Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Adison Wong"'
Autor:
Viknesvaran Selvarajan, Denise Bei Lin Teo, Chaw-Chiea Chang, Yuen Ling Ng, Nge Cheong, Jaichandran Sivalingam, Soo Hean Gary Khoo, Adison Wong, Bernard Liat Wen Loo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cell and gene therapies are an innovative solution to various severe diseases and unfulfilled needs. Adoptive cell therapy (ACT), a form of cellular immunotherapies, has been favored in recent years due to the approval of chimeric antigen receptor CA
Externí odkaz:
https://doaj.org/article/3d9028b801ef462494f238a602103ffe
Autor:
Shuhui Wang, Xu Sun, Yuqing Han, Zhuo Li, Xiaocong Lu, Hongrui Shi, Cui-ying Zhang, Adison Wong, Aiqun Yu
Publikováno v:
Metabolic Engineering Communications, Vol 18, Iss , Pp e00240- (2024)
Squalene is a highly sought-after triterpene compound in growing demand, and its production offers a promising avenue for circular economy practices. In this study, we applied metabolic engineering principles to enhance squalene production in the non
Externí odkaz:
https://doaj.org/article/4b8f18b9cb66473d85c2e189acd38fb9
Autor:
Jing Kong, Lin Miao, Zhihui Lu, Shuhui Wang, Baixiang Zhao, Cuiying Zhang, Dongguang Xiao, Desmond Teo, Susanna Su Jan Leong, Adison Wong, Aiqun Yu
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Background Amyrin is an important triterpenoid and precursor to a wide range of cosmetic, pharmaceutical and nutraceutical products. In this study, we metabolically engineered the oleaginous yeast, Yarrowia lipolytica to produce α- and β-a
Externí odkaz:
https://doaj.org/article/a4830eef275842578111ebd4d260e704
Autor:
Lanxin Rong, Lin Miao, Shuhui Wang, Yaping Wang, Shiqi Liu, Zhihui Lu, Baixiang Zhao, Cuiying Zhang, Dongguang Xiao, Krithi Pushpanathan, Adison Wong, Aiqun Yu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Itaconic acid (IA) is a high-value organic acid with a plethora of industrial applications. In this study, we seek to develop a microbial cell factory that could utilize waste cooking oil (WCO) as raw material for circular and cost-effective producti
Externí odkaz:
https://doaj.org/article/b8f0685681cf46cc8eca592e4128b4bd
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Cells are exposed to shifts in environmental pH, which direct their metabolism and behavior. Here the authors design pH-sensing riboswitches to create a gene expression program, digitalize the system to respond to a narrow pH range and apply it to ev
Externí odkaz:
https://doaj.org/article/5c2c92d882484cfb8b1ed9af3d8bee95
Autor:
In Young Hwang, Elvin Koh, Adison Wong, John C. March, William E. Bentley, Yung Seng Lee, Matthew Wook Chang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Bacteria can be engineered to kill specific pathogens. Here, the authors modify and optimize a synthetic genetic system in a probiotic strain ofEscherichia coli, and show that the engineered probiotic can sense and kill the pathogen Pseudomonas aerug
Externí odkaz:
https://doaj.org/article/a5c160db7f9b4ac99fc5558113c39f95
Autor:
Lanxin, Rong, Lin, Miao, Shuhui, Wang, Yaping, Wang, Shiqi, Liu, Zhihui, Lu, Baixiang, Zhao, Cuiying, Zhang, Dongguang, Xiao, Krithi, Pushpanathan, Adison, Wong, Aiqun, Yu
Publikováno v:
Frontiers in bioengineering and biotechnology. 10
Itaconic acid (IA) is a high-value organic acid with a plethora of industrial applications. In this study, we seek to develop a microbial cell factory that could utilize waste cooking oil (WCO) as raw material for circular and cost-effective producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf54cb33f6a748e86705e205dcd385bb
https://pubmed.ncbi.nlm.nih.gov/35547171
https://pubmed.ncbi.nlm.nih.gov/35547171
Autor:
Shenglong Li, Lanxin Rong, Shuhui Wang, Shiqi Liu, Zhihui Lu, Lin Miao, Baixiang Zhao, Cuiying Zhang, Dongguang Xiao, Krithi Pushpanathan, Adison Wong, Aiqun Yu
Publikováno v:
Chemical Engineering Science. 249:117342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35f6b56757561dd7ffd42c57a6cdbc8
https://doi.org/10.1016/j.ces.2021.117342
https://doi.org/10.1016/j.ces.2021.117342
Autor:
Adison Wong, Maurice Ht Ling
Publikováno v:
Encyclopedia of Bioinformatics and Computational Biology (3)
Transcription is the first stage of gene expression, leading to the eventual determination of protein abundance and affecting metabolism. Hence, there is a need to measure and characterize transcriptional activities accurately. This article discusses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a80ae0d2cce1e374577ab746f30d6407
https://doi.org/10.1016/b978-0-12-809633-8.20446-9
https://doi.org/10.1016/b978-0-12-809633-8.20446-9
Publikováno v:
Biotechnology and Bioengineering. 113:842-851
Fatty aldehydes and alcohols are valuable precursors used in the industrial manufacturing of a myriad of specialty products. Herein, we demonstrate the de novo production of odd chain-length fatty aldehydes and fatty alcohols in Saccharomyces cerevis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62d2e4e206b07c48530dee33db11560
https://doi.org/10.1002/bit.25856
https://doi.org/10.1002/bit.25856