Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Adith Venkiteshwaran"'
Publikováno v:
Biotechnology and Bioengineering. 112:2115-2122
Virus filtration is used to ensure drug safety in the production of biotherapeutics. Several recent studies have shown a dramatic decrease in virus retention as a result of a process disruption, e.g., a transient pressure release. In this work, a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16c019e35521c5fe519187e053ce2a0e
https://doi.org/10.1002/bit.25614
https://doi.org/10.1002/bit.25614
Autor:
Robert Langer, Georges Belfort, James E. Kilduff, Daniel G. Anderson, Adith Venkiteshwaran, Mingyan Zhou, Hongwei Liu
Publikováno v:
Journal of materials chemistry. 21(3)
A novel high throughput method for synthesis and screening of customized protein-resistant surfaces was developed. This method is an inexpensive, fast, reproducible and scalable approach to synthesize and screen protein-resistant surfaces appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034f2fdd100ce332a33e2ded72d1a350
https://pubmed.ncbi.nlm.nih.gov/28210070
https://pubmed.ncbi.nlm.nih.gov/28210070
Publikováno v:
Biotechnology and Bioengineering. 110:229-239
Virus-removal filtration technology is commonly used in the manufacturing process for biologics to remove potential viral contaminants. Virus-removal filters designed for retaining parvovirus, one of the smallest mammalian viruses, are considered an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4aee2c08b258219a3d6b95ddbf54cee
https://doi.org/10.1002/bit.24600
https://doi.org/10.1002/bit.24600
Autor:
Dayue Chen, Kurt Brorson, Rakhi B. Shah, Erik K. Read, Daniel Strauss, Adith Venkiteshwaran, Scott Lute, A Kreuzman, George Miesegaes, Parviz Ayazi Shamlou
Publikováno v:
Biotechnology and Bioengineering. 109:2048-2058
Traditionally, post-production culture harvest capture of therapeutic monoclonal antibodies (mAbs) is performed using Protein A chromatography. We investigated the efficiency and robustness of cation exchange chromatography (CEX) in an effort to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3b84a5f99618d8d7be0ada3ad19671
https://doi.org/10.1002/bit.24480
https://doi.org/10.1002/bit.24480
Autor:
Adith Venkiteshwaran, Georges Belfort
Publikováno v:
Journal of Membrane Science. 357:105-108
Increased titers from 2 to 10 mg/ml represents a major future challenge for recovery of desirable proteins during downstream processing. Pressure-driven microfiltration using synthetic membranes, due to its advantages such as speed, no phase change,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57469a65019d4572dfcf67a00f564d31
https://doi.org/10.1016/j.memsci.2010.04.007
https://doi.org/10.1016/j.memsci.2010.04.007
Publikováno v:
Biotechnology and Bioengineering. 101:957-966
Efficient and economic recovery of immunoglobulins (Igs) from complex biological fluids such as serum, cell culture supernatant or fermentation cell lysate or supernatant, represents a substantial challenge in biotechnology. Methods such as protein A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373c6917cd30780517c03af2db0b4105
https://doi.org/10.1002/bit.21964
https://doi.org/10.1002/bit.21964
Publikováno v:
Biotechnology Progress. 21:1013-1025
A global model and algorithm that predicts the performance of crossflow MF and UF process individually or in combination in the laminar flow regime is presented and successfully tested. The model accounts for solute polydispersity, ionic environment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54242f7edccb1db0ff072083713b0ab5
https://doi.org/10.1021/bp050184r
https://doi.org/10.1021/bp050184r
Autor:
Jennifer N. Earley, Andrew L. Zydney, Ki-Joo Sung, Matthew R. Micklin, Adith Venkiteshwaran, Shudipto K. Dishari
Publikováno v:
Biotechnology progress. 31(5)
Virus filtration can provide a robust method for removal of adventitious parvoviruses in the production of biotherapeutics. Although virus filtration is typically thought to function by a purely size-based removal mechanism, there is limited data in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df57c300dbf397a2c61abc5623adc5e9
https://pubmed.ncbi.nlm.nih.gov/26081350
https://pubmed.ncbi.nlm.nih.gov/26081350
Publikováno v:
Biotechnology and bioengineering. 112(10)
Virus filtration is used to ensure drug safety in the production of biotherapeutics. Several recent studies have shown a dramatic decrease in virus retention as a result of a process disruption, e.g., a transient pressure release. In this work, a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c9cc8110b0699024e993b1c715c0e9e
https://pubmed.ncbi.nlm.nih.gov/25898823
https://pubmed.ncbi.nlm.nih.gov/25898823
Autor:
Juliana, Stuckey, Daniel, Strauss, Adith, Venkiteshwaran, Jinxin, Gao, Wen, Luo, Michelle, Quertinmont, Sean, O'Donnell, Dayue, Chen
Publikováno v:
Biotechnology progress. 30(1)
Viral filtration is routinely incorporated into the downstream purification processes for the production of biologics produced in mammalian cell cultures (MCC) to remove potential viral contaminants. In recent years, the use of retentive filters desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a224d23622dd33383c18e63d3f48b3c3
https://pubmed.ncbi.nlm.nih.gov/24123923
https://pubmed.ncbi.nlm.nih.gov/24123923