; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Graduate School of Life Sciences, Utrecht University, 3584 CS Utrecht, UT, The Netherlands., Shi H; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Wasko KM; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Zhou Z; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Xia C; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Al-Shimary MJ; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Patel JR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Thomas VCJX; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Pattali R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Kan MJ; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Pediatrics, Division of Allergy, Immunology, and Bone Marrow Transplantation, University of California, San Francisco, CA 94158, USA., Vardapetyan A; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Yang A; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Lahiri A; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Maxwell MF; Department of Chemistry and Biochemistry, Hampton University, Hampton, VA 23668, USA., Murdock AG; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Ramit GC; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Henderson HR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Calvert RW; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Bamert RS; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Knott GJ; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Lapinaite A; School of Molecular Sciences, Arizona State University, Tempe, AZ 85281, USA.; Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.; Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA., Pausch P; LSC-EMBL Partnership Institute for Genome Editing Technologies, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Cofsky JC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Sontheimer EJ; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Wiedenheft B; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA., Fineran PC; Department of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.; Genetics Otago, University of Otago, Dunedin 9016, New Zealand.; Bioprotection Aotearoa, University of Otago, Dunedin 9016, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Otago, Dunedin 9016, New Zealand., Brouns SJJ; Department of Bionanoscience, Delft University of Technology, 2629 HZ Delft, Netherlands.; Kavli Institute of Nanoscience, 2629 HZ Delft, The Netherlands., Sashital DG; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Thomas BC; Metagenomi, Inc., Emeryville, CA 94608, USA., Brown CT; Metagenomi, Inc., Emeryville, CA 94608, USA., Goltsman DSA; Metagenomi, Inc., Emeryville, CA 94608, USA., Barrangou R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27606, USA., Siksnys V; Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Banfield JF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA.; Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA 94720, USA.; EGSB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; The University of Melbourne, Parkville, VIC 3052, Australia., Savage DF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Doudna JA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.; MBIB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Gladstone Institutes, University of California, San Francisco, CA 94158, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D590-D596.