Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aditya Y. Sarode"'
Autor:
Soumya Kanti Ghosh, Shubhranshu Zutshi, Aditya Y. Sarode, Mukesh Kumar Jha, Bhaskar Saha, Raki Sudan, Late Parag Sadhale, Sunil Kumar, Somenath Roy
Publikováno v:
Immunology
Leishmania is a protozoan parasite that resides in mammalian macrophages and inflicts the disease known as leishmaniasis. Although prevalent in 88 countries, an anti‐leishmanial vaccine remains elusive. While comparing the virulent and avirulent L.
Autor:
Mukesh Kumar Jha, Surya Prakash Pandey, Neelam Bodhale, Bhaskar Saha, Abdur Rub, Arup Sarkar, Ricardo Silvestre, Aditya Y. Sarode, Debasri Mukherjee, Neetu Srivastava
Publikováno v:
The Journal of Immunology. 204:2734-2753
Leishmania major causes cutaneous leishmaniasis. An antileishmanial vaccine for humans is unavailable. In this study, we report development of two attenuated L. major strains—5ASKH-HP and LV39-HP—by continuous culture (high passage) of the corres
Autor:
Chandan Raybarman, Bhaskar Saha, Trishna Mahanty, Surajit Basak, Ashok Patidar, Aditya Y. Sarode, Surajit Bhattacharjee
Publikováno v:
Scandinavian Journal of Immunology. 92
Toll-like receptors (TLRs), TLR2 in particular, are shown to recognize various glycans and glycolipid ligands resulting in various immune effector functions. As barley β-glucan and zymosan are the glycans implicated in immunomodulation, we examined
Autor:
Bhaskar Saha, Hima Mahor, Aditya Y. Sarode, Mukesh Kumar Jha, Soumya Kanti Ghosh, Uddipan Sarma, Shubhranshu Zutshi
Publikováno v:
iScience
iScience, Vol 23, Iss 9, Pp 101441-(2020)
iScience, Vol 23, Iss 9, Pp 101441-(2020)
Summary CD40-Ligand (CD40L)-CD40 interaction regulates immune responses against pathogens, autoantigens, and tumor and transplantation antigens. Single amino acid mutations within the 115–155 amino acids stretch, which is responsible for CD40L func
Autor:
Ashok Patidar, Bhaskar Saha, Sathishkumar Selvaraj, Aditya Y. Sarode, Prashant Chauhan, Debprasad Chattopadhyay
Publikováno v:
Cytokine. 104:114-123
Random mutations leading to loss of cell cycle control is not a rare occurrence in an organism but the mutated cells are recognized and eliminated preventing the development of a tumor. These potentially tumorigenic cells release damage-associated mo
Publikováno v:
Parasite Immunology. 42
Leishmania major causes mild-to-severe cutaneous lesions resulting in significant disfigurations, if untreated. The drugs are toxic, and drug-resistance parasites are emerging. Therefore, a prophylactic vaccination is an urgent need. As no vaccine is
Autor:
Hima Mahour, Aditya Y. Sarode, Bhaskar Saha, Uddipan Sarma, Soumyakanti Ghosh, Shubhranshu Zutshi, Mukesh Kumar Jha
Publikováno v:
SSRN Electronic Journal.
CD40-Ligand (CD40L)-CD40 interaction regulates immune responses againstpathogens, autoantigens, tumor and transplantation antigens. Single amino acidmutations within the 115-155 amino acids stretch, which is responsible for CD40L functions, result in
Autor:
Mukesh Kumar, Jha, Aditya Y, Sarode, Neelam, Bodhale, Debasri, Mukherjee, Surya Prakash, Pandey, Neetu, Srivastava, Abdur, Rub, Ricardo, Silvestre, Arup, Sarkar, Bhaskar, Saha
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 204(10)
Publikováno v:
Parasite Immunology. 42
Dominant-negative mutation of LdeK1 gene, an eIF2α kinase from Leishmania donovani, revealed its role in translation regulation in response to nutrient starvation earlier. However, whether the kinase influences the infectivity of the parasites which
Publikováno v:
Cytokine. 126:154914
H-/K-Ras and N-Ras isoforms were proposed to lack functional specificities due to similarity in 1–165 amino acids. As recent studies implied Ras isoform-specific developmental effects, we examined their functional specificity using Leishmania major