Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aditi, Tandale"'
Autor:
J. Niclas Frei, Richard W. Broadhurst, Mark J. Bostock, Andras Solt, Andrew J. Y. Jones, Florian Gabriel, Aditi Tandale, Binesh Shrestha, Daniel Nietlispach
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The β1-adrenergic receptor (β1AR) is a G-protein-coupled receptor (GPCRs) that binds catecholamine ligands. Here the authors employ site-specific labelling and 19F NMR measurements to characterise the structural changes and dynamics in the cytoplas
Externí odkaz:
https://doaj.org/article/ac8049b430b14cfaa49fd36fc3a5beb9
Publikováno v:
Molecules, Vol 25, Iss 20, p 4729 (2020)
Over the past decade, the vast amount of information generated through structural and biophysical studies of GPCRs has provided unprecedented mechanistic insight into the complex signalling behaviour of these receptors. With this recent information s
Externí odkaz:
https://doaj.org/article/6ed8e09b00e94c258fb9f21192245ceb
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1869(4)
The β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8362301cc2a0a0cfe898bd333869f0bf
https://pubmed.ncbi.nlm.nih.gov/33453412
https://pubmed.ncbi.nlm.nih.gov/33453412
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1869:140605
The β2-adrenergic receptor (β2AR) is a member of the G protein-coupled receptor (GPCR) family that is an important drug target for asthma and COPD. Clinical studies coupled with biochemical data have identified a critical receptor variant, Thr164Il
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a491cff23ce0b508fc7d99fa314465b4
https://doi.org/10.1016/j.bbapap.2021.140605
https://doi.org/10.1016/j.bbapap.2021.140605
Publikováno v:
Scientific Reports
The human β2-adrenergic receptor (β2AR) belongs to the G protein-coupled receptor (GPCR) family and due to its central role in bronchodilation, is an important drug target. The inter-individual variability in β2AR has been implicated in disease su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9f47a3f2bb9c028b1361d727a91762
https://doi.org/10.1038/srep24379
https://doi.org/10.1038/srep24379