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Akademický článek

Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice

Autor: Ke Yun Chen, Alejandra De Angulo, Xin Guo, Aditya More, Scott A. Ochsner, Eduardo Lopez, David Saul, Weijun Pang, Yuxiang Sun, Neil J. McKenna, Qiang Tong

Publikováno v: Frontiers in Aging, Vol 2 (2022)

Objective: Although PU.1/Spi1 is known as a master regulator for macrophage development and function, we have reported previously that it is also expressed in adipocytes and is transcriptionally induced in obesity. Here, we investigated the role of a

Externí odkaz: https://doaj.org/article/c980109b2e3242598cea0ee28758123b

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Goblet cell tumors of the appendix: Clinical and molecular features

Autor: Abdelrahman M.G. Yousef, Zahra Alavi Naini, Mohammad A. Zeineddine, Saikat Chowdhury, Julia Dansby, Aditya More, Abhineet Uppal, Kanwal Pratap Singh Raghav, Michael J. Overman, Keith F. Fournier, John Paul Y.C. Shen

Publikováno v: Journal of Clinical Oncology. 41:223-223

223 Background: Goblet Cell tumors (GCTs) of the appendix are a rare, distinct, and under studied malignancy. Since 2019 the preferred World Health Organization (WHO) terminology is Goblet Cell Adenocarcinoma (GCA), but previously many terms have bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5aec69096563ff3260d305a95ef68f43
https://doi.org/10.1200/jco.2023.41.4_suppl.223

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Utility of tumor marker levels in predicting survival of patients with appendiceal adenocarcinoma

Autor: Abdelrahman M.G. Yousef, Aditya More, Mohammad A. Zeineddine, Saikat Chowdhury, Yue Gu, Julia Dansby, Zahra Alavi Naini, Abhineet Uppal, Kanwal Pratap Singh Raghav, Michael J. Overman, Keith F. Fournier, John Paul Y.C. Shen

Publikováno v: Journal of Clinical Oncology. 41:221-221

221 Background: Due to the rarity of appendiceal adenocarcinomas (AA), systematic study of these tumors has been limited. Thus, guidelines for the diagnosis and treatment of AA are often based on other related tumor types such as colorectal cancer. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d6600c0099b8b812d0aeb2debe90fa3
https://doi.org/10.1200/jco.2023.41.4_suppl.221

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Adipocyte-Specific Ablation Of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome In Aging Mice

Autor: Yuxiang Sun, David Saul, Weijun Pang, Qiang Tong, Scott A. Ochsner, Alejandra De Angulo, Eduardo Lopez, Aditya More, Neil J. McKenna, Keyun Chen, Xin Guo

ObjectiveAlthough PU.1/Spi1 is known as a master regulator for macrophage development and function, we have reported previously that it is also expressed in adipocytes and is transcriptionally induced in obesity. Here, we investigated the role of adi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::433e5c47b52d5c97509b8216319776d3
https://doi.org/10.1101/2021.08.29.458103

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Abstract 822: Oncogene addiction to GNAS in GNASR201 mutant tumors

Autor: Aditya More, Valsala Haridas, Ichiaki Ito, Saikat Chowdhury, Yue Gu, Natalie W. Fowlkes, John P. Shen

Publikováno v: Cancer Research. 82:822-822

Background: The GNASR201 mutation is the single most frequent cancer-causing mutation across all heterotrimeric G proteins. This gain of function mutation in GNAS drives oncogenesis in appendiceal, colorectal, and gastric adenocarcinoma, as well as I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd7825d15c23145a8e15909d34fd0f4f
https://doi.org/10.1158/1538-7445.am2022-822

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