Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aditi Chaudhari"'
Autor:
Aditi Chaudhari, Katarina Ejeskär, Yvonne Wettergren, C. Ronald Kahn, Victoria Rotter Sopasakis
Publikováno v:
F1000Research, Vol 6 (2018)
Background: Class IA phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) is an integral mediator of insulin signaling. The p110 catalytic and p85 regulatory subunits of PI3K are the products of separate genes, and while they come together to make t
Externí odkaz:
https://doaj.org/article/dd3ace330a724acda1dd5eaf5f7dc0b9
Autor:
Jan Borén, Yvonne Wettergren, Annika Lundqvist, Sashidhar Bandaru, Marcus Ståhlman, Daniel Krumlinde, Kristina Skålén, Aditi Chaudhari, Levent M. Akyürek, Victoria Rotter Sopasakis, Katarina Ejeskär
The phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) catalytic subunit p110α is the most frequently mutated kinase in human cancer, and the hot spot mutations E542K, E545K, and H1047R are the most common mutations in p110α. Very little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9d9c29f97d60fbcb6f5eac2edc78d0
https://europepmc.org/articles/PMC4561724/
https://europepmc.org/articles/PMC4561724/
