Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Adlard PA"'
© 2019 The Royal Society of Chemistry. We present a novel on-line isotope dilution analysis (IDA) approach for the quantification of isotopically enriched metal labels used in immunohistochemical assisted imaging mass spectrometry. This technique ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::9351a6e3daa46a9782cfc6fb13be8ed8
https://hdl.handle.net/10453/134218
https://hdl.handle.net/10453/134218
Autor:
Billings, JL, Gordon, SL, Rawling, T, Doble, PA, Bush, AI, Adlard, PA, Finkelstein, DI, Hare, DJ
© 2019 International Society for Neurochemistry Treatment with the dopamine (DA) precursor l-3,4-dihydroxyphenylalanine (l-DOPA) provides symptomatic relief arising from DA denervation in Parkinson's disease. Mounting evidence that DA autooxidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e4751d9bdad1eb5a197b1f582fd69112
https://hdl.handle.net/10453/135825
https://hdl.handle.net/10453/135825
© 2017 The Royal Society of Chemistry. The biological transition metals iron (Fe), copper (Cu) and zinc (Zn) are thought to contribute to the neuronal pathologies that occur following traumatic brain injury (TBI), and indeed our previously published
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::80a7d7a97e0f9d6d67e2abf0549d65d1
https://hdl.handle.net/10453/111982
https://hdl.handle.net/10453/111982
Autor:
James, SA, Churches, QI, De Jonge, MD, Birchall, IE, Streltsov, V, McColl, G, Adlard, PA, Hare, DJ
© 2016 American Chemical Society. The metal ions of iron, copper, and zinc have long been associated with the aggregation of β-amyloid (Aβ) plaques in Alzheimer’s disease; an interaction that has been suggested to promote increased oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::19b29a7edb25352806fd99d2364143b5
https://hdl.handle.net/10453/115238
https://hdl.handle.net/10453/115238
Autor:
Portbury, SD, Hare, DJ, Sgambelloni, C, Perronnes, K, Portbury, AJ, Finkelstein, DI, Adlard, PA
This study assessed the therapeutic utility of the autophagy enhancing stable disaccharide trehalose in the Tg2576 transgenic mouse model of Alzheimer's disease (AD) via an oral gavage of a 2% trehalose solution for 31 days. Furthermore, as AD is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::4c5c6277330eff444ba7ba7ee4a393a5
https://hdl.handle.net/10453/159718
https://hdl.handle.net/10453/159718
© 2016 The Royal Society of Chemistry. Traumatic brain injury (TBI) is complicated by a sudden and dramatic change in brain metal levels, including iron (Fe), copper (Cu) and zinc (Zn). Specific 'metallo-pathological' features of TBI include increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b736414caae78615ebab71c30564cdfc
https://hdl.handle.net/10453/41097
https://hdl.handle.net/10453/41097
Autor:
Paul, B, Hare, DJ, Bishop, DP, Paton, C, Nguyen, VT, Cole, N, Niedwiecki, MM, Andreozzi, E, Vais, A, Billings, JL, Bray, L, Bush, AI, McColl, G, Roberts, BR, Adlard, PA, Finkelstein, DI, Hellstrom, J, Hergt, JM, Woodhead, JD, Doble, PA
© The Royal Society of Chemistry 2016. A funder was omitted in the Acknowledgements section and the following text should have been added: This work was also supported by the Ramaciotti Foundation. The Royal Society of Chemistry apologises for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::f63d4ed2ef7194e6ba4335f2cb9705e7
https://hdl.handle.net/10453/132283
https://hdl.handle.net/10453/132283
Autor:
Paul, B, Hare, DJ, Bishop, DP, Paton, C, Nguyen, VT, Cole, N, Niedzwiecki, MM, Andreozzi, E, Vais, A, Billings, JL, Bray, L, Bush, AI, McColl, G, Roberts, BR, Adlard, PA, Finkelstein, DI, Hellstrom, J, Hergt, JM, Woodhead, JD, Doble, PA
© The Royal Society of Chemistry. Correction for 'Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging' by Bence Paul et al., Chem. Sci., 2015, DOI: 10.1039/c5sc0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::2b344c8cff7c8625992377244a680800
https://hdl.handle.net/10453/41100
https://hdl.handle.net/10453/41100
Autor:
Ayton, S, Lei, P, Hare, DJ, Duce, JA, George, JL, Adlard, PA, McLean, C, Rogers, JT, Cherny, RA, Finkelstein, DI, Bush, AI
© 2015 the authors. Elevation of both neuronal iron and nitric oxide (NO) in the substantia nigra are associated with Parkinson’s disease (PD) pathogenesis. We reported previously that the Alzheimer-associated β-amyloid precursor protein (APP) fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6c6a997a2b72cc7fda4dada7a12babae
https://hdl.handle.net/10453/35237
https://hdl.handle.net/10453/35237
Autor:
Ryan, TM, Roberts, BR, McColl, G, Hare, DJ, Doble, PA, Li, QX, Lind, M, Roberts, AM, Mertens, HDT, Kirb, N, Pham, CLL, Hinds, MG, Adlard, PA, Barnham, KJ, Curtain, CC, Masters, CL
©2015 the authors. The extracellular accumulation of amyloid β (A/β) peptides is characteristic of Alzheimer's disease (AD). However, formation of diffusible, oligomeric forms of Aβ, both on and off pathways to amyloid fibrils, is thought to incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::8d02268cdba72635f8e70d3c3978bbe7
https://hdl.handle.net/10453/3523410453/35236
https://hdl.handle.net/10453/3523410453/35236