Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Aditya Rayasam"'
Autor:
Chengyin Yuan, Aditya Rayasam, Alison Moe, Michael Hayward, Clive Wells, Aniko Szabo, Andrew Mackenzie, Nita Salzman, William R. Drobyski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Paneth cell metaplasia (PCM) typically arises in pre-existing gastrointestinal (GI) diseases; however, the mechanistic pathway that induces metaplasia and whether PCM is initiated exclusively by disorders intrinsic to the GI tract is not wel
Externí odkaz:
https://doaj.org/article/bce0bc2d8579490987842242e03115c6
Autor:
Aditya Rayasam, Julie A. Kijak, Lee Kissel, Yun Hwa Choi, Taehee Kim, Martin Hsu, Dinesh Joshi, Collin J. Laaker, Peter Cismaru, Anders Lindstedt, Krisztian Kovacs, Raghu Vemuganti, Shing Yan Chiu, Thanthrige Thiunuwan Priyathilaka, Matyas Sandor, Zsuzsanna Fabry
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved
Externí odkaz:
https://doaj.org/article/e710bc3210a84704b042530e01331994
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106340- (2023)
Summary: Arterial ischemic stroke is common in neonates—1 per 2,300–5,000 births—and therapeutic targets remain insufficiently defined. Sphingosine-1-phosphate receptor 2 (S1PR2), a major regulator of the CNS and immune systems, is injurious in
Externí odkaz:
https://doaj.org/article/ad06a2a15e5649198883a6b9f7def335
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Ischemic stroke induces the activation and recruitment of peripheral leukocytes to the injured brain. These cells can infiltrate the brain through multiple routes, either by penetrating blood–brain barrier or via blood–CSF bar
Externí odkaz:
https://doaj.org/article/3fcf7e253167454c9a44212fd978b08f
Autor:
Aditya Rayasam, William R. Drobyski
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Graft versus host disease (GVHD) is the major non-relapse complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). Unfortunately, GVHD occurs in roughly half of patients following this therapy and can induce severe life
Externí odkaz:
https://doaj.org/article/a102fdc62b844ae9b9c5a472aef56059
Autor:
Martin Hsu, Aditya Rayasam, Julie A. Kijak, Yun Hwa Choi, Jeffrey S. Harding, Sarah A. Marcus, William J. Karpus, Matyas Sandor, Zsuzsanna Fabry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis
Externí odkaz:
https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
Autor:
Jeffrey S. Harding, Melinda Herbath, Yuli Chen, Aditya Rayasam, Anna Ritter, Balazs Csoka, George Hasko, Iacovos P. Michael, Zsuzsanna Fabry, Andras Nagy, Matyas Sandor
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2119-2131.e6 (2019)
Summary: Many autoimmune and infectious diseases are characterized by the formation of granulomas which are inflammatory lesions that consist of spatially organized immune cells. These sites protect the host and control pathogens like Mycobacterium t
Externí odkaz:
https://doaj.org/article/75dad91266a944949ac1dbf4f25645ec
Publikováno v:
Translational Stroke Research.
Injuries in the developing brain cause significant long-term neurological deficits. Emerging clinical and preclinical data have demonstrated that the pathophysiology of neonatal and childhood stroke share similar mechanisms that regulate brain damage
Autor:
Cheng-Yin Yuan, Aditya Rayasam, Alison Moe, Wenwen Xu, Aniko Szabo, Michael Hayward, Clive Wells, Nita Salzman, William R. Drobyski
Paneth cell metaplasia (PCM) typically arises in the setting of pre-existing gastrointestinal (GI) diseases; however, the mechanistic pathway that induces metaplasia and whether PCM is initiated exclusively by disorders intrinsic to the GI tract has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6225e5223818fe05b85226d9c44a6ae1
https://doi.org/10.1101/2022.11.02.514603
https://doi.org/10.1101/2022.11.02.514603
Autor:
Joel Faustino, C. Joakim Ek, Tetyana Chumak, Mary Hamer, Jenny Szu, Andre Obenaus, Zinaida S. Vexler, Carina Mallard, Aditya Rayasam, Amandine Jullienne
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 41, iss 12
J Cereb Blood Flow Metab
J Cereb Blood Flow Metab
Stroke is among the top ten causes of death in children but has received disproportionally little attention. Cerebral arteriopathies account for up to 80% of childhood arterial ischemic stroke (CAIS) cases and are strongly predictive of CAIS recurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c0c32381c91e2eb1caf3ade382cfb8
https://escholarship.org/uc/item/7x25x7z8
https://escholarship.org/uc/item/7x25x7z8