Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aditi Nandi"'
Autor:
Rio S. Boothello, Nehru Viji Sankaranarayanan, Jyothi C. Sistla, Balaji Nagarajan, Chetna Sharon, John E. Chittum, Rabiya Y. Niyaz, Swarnali Roy, Aditi Nandi, Connor P. O'Hara, Rahaman Navaz Gangji, Daniel K. Afosah, Ravikumar Ongolu, Bhaumik B. Patel, Umesh R. Desai
Publikováno v:
Angewandte Chemie (International ed. in English). 61(49)
The insulin-like growth factor-1 receptor (IGF-1R) is a receptor tyrosine kinase (RTK) that plays critical roles in cancer. Microarray, computational, thermodynamic, and cellular imaging studies reveal that activation of IGF-1R by its cognate ligand
Publikováno v:
Cancer Research. 83:1808-1808
Background: Immune-modulating therapies have limited efficacy in colorectal cancers (CRC). This resistance to treatment is attributed to low neoantigen expression, and the inability of T cells to kill HLA-I negative tumor cells, especially cancer ste
Publikováno v:
ACS applied bio materials. 2(1)
Mitochondrion, the powerhouse of the cells, controls bioenergetics, biosynthesis, metabolism, and signaling. Consequently, it has become an unorthodox target for cancer therapeutics. However, specific targeting of mitochondria into subcellular milieu
Autor:
Roshan Keshari, Amarjitsing Rajput, Aditi Nandi, Riyaz Ali M. Osmani, Nadim Ahamad, Rinti Banerjee
Publikováno v:
Biomaterials Science Series ISBN: 9781839164989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb5d7f58323465665355324ded32997
https://doi.org/10.1039/9781839166235-00269
https://doi.org/10.1039/9781839166235-00269
Publikováno v:
Journal of Materials Chemistry B. 7:4191-4197
DNA topoisomerases and nuclear DNA are important targets for cancer therapy. However, DNA topoisomerase inhibitors and DNA damaging drugs demonstrate a large window of side effects in the clinic. Graphene oxide based biocompatible and biodegradable n
Publikováno v:
Nanoscale advances. 1(12)
Cancer chemotherapy had been dominated by the use of small molecule DNA damaging drugs. Eventually, the emergence of DNA damage repair machinery in cancer cells has led to combination therapy with the DNA topology controlling enzyme, topoisomerase I
Publikováno v:
Nanoscale. 11(7)
The endoplasmic reticulum (ER) is one of the most important organelles controlling myriads of cellular functions including protein folding/misfolding/unfolding, calcium ion homeostasis and lipid biosynthesis. Subsequently, due to its functional dysre
Publikováno v:
Chemical communications (Cambridge, England). 53(8)
This report describes the hitherto unobserved cisplatin induced self-assembly of 2D-graphene oxide sheets into 3D-spherical nano-scale particles. These nanoparticles can encompass dual DNA damaging drugs simultaneously. A combination of confocal micr