Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adit B. Alreja"'
Autor:
Adit B. Alreja, Amanda E. Appel, Jinyi C. Zhu, Sean P. Riley, Norberto Gonzalez-Juarbe, Daniel C. Nelson
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTStreptococcus pneumoniae (Spn), a Gram-positive bacterium, is responsible for causing a wide variety of invasive infections. The emergence of multi-drug antibiotic resistance has prompted the search for antimicrobial alternatives. Phage-deriv
Externí odkaz:
https://doaj.org/article/2da6a8537ea942b5b5f649741e1a70ef
Autor:
Shelby D. Foor, Kalvis Brangulis, Anil K. Shakya, Vipin S. Rana, Sandhya Bista, Chrysoula Kitsou, Michael Ronzetti, Adit B. Alreja, Sara B. Linden, Amanda S. Altieri, Bolormaa Baljinnyam, Inara Akopjana, Daniel C. Nelson, Anton Simeonov, Osnat Herzberg, Melissa J. Caimano, Utpal Pal
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Borrelia burgdorferi, the pathogen of Lyme disease, encodes many conserved proteins of unknown structure or function, including ones that serve essential roles in microbial infectivity. One such protein is BB0238, which folds into a two-doma
Externí odkaz:
https://doaj.org/article/41e800ac2ac0401a9b693dae646e6521
Autor:
Kinlin L. Chao, Xiaoran Shang, Julia Greenfield, Sara B. Linden, Adit B. Alreja, Daniel C. Nelson, Osnat Herzberg
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Four tailspike proteins (TSP1-4) of Escherichia coli O157:H7 bacteriophage CBA120 enable infection of multiple hosts. They form a branched complex that attaches to the tail baseplate. Each TSP recognizes a different lipopolysaccharide on the
Externí odkaz:
https://doaj.org/article/095f0623a6704655bc2e994ffe5f0eb1
Autor:
Adit B. Alreja, Sara B. Linden, Harrison R. Lee, Kinlin L. Chao, Osnat Herzberg, Daniel C. Nelson
Publikováno v:
ACS Infectious Diseases. 9:1092-1104
Autor:
Yuncheng Wang, Dipesh Khanal, Adit B. Alreja, Hang Yang, Rachel YK Chang, Waiting Tai, Mengyu Li, Daniel C. Nelson, Warwick J Britton, Hak-Kim Chan
Publikováno v:
International Journal of Pharmaceutics. 635:122679
Publikováno v:
Current opinion in biotechnology. 68
The decline in new antibiotic candidates combined with an increase in antibiotic-resistance necessitates development of alternative antimicrobials. Bacteriophage-encoded endolysins (lysins) are a class of peptidoglycan hydrolases that have been propo