Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aditya Upadhyaya"'
Autor:
Uddipan Kar, Sara Khaleeq, Priyanka Garg, Madhuraj Bhat, Poorvi Reddy, Venkada Subramanian Vignesh, Aditya Upadhyaya, Mili Das, Ghadiyaram Chakshusmathi, Suman Pandey, Somnath Dutta, Raghavan Varadarajan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Current influenza vaccines need to be updated annually due to mutations in the globular head of the viral surface protein, hemagglutinin (HA). To address this, vaccine candidates have been designed based on the relatively conserved HA stem domain and
Externí odkaz:
https://doaj.org/article/730f11c117784f5ebd34224a7d57e311
Autor:
Shahbaz Ahmed, Mohammad Suhail Khan, Savitha Gayathri, Randhir Singh, Sahil Kumar, Unnatiben Rajeshbhai Patel, Sameer Kumar Malladi, Raju S. Rajmani, Petrus Jansen van Vuren, Shane Riddell, Sarah Goldie, Nidhi Girish, Poorvi Reddy, Aditya Upadhyaya, Suman Pandey, Samreen Siddiqui, Akansha Tyagi, Sujeet Jha, Rajesh Pandey, Oyahida Khatun, Rohan Narayan, Shashank Tripathi, Alexander J. McAuley, Nagendrakumar Balasubramanian Singanallur, Seshadri S. Vasan, Rajesh P. Ringe, Raghavan Varadarajan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Saturation suppressor mutagenesis was used to generate thermostable mutants of the SARS-CoV-2 spike receptor-binding domain (RBD). A triple mutant with an increase in thermal melting temperature of ~7°C with respect to the wild-type B.1 RBD and was
Externí odkaz:
https://doaj.org/article/f5b173c45f564f3cb20fc74fc1645467
Autor:
Shashank Tripathi, Somnath Dutta, Nagendrakumar Balasubramanian Singanallur, Ishika Pramanick, Sujeet Jha, Aditya Upadhyaya, Unnatiben Rajeshbhai Patel, Sankar Bhattacharyya, Parismita Kalita, Rajesh P. Ringe, Akansha Tyagi, Nidhi Girish, Shane Riddell, Sara Khaleeq, Debajyoti Chakraborty, Poorvi Reddy, Mohammad Suhail Khan, Raghavan Varadarajan, Samreen Siddiqui, Nupur Agarwal, Sameer Kumar Malladi, Kawkab Kanjo, Madhuraj Bhat, Shailendra Mani, Sarah Goldie, Savitha Gayathri, Suman Pandey, R. S. Rajmani, Sahil Kumar, Rajesh Pandey, Randhir Singh, Petrus Jansen van Vuren, Alexander J. McAuley, Seshadri S. Vasan
Publikováno v:
ACS infectious diseases. 7(8)
The Receptor Binding Domain (RBD) of SARS-CoV-2 is the primary target of neutralizing antibodies. We designed a trimeric, highly thermotolerant glycan engineered RBD by fusion to a heterologous, poorly immunogenic disulfide linked trimerization domai
Autor:
Uddipan Kar, Sara Khaleeq, Priyanka Garg, Madhuraj Bhat, Poorvi Reddy, Venkada Subramanian Vignesh, Aditya Upadhyaya, Mili Das, Ghadiyaram Chakshusmathi, Suman Pandey, Somnath Dutta, Raghavan Varadarajan
Current influenza vaccines need to be updated annually due to mutations in the globular head of the viral surface protein, hemagglutinin (HA). To address this, vaccine candidates have been designed based on the relatively conserved HA stem domain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376b4de67f2fb243b6101c3bdd44d7a4
https://doi.org/10.1101/2021.03.14.435294
https://doi.org/10.1101/2021.03.14.435294
Autor:
Aditya Upadhyaya, Ishika Pramanick, Mohammad Suhail Khan, Sameer Kumar Malladi, Parismita Kalita, Gautham Nadig, Kawkab Kanjo, Suvankar Dutta, Karthika Thankamani, Raghavan Varadarajan, Savitha Gayathri, Nidhi Girish, Shailendra Mani, Reman K. Singh, Syed Moiz Ahmed, Sankar Bhattacharyya, Jeswin Joseph, M. K. Bhasin, Raj Vs, Suman Pandey, Poorvi Reddy
Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Several use viral vectors or mRNA. In contrast to protein s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47992898efed5573b75e0928184026e8
https://doi.org/10.1101/2020.08.15.252437
https://doi.org/10.1101/2020.08.15.252437
Autor:
Shahbaz Ahmed, Kawkab Kanjo, Somnath Dutta, Ishika Pramanick, Nidhi Girish, Parismita Kalita, Aditya Upadhyaya, Sankar Bhattacharyya, Poorvi Reddy, Karthika Thankamani, M. K. Bhasin, Mohammad Suhail Khan, Randhir Singh, Savitha Gayathri, V. Stalin Raj, Sameer Kumar Malladi, Suman Pandey, Shailendra Mani, Jeswin Joseph, Raghavan Varadarajan, Gautham Nadig, Ramandeep Singh
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Furthermore, several of them use viral vectors or mRNA. In