Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aditya Arra"'
Autor:
Katrin Vogel, Aditya Arra, Holger Lingel, Dirk Bretschneider, Florian Prätsch, Denny Schanze, Martin Zenker, Silke Balk, Dunja Bruder, Robert Geffers, Thomas Hachenberg, Christoph Arens, Monika C. Brunner-Weinzierl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Microbial infections early in life are challenging for the unexperienced immune system. The SARS-CoV-2 pandemic again has highlighted that neonatal, infant, child, and adult T-helper(Th)-cells respond differently to infections, and requires
Externí odkaz:
https://doaj.org/article/d80b20045d7949eebfdb45342967d917
Autor:
Simon Zenke, Mauricio P. Sica, Florian Steinberg, Julia Braun, Alicia Zink, Alina Gavrilov, Alexander Hilger, Aditya Arra, Monika Brunner-Weinzierl, Roland Elling, Niklas Beyersdorf, Tim Lämmermann, Cristian R. Smulski, Jan C. Rohr
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
A number of costimulatory signals are critical to the activation and regulation of T cells, but how the availability or self-regulation of these occurs was previously unclear. Here the authors show a difference in the fate of ligands trogocytosed by
Externí odkaz:
https://doaj.org/article/36d473209bd24a689eb077a758720e5b
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Blockade of surface co-inhibitory receptor programmed cell death-1 (PD-1; CD279) has been established as an important immunotherapeutic approach to treat malignancies. On a cellular level, PD-1 is demonstrated to be of particular importance in inhibi
Externí odkaz:
https://doaj.org/article/0bd19b48b6bc45e1961ea1f2adf2f1c1
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Atopic diseases in childhood are a major burden worldwide and there is still a lack of knowledge about treatable causes. In industrialized countries such as Germany, almost every second child is sensitized to at least one common allergen. Recent stud
Externí odkaz:
https://doaj.org/article/f96f732c89914cb9ba63aba6b390d640
Autor:
Aditya Arra, Maximilian Pech, Hang Fu, Holger Lingel, Franziska Braun, Christian Beyer, Myra Spiliopoulou, Barbara M. Bröker, Karen Lampe, Christoph Arens, Katrin Vogel, Mandy Pierau, Monika C. Brunner-Weinzierl
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The monoclonal antibody against CTLA-4, Ipilimumab, is a first-in-class immune-checkpoint inhibitor approved for treatment of advanced melanoma in adults but not extensively studied in children. In light of the fact that the immune response early in
Externí odkaz:
https://doaj.org/article/184fafbd6a134358b3cb40addcf9ccf2
Autor:
Aditya Arra, Holger Lingel, Benno Kuropka, Jonas Pick, Tina Schnoeder, Thomas Fischer, Christian Freund, Mandy Pierau, Monika C. Brunner-Weinzierl
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
As the blockade of inhibitory surface-molecules such as CTLA-4 on T cells has led to recent advances in antitumor immune therapy, there is great interest in identifying novel mechanisms of action of CD8+ T cells to evoke effective cytotoxic antitumor
Externí odkaz:
https://doaj.org/article/d44711ac464147418f16f40eff37397b
Autor:
Christiane Majer, Holger Lingel, Aditya Arra, Hans-Gert Heuft, Dirk Bretschneider, Silke Balk, Katrin Vogel, Monika C. Brunner-Weinzierl
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5662
Newborns are highly susceptible to infections; however, the underlying mechanisms that regulate the anti-microbial T-helper cells shortly after birth remain incompletely understood. To address neonatal antigen-specific human T-cell responses against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1de6aedcd41a88b1c5b0fbd678938d
https://doi.org/10.3390/ijms24065662
https://doi.org/10.3390/ijms24065662
Publikováno v:
Materials Today: Proceedings. 44:587-595
Currently, various high lift devices are being employed in the general aviation industry. The performance of these high lift devices depends on various parameters, among which the geometrical or positional parameters are one of the most important as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::219b7abfd84749158d211f02bde0dd69
https://doi.org/10.1016/j.matpr.2020.10.355
https://doi.org/10.1016/j.matpr.2020.10.355
Autor:
Katrin Pansy, Karoline Fechter, Kerstin Wenzl, Aditya Arra, Joseph P. Novak, Marta Szmyra, Sandra Haingartner, Alan G. Ramsay, Anne J. Novak, Hildegard T. Greinix, Christine Beham-Schmid, Peter Neumeister, Alexander J.A. Deutsch
Publikováno v:
Blood. 140:2038-2039
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3db3a40efb1887cb30bd26e41b274202
https://doi.org/10.1182/blood-2022-163034
https://doi.org/10.1182/blood-2022-163034
Autor:
Simon Zenke, Mauricio P. Sica, Florian Steinberg, Julia Braun, Alicia Zink, Alina Gavrilov, Alexander Hilger, Aditya Arra, Monika Brunner-Weinzierl, Roland Elling, Niklas Beyersdorf, Tim Lämmermann, Cristian R. Smulski, Jan C. Rohr
Publikováno v:
Nature Communications
Intercellular communication is crucial for collective regulation of cellular behaviors. While clustering T cells have been shown to mutually control the production of key communication signals, it is unclear whether they also jointly regulate their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b0543764ca6eda93e9171a26dba251
https://pubmed.ncbi.nlm.nih.gov/36309492
https://pubmed.ncbi.nlm.nih.gov/36309492