Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Aditi Sapre"'
Autor:
Thomas Sudhop, Michael Reber, Diane Tribble, Aditi Sapre, William Taggart, Patrice Gibbons, Thomas Musliner, Klaus von Bergmann, Dieter Lütjohann
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 10, Pp 2117-2123 (2009)
This study evaluates changes in cholesterol balance in hypercholesterolemic subjects following treatment with an inhibitor of cholesterol absorption or cholesterol synthesis or coadministration of both agents. This was a randomized, double blind, pla
Externí odkaz:
https://doaj.org/article/245ccf5a96b741e9840048470f179342
Autor:
Heather, Platt, Tosin, Omole, Jose, Cardona, Neil J, Fraser, Richard A, Mularski, Charles, Andrews, Nizar, Daboul, Nancy, Gallagher, Aditi, Sapre, Jianing, Li, Adam, Polis, Doreen, Fernsler, Gretchen, Tamms, Weifeng, Xu, Rocio, Murphy, Julie, Skinner, Joseph, Joyce, Luwy, Musey
Publikováno v:
The Lancet Infectious Diseases. 23:233-246
A pneumococcal conjugate vaccine (PCV) specifically focused on serotypes associated with adult residual disease burden is urgently needed. We aimed to assess V116, an investigational 21-valent PCV, that contains pneumococcal polysaccharides (PnPs), w
Autor:
Heather Platt, Doreen Fernsler, Nancy Gallagher, Aditi Sapre, Adam Polis, Lori Hall, Gretchen Tamms, Howard Schwartz, Julie Skinner, Joseph Joyce, Rocio Murphy, Luwy Musey
Publikováno v:
JAC-Antimicrobial Resistance. 5
Background V116, an investigational 21-valent PCV, contains the following pneumococcal polysaccharides (PnPs): 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 16F, 17F, 19A, 20, 22F, 23A, 23B, 24F, 31, 33F, 35B, and a de-O-acetylated 15B (deOAc15B). This phase
Autor:
Sukrut Shah, Ignacio Rodriguez Briones, Tanya B. Ashraf, Yale B. Mitchel, Yugang Dong, Wayne Huey-Heng Sheu, Sandra C. Tobias, Tayfun Sahin, Amy O. Johnson-Levonas, Yulia Moiseeva, P Rossi, Duk-Hyun Kang, Aditi Sapre, Christie M. Ballantyne, Ping Ye
Publikováno v:
The American journal of cardiology. 120(4)
This phase 3, multiregional, randomized, double-blind, placebo-controlled study assessed the efficacy/safety profile of anacetrapib added to ongoing therapy with statin ± other lipid-modifying therapies in patients with hypercholesterolemia who were
Autor:
Aditi Sapre, Klaus von Bergmann, Dieter Lütjohann, Patrice H. Gibbons, Thomas Musliner, William Taggart, Thomas Sudhop, Michael Reber, Diane Tribble
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 10, Pp 2117-2123 (2009)
This study evaluates changes in cholesterol balance in hypercholesterolemic subjects following treatment with an inhibitor of cholesterol absorption or cholesterol synthesis or coadministration of both agents. This was a randomized, double blind, pla
Autor:
Debra Kush, Da Yi Hu, Christine McCrary Sisk, Waheeda Sirah, Hyo-Soo Kim, Ji Liu, John F. Paolini, Aditi Sapre, Darbie Maccubbin
Publikováno v:
Journal of Clinical Lipidology. 3:179-186
Niacin has proven lipid-modifying efficacy and cardiovascular benefit; however, it is underused because of skin flushing, a process mediated primarily by prostaglandin D(2) (PGD(2)). Laropiprant (LRPT), a PGD(2) receptor (DP1) antagonist that mitigat
Autor:
Geraldine Macdonell, Dieter Lütjohann, Thomas Musliner, Waheeda Sirah, J. Lin, Amish P. Shah, Amy O. Johnson-Levonas, Aditi Sapre, K. von Bergmann
Publikováno v:
International Journal of Clinical Practice. 62:1499-1510
Summary Objective: To assess the long-term efficacy and safety profile of ezetimibe 10 mg/day in patients with homozygous sitosterolemia. Methods: This was an extension of a multi-centre, randomised, double-blind, placebo-controlled base study in whi
Autor:
Gerald Salen, Waheeda Sirah, C. McCrary Sisk, K. von Bergmann, Thomas Musliner, Dieter Lütjohann, Aditi Sapre, D. Cselovszky
Publikováno v:
International Journal of Clinical Practice. 62:995-1000
Summary Objective: To assess the effect of ezetimibe (EZE) 40 mg/day on non-cholesterol sterol plasma concentrations in patients with homozygous sitosterolaemia (HoS). Methods: This was a multi-centre, randomised, double-blind, placebo-controlled par
Publikováno v:
Clinical Therapeutics. 29:2419-2432
Background: Cholesterol-rich lipoproteins, including low-density lipoprotein cholesterol (LDL-C), intermediate-density lipoprotein cholesterol (IDL-C), and very-low-density lipoprotein cholesterol (VLDL-C), are known to promote atherosclerosis. Ezeti
Autor:
Jennifer Fable, Michiel Koeijvoets, G. Kees Hovingh, Yale B. Mitchel, Sukrut Shah, Amy O. Johnson-Levonas, Jean Bergeron, Naab Al-Saady, John J.P. Kastelein, Gisle Langslet, Aditi Sapre, Joost Besseling, John Hunter
Publikováno v:
Lancet, 385(9983), 2153-2161. Elsevier Limited
Present guidelines emphasise the importance of low concentrations of LDL cholesterol (LDL-C) in patients with familial hypercholesterolaemia. In most patients with the disease, however, these concentrations are not achieved with present treatments, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d106347dfa1330a984263e6f41a3ca
https://pure.amc.nl/en/publications/anacetrapib-as-lipidmodifying-therapy-in-patients-with-heterozygous-familial-hypercholesterolaemia-realize-a-randomised-doubleblind-placebocontrolled-phase-3-study(f0a930ee-34e5-4054-aba1-76b6963141e0).html
https://pure.amc.nl/en/publications/anacetrapib-as-lipidmodifying-therapy-in-patients-with-heterozygous-familial-hypercholesterolaemia-realize-a-randomised-doubleblind-placebocontrolled-phase-3-study(f0a930ee-34e5-4054-aba1-76b6963141e0).html