Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adla Mallareddy"'
Autor:
Paidakula Suresh, Adla Mallareddy, Sowjanya Ghosh, Chandan Kishor, N. Sankara Rao, Manika Pal-Bhadra, M. Janaki Ramaiah, Ahmed Kamal, Anthony Addlagatta, J.N.S.R.C. Murty, S.N.C.V.L. Pushpavalli
Publikováno v:
European Journal of Medicinal Chemistry. 56:166-178
A series of combretastatin-amidobenzothiazole conjugates have been synthesized and evaluated for their anticancer activity. All these compounds exhibited significant anticancer activity and the most potent compound (11a) showed GI(50) values ranging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa14759d4c3ea547063e49354321fe87
https://doi.org/10.1016/j.ejmech.2012.08.021
https://doi.org/10.1016/j.ejmech.2012.08.021
Autor:
M. Janaki Ramaiah, Ch. Ratna Reddy, Manika Pal-Bhadra, Adla Mallareddy, T. Lakshminarayan Reddy, Ahmed Kamal, Nagula Shankaraiah, S. N. C. V. L. Pushpavalli, S. Prabhakar, P. Venkat Reddy
Publikováno v:
European Journal of Medicinal Chemistry. 46:3820-3831
Aiming to develop multitarget drugs for the anticancer treatment, a new class of chalcone-pyrrolo[2,1-c] [1,4]benzodiazepine (PBD) conjugates linked through a 1,2,3-triazole moiety containing alkane spacers has been designed and synthesized. Combinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5558a5e6181792ebc2a0c82482e6f1
https://doi.org/10.1016/j.ejmech.2011.05.050
https://doi.org/10.1016/j.ejmech.2011.05.050
Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents
Autor:
Adla Mallareddy, Pranjal Sarma, Banala Ashwini Kumar, Ahmed Kamal, P. Raju, A. Lavanya, Manika Pal-Bhadra, S.N.C.V.L. Pushpavalli, J. Vinay Gopal, M. Janaki Ramaiah, Paidakula Suresh
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4589-4600
A series of new 4β-acrylamidopodophyllotoxin derivatives ( 13a – o ) were synthesized by coupling of substituted acrylic acids ( 10a – l and 11m – o ) to the 4β-aminopodophyllotoxin. The synthesized derivatives 13a – o were evaluated for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6490da889585953394dc3d83d09cd3b
https://doi.org/10.1016/j.bmc.2011.06.017
https://doi.org/10.1016/j.bmc.2011.06.017
Autor:
Paidakula Suresh, Adla Mallareddy, Nishant Jain, Papagari Venkat Reddy, Thokhir Basha Shaik, Jaki R. Tamboli, Ahmed Kamal, Banala Ashwini Kumar, Shasi V. Kalivendi, P. Raju
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2349-2358
A series of novel conjugates of 4-aza-2,3-didehydropodophyllotoxins ( 11a – w ) were synthesized by a straightforward one-step multicomponent synthesis that demonstrated cytotoxicity against five human cancer cell lines (breast, oral, colon, lung a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941efcf12b9297e4925f52c5519a30dc
https://doi.org/10.1016/j.bmc.2011.02.020
https://doi.org/10.1016/j.bmc.2011.02.020
Publikováno v:
Apoptosis : an international journal on programmed cell death. 20(11)
Apoptosis is essential for normal development and the maintenance of homeostasis. It plays a necessary role to protect against carcinogenesis by eliminating damaged cells. Many studies have demonstrated that the dysregulation of apoptosis results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a3974615171b9506e48851ed3567cc
https://pubmed.ncbi.nlm.nih.gov/26386574
https://pubmed.ncbi.nlm.nih.gov/26386574
Publikováno v:
Novel Apoptotic Regulators in Carcinogenesis ISBN: 9789400749160
A discussion on apoptosis and a variety of heterocyclic compounds that induce apoptosis is presented. A number of heterocyclic compounds containing nitrogen, oxygen or both exhibit significant anticancer properties. Brief discussions on the mode of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7cdf7ef531cabb0b0b9abb211adb91b
https://doi.org/10.1007/978-94-007-4917-7_3
https://doi.org/10.1007/978-94-007-4917-7_3
Autor:
S. N. C. V. L. Pushpavalli, P. Venkat Reddy, M. Janaki Ramaiah, Adla Mallareddy, Nagula Shankaraiah, Ch. Ratna Reddy, Ahmed Kamal, Manika Pal-Bhadra, T. Lakshminarayan Reddy, S. Prabhakar
Publikováno v:
ChemInform. 43
New chalcone-pyrrolobenzodiazepine conjugate (Ia) exhibits promising anticancer activities against selected human cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d330e12725ee68596a2fe7fa683ce0db
https://doi.org/10.1002/chin.201203158
https://doi.org/10.1002/chin.201203158
Autor:
Manika Pal-Bhadra, M. Janaki Ramaiah, Paidakula Suresh, Adla Mallareddy, A. Lavanya, S.N.C.V.L. Pushpavalli, Syed Imthiajali, Ahmed Kamal
Publikováno v:
Bioorganicmedicinal chemistry. 20(6)
A series of new 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide] conjugates of podophyllotoxin ( 11a – j and 15a – g ) were synthesized and evaluated for anticancer activity against six human cancer cell lines and found to be more potent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e6ca430c42467385125836a4fee555
https://pubmed.ncbi.nlm.nih.gov/22364746
https://pubmed.ncbi.nlm.nih.gov/22364746
Carbazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates: design, synthesis, and biological evaluation
Autor:
Pranjal Sarma, M. Janaki Ramaiah, Adla Mallareddy, Aarti Juvekar, S.N.C.V.L. Pushpavalli, Ahmed Kamal, M. P. Narasimha Rao, Rajesh V.C.R.N.C. Shetti, Mukesh Chourasia, K. Srinivasa Reddy, Surekha M. Zingde, P. Swapna, G. Narahari Sastry, Manika Pal-Bhadra
Publikováno v:
MedChemComm. 2:780
A series of carbazole–pyrrolobenzodiazepine conjugates (4a–g and 5a–f) have been designed, and synthesized as anticancer agents. These compounds are prepared by linking the C8-position of DC-81 with a carbazole moiety through simple alkane spac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca74d15238d3af984a21b793abb0be4a
https://doi.org/10.1039/c1md00072a
https://doi.org/10.1039/c1md00072a